Results 81 to 90 of about 49,161 (205)
ABSTRACT Background and Aims Urinary tract infections (UTIs) are prevalent among adolescent girls. Therefore, effective promotional campaigns are crucial for conveying accurate information. This study aimed to assess the prevalence and the antimicrobial profiling of the isolated uropathogens among 354 adolescent girls. Methods This is a cross‐sectional
Shimaa Abdelrahim Khalaf +5 more
wiley +1 more source
Cefepime Neurotoxicity in an Adolescent Cystic Fibrosis Patient with Aminoglycoside-Induced Acute Kidney Injury [PDF]
Objective: To describe a case of cefepime neurotoxicity in an adolescent with cystic fibrosis and aminoglycoside-associated acute kidney injury (AKI). Case Summary: A 15-year-old, 46-kg male with cystic fibrosis (CF) and chronic sinusitis was admitted ...
Andreoli, Sharon P. +3 more
core +2 more sources
Mitochondrial Dysfunction in Propionic Acidemia: A Case‐Report and Review of the Literature
ABSTRACT Propionic acidemia is an inborn error of metabolism involving an enzymatic defect of propionyl‐CoA carboxylase that results in the build‐up of toxic metabolites which can induce metabolic decompensation. Secondary mitochondrial dysfunction in propionic acidemia has been commonly recognized; however, its clinical presentation and management are
Brandon K. Walther +5 more
wiley +1 more source
ABSTRACT Cefepime, a broad‐spectrum fourth‐generation cephalosporin, is widely used to treat nosocomial infections. Dependence upon renal elimination makes its pharmacokinetics highly susceptible to changes in renal function, which are common in critically ill patients.
Maged Kharouba +5 more
wiley +1 more source
Cefepime, uma cefalosporina de quarta geração, com amplo espectro de ação, é um antibiótico largamente utilizado no tratamento de infecções graves em ambientes hospitalares. O registro de segurança deste fármaco é considerado favorável.
José Augusto Bragatti +3 more
doaj +1 more source
Potential of high-dose cefepime/tazobactam against multi-resistant Gram-negative pathogens [PDF]
Background: Early β-lactamase inhibitors were combined with established penicillins, but different combinations may be more appropriate to counter current β-lactamase threats, with development facilitated by the US Generating Antibiotic Incentives Now ...
Livermore, David M +4 more
core +1 more source
Summary Febrile neutropenia causes substantial morbidity in acute myeloid leukaemia and higher risk myelodysplastic syndrome. We aimed to describe current practice and priorities for clinical trials in the prevention and management of febrile neutropenia across Australia/New Zealand (ANZ), the United Kingdom (UK), Canada and Europe.
Aleece MacPhail +14 more
wiley +1 more source
Molecular basis of antibiotic sensing by the TetR family regulator CecR – a structural perspective
Escherichia coli CecR, a member of the TetR family regulators, senses selected antibiotics and activates the expression of a putative drug efflux pump. Although present in many pathogenic Enterobacteriales strains, CecR remains poorly characterized. We present the first CecR crystal structure, which reveals a unique tunnel‐like ligand‐binding cavity ...
Agnieszka J. Pietrzyk‐Brzezinska +5 more
wiley +1 more source
Cefepime-Induced Neutropenia: A Case Report and Literature Review
Somaya Koraysh,1 Junais Koleri,2 Maisa Ali2 1Department of Pharmacy, Hamad Bin Khalifa Medical City, Hamad Medical Corporation, Doha, Qatar; 2Department of Infectious Disease, Communicable Disease Center, Hamad Medical Corporation, Doha ...
Koraysh S, Koleri J, Ali M
doaj
Malignant Otitis Externa in Central Australia: A 15‐Year Retrospective Review Between 2009 and 2024
ABSTRACT We performed a 15‐year retrospective audit of all cases of malignant otitis externa (MOE) referred to Alice Springs Hospital in Central Australia from 2009 to 2024, the largest Australian series of MOE. Data on demographics, risk factors, microbiological culture results, management and outcomes were collected, identifying 64 cases of MOE, with
George P. Drewett +6 more
wiley +1 more source

