Results 31 to 40 of about 14,396 (200)

Evaluating the in vitro activity of cefoperazone-sulbactam against Gram negative pathogens in blood stream infections using automated systems [PDF]

open access: yesIranian Journal of Microbiology
Background and Objectives: The incidence of multidrug-resistant, Gram-negative organisms, isolated as the etiological agents of infections is ascending.
Uksim Qadri   +6 more
doaj   +2 more sources

Perioperative antibiotic prophylaxis in surgery

open access: yesPerioperative Medicine, 2021
Infectious complications in surgery occupy a significant place among the causes of death and increase in the cost of medical care for various pathologies.
Dmytro Dmytriiev   +2 more
doaj   +1 more source

Case Report: Drug-Induced Immune Haemolytic Anaemia Caused by Cefoperazone-Tazobactam/ Sulbactam Combination Therapy

open access: yesFrontiers in Medicine, 2021
There has previously been a report of a patient developing haemolytic anaemia following exposure to cefoperazone. Another case has been reported involving the detection of cefoperazone-dependent antibodies in the absence of immune haemolytic anaemia.
Yuanjun Wu   +7 more
doaj   +1 more source

Retrospective Analysis of Risk Factors for Cefoperazone/Sulbactam-Induced Thrombocytopenia in Adult Chinese Patients: A Six-Year Real-World Study [PDF]

open access: yesInfection and Drug Resistance
Bolin Zhu, Pengfei Jin, Jianchun Li, Yuanchao Zhu Department of Pharmacy, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing Key Laboratory of Assessment of Clinical Drugs Risk ...
Zhu B, Jin P, Li J, Zhu Y
doaj   +1 more source

Cefoperazone Induced Gastrointestinal Bleeding [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Cefoperazone is a beta-lactam antibiotic which is frequently used in treating a variety of gram positive and gram negative infections. The chemical structure of cefoperazone contains a side chain of N-methylthiotetrazole which can inhibit vitamin K ...
Goutham Reddy Katukuri   +3 more
doaj   +1 more source

Model-Informed Drug Development of New Cefoperazone Sodium and Sulbactam Sodium Combination (3:1): Pharmacokinetic/Pharmacodynamic Analysis and Antibacterial Efficacy Against Enterobacteriaceae

open access: yesFrontiers in Pharmacology, 2022
Objective: Cefoperazone/sulbactam is a commonly used antibiotic combination against the extended-spectrum beta-lactamases (ESBLs)-producing bacteria. The objective of this study was to evaluate the efficacy of a new cefoperazone/sulbactam combination (3 ...
Xi-Wei Ji   +10 more
doaj   +1 more source

RATIONAL USE OF 3rd GENERATION CEPHALOSPORINS IN TERTIARY CARE HOSPITALS: A CONCURRENT DUR

open access: yesInternational Journal of Pharmacy & Integrated Health Sciences, 2022
Background: Assessment of use of antimicrobials can be performed by evaluating their use. Drug use evaluation is a performance improvement method that concentrates on improvement and evaluation of drug use processes to achieve optimal patient outcomes.
doaj   +1 more source

Combined PK/PD Index May Be a More Appropriate PK/PD Index for Cefoperazone/Sulbactam against Acinetobacter baumannii in Patients with Hospital-Acquired Pneumonia

open access: yesAntibiotics, 2022
Cefoperazone/sulbactam (CPZ/SUL) is a β-lactam and β-lactamase inhibitor combination therapy for the treatment of respiratory tract infections. Using data from a prospective, multiple-center, open-label clinical trial in 54 patients with hospital ...
Yingjie Zhou   +9 more
doaj   +1 more source

In vitro evaluation of cefoperazone [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 1980
The activity of cefoperazone, a new broad-spectrum cephalosporin, was tested in vitro against 670 clinical isolates of gram-negative bacilli and gram-positive cocci. With the exception of Enterobacter spp., it inhibited the majority of all organisms tested at a concentration of 6.25 microgram/ml.
A M, Hinkle, B M, LeBlanc, G P, Bodey
openaire   +2 more sources

Comparison of Tigecycline or Cefoperazone/Sulbactam therapy for bloodstream infection due to Carbapenem-resistant Acinetobacter baumannii

open access: yesAntimicrobial Resistance and Infection Control, 2019
Background We retrospectively analyzed the effect of tigecycline and cefoperazone/sulbactam therapies on the prognosis of patients with carbapenem-resistant Acinetobacter baumannii bloodstream infection (CRAB-BSI).
Tianshui Niu   +5 more
doaj   +1 more source

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