Results 51 to 60 of about 44,409 (342)

With mouse age comes wisdom : a review and suggestions of relevant mouse models for age-related conditions [PDF]

, 2016
Ageing is a complex multifactorial process that results in many changes in physiological changes processes that ultimately increase susceptibility to a wide range of diseases.
Barini, Erica, Castro, Rui E, Drechsler, Susanne, González-Navarro, Herminia, Hecimovic, Silva, Lynch, Marina A, Novella, Susana, Osuchowski, Marcin, Potter, Paul K, Tucci, Valter, Vandenbroucke, Roosmarijn   +10 more
core   +2 more sources

Prevalência de helmintíases em apêndices cecais

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: Relatar a prevalência do diagnóstico de helmintíases em apêndices cecais removidos por procedimentos cirúrgicos em municípios do Estado do Rio Grande do Sul e enviados para o Instituto de Patologia de Passo Fundo.
Mirian Beatriz Gehlen Ferrari, Rubens Rodriguez   +1 more
doaj   +1 more source

Ketamine inhibits TNF-α-induced cecal damage by enhancing RIP1 ubiquitination to attenuate lethal SIRS

Cell Death Discovery, 2022
Systemic inflammatory response syndrome (SIRS) is a sepsis-associated inflammatory state and a self-defense mechanism against specific and nonspecific stimuli. Ketamine influences many key processes that are altered during sepsis. However, the underlying
Bin Deng, Daowei Yang, Huanghui Wu, Lu Wang, Rui Wu, Hongrui Zhu, Ailing Huang, Jingyi Song, Tieliang Cai, Shanshan Liu, Jingsi Wu, Huiying Zhou, Chunhui Li   +12 more
doaj   +1 more source

Solitary Cecal Ulcer: A Case Report

Frontiers in Surgery, 2022
BackgroundSolitary cecal ulcer is a rare disease. Its etiology is unknown and there are no pathognomonic symptoms. There are rare reports mimicking carcinoma as seen in this case.Case PresentationA 64 year-old woman presented with a history of ...
Chun Qiang Li, An-Qi He, Gang Liu
doaj   +1 more source

Taurocholic Acid Is Associated With Disturbed Functional Connectivity in the Hippocampus of Patients With Depression

Advanced Science, EarlyView.
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai, Taipeng Sun, Mengzhen Feng, Gang Chen, Junchi Zhou, Hong Zhuang, Dan Wang, Ying Chen, Zhen Cheng, Zhi Xu, Xiao Zheng, Xueli Zhang, Yonggui Yuan   +12 more
wiley   +1 more source

Microenvironment Self‐Adaptive Nanoarmor to Address Adhesion‐ and Colonization‐Related Obstacles in Impaired Intestine Promote Bacteriotherapy Against Parkinson's Disease

Advanced Science, EarlyView.
A microenvironment self‐adaptive nanoarmor is developed to effectively address the adhesion‐ and colonization‐related challenges posed by multiple physiological and pathological characteristics in the intestine. L. plantarum@MPN@CS showed significant therapeutic potential in treating Parkinson's disease (PD), a model for extraintestinal disorders, as ...
Limeng Zhu, Yuyu Wu, Yingjie Chen, Xiyi Chen, Xingjie Zan, Yanlong Liu, Wujun Geng   +6 more
wiley   +1 more source

Eimeria maxima-induced transcriptional changes in the cecal mucosa of broiler chickens

Parasites & Vectors, 2019
Background Apicomplexan protozoans of the genus Eimeria cause coccidiosis, one of the most economically relevant parasitic diseases in chickens. The lack of a complete understanding of molecular mechanisms in the host-parasite interaction limits the ...
Charles Li, Xianghe Yan, Hyun S. Lillehoj, Sungtaek Oh, Liheng Liu, Zhifeng Sun, Changqin Gu, Youngsub Lee, Zhezi Xianyu, Hongyan Zhao   +9 more
doaj   +1 more source

Fecal microbiota transplant rescues mice from human pathogen mediated sepsis by restoring systemic immunity. [PDF]

, 2020
Death due to sepsis remains a persistent threat to critically ill patients confined to the intensive care unit and is characterized by colonization with multi-drug-resistant healthcare-associated pathogens.
Alverdy, John C, Antonopoulos, Dionysios A, Barreiro, Luis B, Bouziat, Romain, Christley, Scott, DeFazio, Jennifer R, Ernest, Jordan D, Fleming, Irma D, Gilbert, Jack A, Harris, Katharine G, Hyoju, Sanjiv K, Jabri, Bana, Keskey, Robert, Khodarev, Nikolai N, Kim, Sangman M, Krezalek, Monika A, Malik, Ankit, Ranoa, Diana R, Sangani, Kishan, Sangwan, Naseer, Shakhsheer, Baddr A, Weichselbaum, Ralph R, Wiegerinck, Mara, Zaborin, Alexander, Zaborina, Olga   +24 more
core  

Immunopathological properties of the Campylobacter jejuni flagellins and the adhesin CadF as assessed in a clinical murine infection model [PDF]

, 2019
Background: Campylobacter jejuni infections constitute serious threats to human health with increasing prevalences worldwide. Our knowledge regarding the molecular mechanisms underlying host-pathogen interactions is still limited.
Backert, Steffen, Bereswill, Stefan, Boehm, Manja, Escher, Ulrike, Heimesaat, Markus M., Mousavi, Soraya, Schmidt, Anna-Maria, Tegtmeyer, Nicole   +7 more
core   +4 more sources

Fermented Lacticaseibacillus Paracasei Cultures Ameliorate Colitis by Modulating Microbiota‐Derived Tryptophan Metabolism and Macrophage Polarization

Advanced Science, EarlyView.
A solid‐state fermented probiotic (PYW) is developed using wheat bran as substrate, containing high viable Lacticaseibacillus paracasei and bioactive metabolites. PYW alleviates intestinal inflammation by gut microbiota composition, enriching indole derivatives, activating aryl hydrocarbon receptor signaling, and regulating macrophage polarization. PYW
Heng Zhang, Jingzhou Sun, Xin Zheng, Huiqing Yang, Aowen Xie, Yuxuan Ding, Yuxia Mei, Jinshan Li, Yuanliang Hu, Min Ren, Yangyang Liu, Yunxiang Liang   +11 more
wiley   +1 more source