Results 171 to 180 of about 13,695 (188)
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The transcription factors Creb1 and CEBPB regulate Sox9 promoter activity in TM4 Sertoli cells
Gene, 2023In Sertoli cells, the Sox9 gene is essential for testicular development and normal spermatogenesis. SOX9 is critical for postnatal Sertoli cells differentiation and proliferation in the testis. However, the molecular mechanisms that specifically regulate its expression are not entirely understood.
Mariama Diawara +3 more
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A novel PAK4-CEBPB-CLDN4 axis involving in breast cancer cell migration and invasion
Biochemical and Biophysical Research Communications, 2019Claudin-4 (CLDN4), a crucial member of tight junction proteins, is aberrantly expressed in breast cancer cells and contributes to cell migration and invasion. However, the mechanisms controlling CLDN4 expression in breast cancer are poorly understood.
Nanxi Geng, Feng Li
exaly +3 more sources
Molecular Immunology, 2023
Severe acute pancreatitis (SAP) is a kind of reversible inflammatory process of the exocrine pancreas with gastrointestinal motility dysfunction involved. Studies have highlighted the role of long noncoding RNA metastasis associated lung adenocarcinoma transcript 1 (MALAT1) in AP.
Lixia, Lai +3 more
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Severe acute pancreatitis (SAP) is a kind of reversible inflammatory process of the exocrine pancreas with gastrointestinal motility dysfunction involved. Studies have highlighted the role of long noncoding RNA metastasis associated lung adenocarcinoma transcript 1 (MALAT1) in AP.
Lixia, Lai +3 more
openaire +2 more sources
Toxicology in Vitro, 2017
Estrogen is essential for growth and development of ovarian follicles. Infections associated with E. coli or Endotoxin (LPS) suppress estradiol production by the downregulation of CYP19A1 expression. However, the molecular mechanism of its down regulation is not yet known.
Vengala Rao, Yenuganti +2 more
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Estrogen is essential for growth and development of ovarian follicles. Infections associated with E. coli or Endotoxin (LPS) suppress estradiol production by the downregulation of CYP19A1 expression. However, the molecular mechanism of its down regulation is not yet known.
Vengala Rao, Yenuganti +2 more
openaire +2 more sources
Abstract Temozolomide (TMZ), the primary drug for glioma treatment, has limited treatment efficacy. Additionally, considerable evidence shows that isocitrate dehydrogenase 1 mutation‐type (IDH1 mut) gliomas have a better response to TMZ than isocitrate dehydrogenase 1 wildtype (IDH1 wt) gliomas.
Shuai Wang +4 more
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International Journal of Biological Macromolecules
Major depressive disorder (MDD) is a highly prevalent condition and one of the most common psychiatric disorders worldwide. Circular RNA (circRNA) has been increasingly implicated in MDD. However, a comprehensive understanding of circRNA and microglial apoptosis in depression is incomplete.
Honghong Yao, Zhou zhongqiu, Bing Han
exaly +3 more sources
Major depressive disorder (MDD) is a highly prevalent condition and one of the most common psychiatric disorders worldwide. Circular RNA (circRNA) has been increasingly implicated in MDD. However, a comprehensive understanding of circRNA and microglial apoptosis in depression is incomplete.
Honghong Yao, Zhou zhongqiu, Bing Han
exaly +3 more sources
CEBPB inhibition via miRNA298-5p mediates inflammation in ARDS 3885
The Journal of ImmunologyAbstract Description Acute Respiratory Distress Syndrome (ARDS) poses a significant risk in advanced COVID-19 and other inflammatory conditions. Characterized by damage to the pulmonary endothelium and epithelium, leading to pulmonary edema, hypoxemia, and excessive inflammation.
Jordan Ellette Williams +3 more
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HDAC4 super-enhancer drives CEBPB-mediated TWIST2 transcription to promote chemoresistance in LUAD
Cancer LettersLung cancer remains one of the most prevalent malignancies worldwide. This study investigates the role of histone deacetylase 4 (HDAC4) in mediating chemoresistance in lung adenocarcinoma (LUAD). Super-enhancers (SEs), known to regulate aberrant gene expression, are critical drivers of tumor progression.
Min Jiang +11 more
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A CEBPB/miR-32–5p/GATA6 axis promotes vascular calcification in type 2 diabetes
The International Journal of Biochemistry & Cell BiologyVascular calcification in diabetes patients is a major independent risk factor for developing diabetic cardiovascular complications. However, the mechanisms by which diabetes leads to vascular calcification are complex and not yet fully understood.
Zhibo, Zhao +6 more
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AbstractObjectiveTo explore the biological function and mechanisms of CEBPB and NAT10‐mediated N4‐acetylcytidine (ac4c) modification in salivary adenoid cystic carcinoma (SACC).Materials and MethodsCEBPB and NAT10 were knocked down in SACC–LM cells by siRNA transfection and overexpressed in SACC‐83 cells by plasmid transfection.
Min Fu +5 more
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