Cephem Potentiation by Inactivation of Nonessential Genes Involved in Cell Wall Biogenesis of ß-Lactamase-Producing Escherichia coli [PDF]
Reversal of antimicrobial resistance is an appealing and largely unexplored strategy in drug discovery. The objective of this study was to identify potential targets for “helper” drugs reversing cephem resistance in Escherichia coli strains producing β ...
Baker, K R +3 more
core +2 more sources
Evaluating Prescriber Adherence to Guideline-Based Treatment Pathways of a Newly Initiated Antimicrobial Stewardship Program at a Rehabilitation Hospital [PDF]
Background: Inappropriate use of antimicrobials in the healthcare setting is associated with consequences including antimicrobial resistance, Clostridium difficile infection (CDI), adverse drug reactions, and increased healthcare costs.
Bertram, Christie
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Development of acute kidney injury with concomitant use of Vancomycin and Piperacillin-Tasobactam : A review of recent literature [PDF]
This article explores the potential association between co-administration of vancomycin and piperacillin-tazobactam with the development of acute kidney injury (AKI) when compared with vancomycin and other beta lactam antibiotics or vancomycin ...
Gruss, Jason +3 more
core +1 more source
Cefepime, uma cefalosporina de quarta geração, com amplo espectro de ação, é um antibiótico largamente utilizado no tratamento de infecções graves em ambientes hospitalares. O registro de segurança deste fármaco é considerado favorável.
José Augusto Bragatti +3 more
doaj +1 more source
Antimicrobial susceptibility pattern and multidrug resistance ındex in Pseudomonas aeruginosa among clinical isolates in Denizli, Turkey [PDF]
Background: Pseudomonas aeruginosa is an important hospital infection agent causing morbidity and mortality with the ability to gain resistance to many antimicrobials. The objective of this study was to determine the sensitivity profiles of nosocomial P.
Keskin, D., Kıraç, Selma, Yarar, M.
core +2 more sources
ObjectiveThis study aimed to evaluate the real-world clinical efficacy and safety of cefepime in treating pediatric community-acquired pneumonia (CAP), comparing it with other broad-spectrum antibiotics, including cefoperazone-sulbactam and meropenem ...
Changxin Liu +6 more
doaj +1 more source
Results of A Local Combination Therapy Antibiogram For \u3cem\u3ePseudomonas Aeruginosa\u3c/em\u3e Isolates: Is Double Worth The Trouble? [PDF]
Purpose: To determine the frequency at which fluoroquinolones and aminoglycosides demonstrate in vitro activity against non-urinary, non-skin/skin structure Pseudomonas aeruginosa isolates exhibiting decreased susceptibilities to one or more β-lactam ...
Davis, Jim +4 more
core +1 more source
Implementing Extended-Infusion Cefepime as Standard of Care in a Children’s Hospital: A Prospective Descriptive Study [PDF]
Background: Extended-infusion cefepime (EIC) has been associated with decreased mortality in adults, but to our knowledge, there are no studies in children.
Cox, Elaine G. +4 more
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Cefepime-Induced Neutropenia: A Case Report and Literature Review
Somaya Koraysh,1 Junais Koleri,2 Maisa Ali2 1Department of Pharmacy, Hamad Bin Khalifa Medical City, Hamad Medical Corporation, Doha, Qatar; 2Department of Infectious Disease, Communicable Disease Center, Hamad Medical Corporation, Doha ...
Koraysh S, Koleri J, Ali M
doaj
Comparison of patient outcomes in a pharmacist-led outpatient parenteral antimicrobial therapy program [PDF]
Purpose: Outpatient parenteral antimicrobial therapy (OPAT) is a therapeutic option meant to conserve healthcare resources when treating infections requiring the administration of IV antibiotics over a prolonged treatment course.
Howe, Zachary
core +1 more source

