Results 201 to 210 of about 472,431 (277)

Management of Bartholin's Gland Carcinoma in a Perimenopausal Woman: A Case Report. [PDF]

open access: yesAm J Case Rep
Borawski P   +7 more
europepmc   +1 more source

Nano Delivery Strategy Opens Effective Avenues for the Treatment of Colorectal Cancer

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT Colorectal cancer (CRC) presents significant therapeutic challenges because of chemoresistance, systemic toxicity, and the complexity of the tumor microenvironment (TME). Nanodrug delivery systems (NDDS) have emerged as versatile platforms capable of overcoming these limitations by enhancing tumor accumulation, improving pharmacokinetics, and ...
Qiurong Wei   +7 more
wiley   +1 more source

Single‐Cell Transcriptomic Analysis Reveals Epithelial‐Mesenchymal Transition and Key Gene AGRN as a Universal Programme in Gastrointestinal Tumours by an Artificial Intelligence‐Derived Prognostic Index

open access: yesMed Research, EarlyView.
Intra‐tumour heterogeneity is present in gastrointestinal tumours at the single‐cell level. Cell cycling, EMT, MYC and TNF‐α are the four main consensus meta‐programs in gastrointestinal tumours. Then, a prognostic model based on intratumoral heterogeneity was constructed using an artificial intelligence‐derived prognostic index.
Zhizhan Ni   +12 more
wiley   +1 more source

Altered Dopamine Metabolism and Response to Treatment with Levodopa/Carbidopa in MCT8 Deficiency

open access: yesMovement Disorders, EarlyView.
Abstract Background Allan‐Herndon‐Dudley syndrome (AHDS)/monocarboxylate transporter 8 (MCT8) deficiency is a rare X‐linked encephalopathy caused by SLC16A2 variants, impairing thyroid hormone (TH) transport into the brain. This leads to early central nervous system (CNS) TH deficiency, affecting brain maturation.
Fabio Bruschi   +12 more
wiley   +1 more source

Motion‐ and Field‐Robust Mesoscopic Whole‐Brain T2*$$ {T}_2^{\ast } $$‐Weighted Imaging at 7 and 11.7 T Using Servo Navigation

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To mitigate artifacts related to motion and field changes in high‐resolution T2*$$ {T}_2^{\ast } $$‐weighted human brain imaging using servo navigation at ultra‐high fields up to 11.7 T. Methods MR‐based servo navigators were integrated into a segmented 3D‐EPI sequence to allow for prospective correction of involuntary head motion and ...
Matthias Serger   +15 more
wiley   +1 more source

A phase 2 study of GI-6207 in patients with recurrent medullary thyroid cancer. [PDF]

open access: yesOncologist
Del Rivero J   +9 more
europepmc   +1 more source

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