Results 71 to 80 of about 42,856 (342)

A Rare Case of Vasculitis Patched Necrosis of Cecum due to Behçet’s Disease

Case Reports in Surgery, 2017
Isolated cecal necrosis is a rare form of acute ischemic colitis and a rare cause of surgical abdomen. Behçet’s disease is a multisystemic autoimmune condition which can induce vasculitis.
Ehsan Shahverdi, Mehdi Morshedi, Faraneh Oraei-Abbasian, Maryam Allahverdi Khani, Roya Khodayarnejad   +4 more
doaj   +1 more source

Salmonella Virchow Infection of the Chicken Elicits Cellular and Humoral Systemic and Mucosal Responses, but Limited Protection to Homologous or Heterologous Re-Challenge. [PDF]

, 2014
Salmonella enterica serovar Virchow usually causes mild gastroenteritis in humans; however, it is frequently invasive and many isolates are resistant to a broad-range of therapeutic antimicrobials.
Anja eKipar, Anja eKipar, Anne-Marie eSalisbury, Gail eLeeming, Georgios eNikolaou, Paul eWigley   +5 more
core   +2 more sources

Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome

Advanced Science, EarlyView.
By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang, Siqi Guo, Jing Li, Qianqian Huang, Jing Ning, Binbin Xia, Xun Lv, Xiang Liu, Zeyu Gao, Jine Li, Longchao Liu, Moshi Song, Jun Wang   +12 more
wiley   +1 more source

“Cat scratch colon” causing cecal perforation as a rare complication due to barotrauma during colonoscopy: A case report and literature review

DEN Open
“Cat scratch colon” (CSC), characterized by spontaneous bright‐red linear markings or mucosal laceration with bleeding due to air insufflation barotrauma, is a rare complication during colonoscopy.
Hitoshi Hara, Yasuhide Muto, Tomoki Kido, Ryohei Miyata, Moe Tokuda, Tomohiro Maesono, Takahiro Ajihara, Takuma Naritomi, Michio Itabashi   +8 more
doaj   +1 more source

Infecções parasitárias do apêndice cecal e suas relações com apendicite aguda Parasitic infection of the appendix and its possible relationship to acute appendicitis

Arquivos de Gastroenterologia, 2008
Investigou-se a prevalência de infecções parasitárias do apêndice cecal e suas relações com a apendicite. Dos 1.600 apêndices estudados 24 (1,5%) apresentaram infecção parasitária. Enterobius vermicularis foi encontrado em 23 casos (95,8%) e Taenia sp em
Danielle Fernandes da Silva, Reinaldo José da Silva, Márcia Guimarães da Silva, Alesso Cervantes Sartorelli, Bonifácio Katsunori Takegawa, Maria Aparecida Marchesan Rodrigues   +5 more
doaj   +1 more source

Hepcidin and Host Defense against Infectious Diseases. [PDF]

, 2015
Hepcidin is the master regulator of iron homeostasis in vertebrates. The synthesis of hepcidin is induced by systemic iron levels and by inflammatory stimuli.
Ganz, Tomas, Mehrad, Borna, Michels, Kathryn, Nemeth, Elizabeta   +3 more
core   +1 more source

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

Advanced Science, EarlyView.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu, Yaqian Cui, Yongqiang Zhou, Yihui Zheng, Lijiang Huang, Leiming Jin, Qianhui Zhang, Pan Chen, Mengsha Lin, Jiaxi Ye, Yongqiang Xiong, Joo Young Huh, Xiang Hu, Xiaokun Li, Wu Luo, Guang Liang   +15 more
wiley   +1 more source

EEPD1 Inhibition Unleashes Antitumor Immunity in Colorectal Cancer by Activating the cGAS‐STING Pathway

Advanced Science, EarlyView.
In colorectal cancer, high expression of the DNA repair protein EEPD1 correlates with immune exclusion and poor prognosis. This study demonstrates that EEPD1 depletion induces genomic instability, leading to cytosolic DNA accumulation and subsequent activation of the cGAS‐STING‐type I interferon pathway. This cascade remodels the tumor microenvironment
Liyun Huo, Chong Wu, Xiaobo Li, Caina Ma, Jiamin Huang, Zishuo Chen, Weiling He, Tianyu Tao, Weijing Zhang   +8 more
wiley   +1 more source

Pasture intake protects against commercial diet-induced lipopolysaccharide production facilitated by gut microbiota through activating intestinal alkaline phosphatase enzyme in meat geese

Frontiers in Immunology, 2022
IntroductionDiet strongly affects gut microbiota composition, and gut bacteria can influence the intestinal barrier functions and systemic inflammation through metabolic endotoxemia.
Qasim Ali, Sen Ma, Sen Ma, Sen Ma, Umar Farooq, Jiakuan Niu, Fen Li, Defeng Li, Defeng Li, Defeng Li, Zhichang Wang, Zhichang Wang, Zhichang Wang, Hao Sun, Hao Sun, Hao Sun, Yalei Cui, Yalei Cui, Yalei Cui, Yinghua Shi, Yinghua Shi, Yinghua Shi   +21 more
doaj   +1 more source

A Synergistic Hydrogel‐Microalgae Platform for Dual‐Targeting of Intestinal and Neuroimmune Dysfunction in Inflammatory Bowel Disease

Advanced Science, EarlyView.
A bioactive hydrogel incorporating Chlorella vulgaris and paeoniflorin within a carboxymethyl chitosan/sodium alginate matrix cross‐linked with genipin is developed for inflammatory bowel disease therapy. The hydrogel exhibits gastric stability and intestine‐responsive release.
Jing Lu, Kangyu Jin, Bing Chen, Ruoxi Wang, Fengling Hu, Shaohua Hu, Danni Zhong, Xiaoming Li, Min Zhou   +8 more
wiley   +1 more source