Intradermal testing increases the accuracy of an immediate-type cefaclor hypersensitivity diagnosis
Background: Hypersensitivity reactions to cefaclor have increased in accordance with its frequent use. However, only limited data are available on the diagnostic value of skin tests for these conditions, particularly intradermal tests (IDTs).
Ji-Hyang Lee, MD, PhD +9 more
doaj +1 more source
We conducted a phase I bioequivalence trial in healthy Chinese subjects in the fasting and postprandial states. The goal of this trial was to compare the pharmacokinetics and safety of the test preparation Cefaclor granule (Disha Pharmaceutical Group Co.,
Xinyao Qu +15 more
doaj +1 more source
Antibiotic Prescribing for Cellulitis in the Absence of Penicillin-Cephalosporin Cross-Reactivity Alerts: A Retrospective Study. [PDF]
ABSTRACT Cephalosporins are often avoided in patients with penicillin adverse drug reaction (ADR) labels. In our institution's electronic medication management system, penicillin and cephalosporin ADR labels do not generate cross‐reactivity alerts. Penicillins and cephalosporins are preferred treatments for cellulitis.
Sundermann M +5 more
europepmc +2 more sources
Cefaclor causes vagus nerve-mediated depression-like symptoms with gut dysbiosis in mice
Antibiotics are increasingly recognized as causing neuropsychiatric side effects including depression and anxiety. Alterations in central serotonin and 5-HT receptor expression are implicated in the pathogenesis of anxiety and depression, which are ...
Min-Kyung Joo +2 more
doaj +1 more source
Comparative Evaluation of Antibacterial Efficacy and Microhardness after Adding Different Combinations of Triple Antibiotic Powder in Conventional Restorative Glass Ionomer Cement [PDF]
Introduction: Atraumatic Restorative Treatment (ART) use only hand instruments for caries removal therefore bacteria may remain and survive underneath these restorations. This problem can be solved if the restorative material also possesses antibacterial
Pradnya Ramkrishna Chaudhari +7 more
doaj +1 more source
Case: Unexpected development of severe penicillin allergy and review of literature
A 54‐year‐old man developed a severe anaphylactic penicillin allergy after 16 years and 5 standard erysipelas treatments by intravenous benzylpenicillin and/or oral phenoxymethylpenicillin without any symptoms of allergy.
Rauno J. Harvima, Ilkka T. Harvima
doaj +1 more source
Cephalexin and Cefaclor, are widely prescribed antibiotics known for their characteristic bitter taste. This bitterness is attributed to the specific chemical composition of these substances. The sensory experience of bitterness is influenced by distinct
Diyar B. Wso +1 more
doaj +1 more source
This case-non-case study aims to detect signals not currently listed on cephalosporin drug labels. From 2009 to 2018, adverse event (AE) reports concerning antibacterial drugs (anatomical therapeutic chemical (ATC) code J01) in the Korea Adverse Events ...
Jung-Yoon Choi +3 more
doaj +1 more source
Evaluating Effects of Antibiotics Across Preclinical Models of the Human Gastrointestinal Microbiota. [PDF]
We compared microbiota changes following antibiotic treatment in two preclinical models of the human GI microbiota, minibioreactor arrays (MBRAs) and human microbiota associated mice (HMAmice). MBRAs and HMAmice were colonized with feces from 12 or 3 healthy humans, respectively, before treatment with each of 12 or 6 antibiotics.
Auchtung TA +3 more
europepmc +2 more sources
Facile one-pot synthesis of amoxicillin-coated gold nanoparticles and their antimicrobial activity [PDF]
Nanomaterials have been the object of intense study due to promising applications in a number of different disciplines. In particular, medicine and biology have seen the potential of these novel materials with their nanoscale properties for use in ...
A Fleming +19 more
core +1 more source

