Results 21 to 30 of about 13,451 (203)

Model-Informed Drug Development of New Cefoperazone Sodium and Sulbactam Sodium Combination (3:1): Pharmacokinetic/Pharmacodynamic Analysis and Antibacterial Efficacy Against Enterobacteriaceae

open access: yesFrontiers in Pharmacology, 2022
Objective: Cefoperazone/sulbactam is a commonly used antibiotic combination against the extended-spectrum beta-lactamases (ESBLs)-producing bacteria. The objective of this study was to evaluate the efficacy of a new cefoperazone/sulbactam combination (3 ...
Xi-Wei Ji   +10 more
doaj   +1 more source

RATIONAL USE OF 3rd GENERATION CEPHALOSPORINS IN TERTIARY CARE HOSPITALS: A CONCURRENT DUR

open access: yesInternational Journal of Pharmacy & Integrated Health Sciences, 2022
Background: Assessment of use of antimicrobials can be performed by evaluating their use. Drug use evaluation is a performance improvement method that concentrates on improvement and evaluation of drug use processes to achieve optimal patient outcomes.
doaj   +1 more source

Combined PK/PD Index May Be a More Appropriate PK/PD Index for Cefoperazone/Sulbactam against Acinetobacter baumannii in Patients with Hospital-Acquired Pneumonia

open access: yesAntibiotics, 2022
Cefoperazone/sulbactam (CPZ/SUL) is a β-lactam and β-lactamase inhibitor combination therapy for the treatment of respiratory tract infections. Using data from a prospective, multiple-center, open-label clinical trial in 54 patients with hospital ...
Yingjie Zhou   +9 more
doaj   +1 more source

Quorum Sensing Inhibiting Activity of Cefoperazone and Its Metallic Derivatives on Pseudomonas aeruginosa

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
The last decade has witnessed a massive increase in the rate of mortalities caused by multidrug-resistant Pseudomonas aeruginosa. Therefore, developing new strategies to control virulence factors and pathogenicity has received much attention.
Nourhan G. Naga   +4 more
doaj   +1 more source

Cefoperazone metal complexes and their antimicrobial investigations

open access: yesJournal of the Turkish Chemical Society, Section A: Chemistry, 2021
Transition metal (Cd(II), Co(II), Cu(II), Fe(III), Ni(II), Pd(II), Pt(II), Ru(III), Zn(II)) complexes of cefoperazone (CFP) were synthesized and their spectroscopic (IR, UV-Vis), magnetic, thermal (DTA-TG) and mass investigations were conducted to ...
Mehmet Emin ÇINAR   +2 more
doaj   +1 more source

Economic Examination of Cefoperazone Therapy [PDF]

open access: yes, 1987
Medical records of 1137 patients from 35 hospitals were reviewed to examine the total cost of care for patients receiving cefoperazone as initial therapy compared to a control group receiving alternative agents.
Susan Wyant, Jake Jacobs
core   +1 more source

Comparison of Tigecycline or Cefoperazone/Sulbactam therapy for bloodstream infection due to Carbapenem-resistant Acinetobacter baumannii

open access: yesAntimicrobial Resistance and Infection Control, 2019
Background We retrospectively analyzed the effect of tigecycline and cefoperazone/sulbactam therapies on the prognosis of patients with carbapenem-resistant Acinetobacter baumannii bloodstream infection (CRAB-BSI).
Tianshui Niu   +5 more
doaj   +1 more source

Cefoperazone and sulbactam-related eosinophilic peritonitis: a case report and literature review

open access: yesJournal of International Medical Research, 2021
Eosinophilic peritonitis (EP) is a well-described complication of peritoneal dialysis that occurs because of an overreaction to constituents that are related to the catheter or tubing, peritoneal dialysate, pathogenic infection, or intraperitoneal drug ...
Zi Wang   +6 more
doaj   +1 more source

In vitro evaluation of cefoperazone [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 1980
The activity of cefoperazone, a new broad-spectrum cephalosporin, was tested in vitro against 670 clinical isolates of gram-negative bacilli and gram-positive cocci. With the exception of Enterobacter spp., it inhibited the majority of all organisms tested at a concentration of 6.25 microgram/ml.
A M, Hinkle, B M, LeBlanc, G P, Bodey
openaire   +2 more sources

Pharmacokinetics of cefaronide, ceftriaxone and cefoperazone in sheep [PDF]

open access: yes, 1985
Guerrini, V.H., Filippich, L.J., Cao, G.R., English, P.B. & Bourne, D.W.A. Pharmacokinetics of cefaronide, ceftriaxone and cefoperazone in sheep. J. vet. Pharmacol. Therap. 8, 120–127.
CAO, G. R.   +9 more
core   +1 more source

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