Results 11 to 20 of about 7,797 (210)

Intradermal testing increases the accuracy of an immediate-type cefaclor hypersensitivity diagnosis

open access: yesWorld Allergy Organization Journal, 2022
Background: Hypersensitivity reactions to cefaclor have increased in accordance with its frequent use. However, only limited data are available on the diagnostic value of skin tests for these conditions, particularly intradermal tests (IDTs).
Ji-Hyang Lee, MD, PhD   +9 more
doaj   +1 more source

Pharmacokinetics and safety of the two oral cefaclor formulations in healthy chinese subjects in the fasting and postprandial states

open access: yesFrontiers in Pharmacology, 2022
We conducted a phase I bioequivalence trial in healthy Chinese subjects in the fasting and postprandial states. The goal of this trial was to compare the pharmacokinetics and safety of the test preparation Cefaclor granule (Disha Pharmaceutical Group Co.,
Xinyao Qu   +15 more
doaj   +1 more source

Antibiotic Prescribing for Cellulitis in the Absence of Penicillin-Cephalosporin Cross-Reactivity Alerts: A Retrospective Study. [PDF]

open access: yesPharmacol Res Perspect
ABSTRACT Cephalosporins are often avoided in patients with penicillin adverse drug reaction (ADR) labels. In our institution's electronic medication management system, penicillin and cephalosporin ADR labels do not generate cross‐reactivity alerts. Penicillins and cephalosporins are preferred treatments for cellulitis.
Sundermann M   +5 more
europepmc   +2 more sources

Cefaclor causes vagus nerve-mediated depression-like symptoms with gut dysbiosis in mice

open access: yesScientific Reports, 2023
Antibiotics are increasingly recognized as causing neuropsychiatric side effects including depression and anxiety. Alterations in central serotonin and 5-HT receptor expression are implicated in the pathogenesis of anxiety and depression, which are ...
Min-Kyung Joo   +2 more
doaj   +1 more source

Comparative Evaluation of Antibacterial Efficacy and Microhardness after Adding Different Combinations of Triple Antibiotic Powder in Conventional Restorative Glass Ionomer Cement [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2020
Introduction: Atraumatic Restorative Treatment (ART) use only hand instruments for caries removal therefore bacteria may remain and survive underneath these restorations. This problem can be solved if the restorative material also possesses antibacterial
Pradnya Ramkrishna Chaudhari   +7 more
doaj   +1 more source

Case: Unexpected development of severe penicillin allergy and review of literature

open access: yesClinical Case Reports, 2022
A 54‐year‐old man developed a severe anaphylactic penicillin allergy after 16 years and 5 standard erysipelas treatments by intravenous benzylpenicillin and/or oral phenoxymethylpenicillin without any symptoms of allergy.
Rauno J. Harvima, Ilkka T. Harvima
doaj   +1 more source

Evaluating the Effect of Primary Amine in Bitterness of Selected Cephalosporins Cephalexin and Cefaclor as Examples

open access: yesPolytechnic Journal, 2023
Cephalexin and Cefaclor, are widely prescribed antibiotics known for their characteristic bitter taste. This bitterness is attributed to the specific chemical composition of these substances. The sensory experience of bitterness is influenced by distinct
Diyar B. Wso   +1 more
doaj   +1 more source

Signal Detection of Adverse Drug Reactions of Cephalosporins Using Data from a National Pharmacovigilance Database

open access: yesPharmaceuticals, 2021
This case-non-case study aims to detect signals not currently listed on cephalosporin drug labels. From 2009 to 2018, adverse event (AE) reports concerning antibacterial drugs (anatomical therapeutic chemical (ATC) code J01) in the Korea Adverse Events ...
Jung-Yoon Choi   +3 more
doaj   +1 more source

Evaluating Effects of Antibiotics Across Preclinical Models of the Human Gastrointestinal Microbiota. [PDF]

open access: yesMicrobiologyopen
We compared microbiota changes following antibiotic treatment in two preclinical models of the human GI microbiota, minibioreactor arrays (MBRAs) and human microbiota associated mice (HMAmice). MBRAs and HMAmice were colonized with feces from 12 or 3 healthy humans, respectively, before treatment with each of 12 or 6 antibiotics.
Auchtung TA   +3 more
europepmc   +2 more sources

Facile one-pot synthesis of amoxicillin-coated gold nanoparticles and their antimicrobial activity [PDF]

open access: yes, 2014
Nanomaterials have been the object of intense study due to promising applications in a number of different disciplines. In particular, medicine and biology have seen the potential of these novel materials with their nanoscale properties for use in ...
A Fleming   +19 more
core   +1 more source

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