In vitro screening of nutrients regulating sheep intramuscular angiogenesis, adipogenesis, and lipid deposition using an organoid model. [PDF]
Li Y +14 more
europepmc +1 more source
Enhancing gene therapy vectors manufacturing: CEBPA as a master regulator of rAAV biogenesis. [PDF]
Moura F +6 more
europepmc +1 more source
Identification of transcription factors that regulate placental sFLT1 expression. [PDF]
Yong Q +7 more
europepmc +1 more source
Transient SUMOylation inhibition in human pre-adipocytes stably imprints a transcriptional beiging fate. [PDF]
Nothnagel PMC +10 more
europepmc +1 more source
Activity of the SWI/SNF complex is indispensable for syncytiotrophoblast formation. [PDF]
Papuchova H +6 more
europepmc +1 more source
Construction of an immune-related prognostic model and functional analysis of CEBPB in uveal melanoma: A STROBE-compliant observational study. [PDF]
Tao Y +5 more
europepmc +1 more source
C/EBPβ-mediated PARP1 Suppression Drives Tumor Progression of Aneuploid Cells
Cheng P +14 more
europepmc +1 more source
Cell-Penetrating CEBPB and CEBPD Leucine Zipper Decoys as Broadly Acting Anti-Cancer Agents [PDF]
Transcription factors are key players underlying cancer formation, growth, survival, metastasis and treatment resistance, yet few drugs exist to directly target them. Here, we characterized the in vitro and in vivo anti-cancer efficacy of novel synthetic cell-penetrating peptides (Bpep and Dpep) designed to interfere with the formation of active ...
Lloyd A Greene +2 more
exaly +5 more sources
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Regulatory evolution through divergence of a phosphoswitch in the transcription factor CEBPB
Nature, 2011There is an emerging consensus that gene regulation evolves through changes in cis-regulatory elements and transcription factors. Although it is clear how nucleotide substitutions in cis-regulatory elements affect gene expression, it is not clear how amino-acid substitutions in transcription factors influence gene regulation.
Gunter P Wagner
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Metformin inhibits human non-small cell lung cancer by regulating AMPK–CEBPB–PDL1 signaling pathway
Cancer Immunology, Immunotherapy, 2021Metformin has been found to have inhibitory effects on a variety of tumors. However, its effects on non-small cell lung cancer (NSCLC) remain unclear. We demonstrated that metformin could inhibit the proliferation of A549 and H1299 cells. RNA transcriptome sequencing revealed that PDL1 was significantly downregulated in both cell types following ...
Tao Lu, Ming Li, Guoshu Bi
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