Objectives: To evaluate the antimicrobial activities of cefoperazone-sulbactam and comparator agents tested against a large collection of clinical isolates of Gram-negative organisms. Methods: A total of 19 545 Gram-negative organisms were collected from
Helio Sader +2 more
exaly +3 more sources
Comparative pharmacokinetics of cefoperazone following intravenous and intramuscular administration in goats [PDF]
The pharmacokinetic profile of cefoperazone was studied in goats following intravenous and intramuscular administration of 20 mg/kg body weight. Cefoperazone concentrations in serum were determined by microbiological assay technique using Escherichia ...
Taha Attia +4 more
doaj +2 more sources
Comparative analysis of cefoperazone-sulbactam and piperacillin-tazobactam in empirical treatment of acute biliary tract infections: a multicenter, retrospective, real-world study [PDF]
Patients diagnosed with acute cholecystitis or cholangitis admitted to three tertiary Grade A hospitals between January 2022 and March 2026 were enrolled.
Lixing Yang +5 more
doaj +2 more sources
Severe delayed coagulopathy caused by cefoperazone/sulbactam: A case report
This case report described a suspected severe coagulopathy attributed to cefoperazone/sulbactam, and this adverse reaction might be associated with the inhibition of the vitamin K cycle by cefoperazone/sulbactam, leading to vitamin K deficiency within ...
Siqin Sun +4 more
doaj +2 more sources
Cefoperazone induced hypersensitivity vasculitis
Cefoperazone has been reported to cause vasculitic complications only once before. Here, we report yet another case of hypersensitivity vasculitis associated with cefoperazone.
Katiyar Subodh, Prakash Shivesh
doaj +1 more source
Vibrational Analysis and Concentration Dependent SERS Study of Cefoperazone
Cefoperazone is a broad-spectrum antibiotic that is extremely efficient in the treatment of respiratory, abdominal, or genital infections. Vibrational spectroscopic techniques, FT-IR, Raman, and SERS, along with DFT calculations, were involved in ...
Stefana Ana-Maria Faur +3 more
doaj +2 more sources
Adsorptive Cathodic Stripping Voltammetric Determination of Cefoperazone in Bulk Powder, Pharmaceutical Dosage Forms, and Human Urine [PDF]
The electroreduction behaviour and determination of cefoperazone using a hanging mercury drop electrode were investigated. Cyclic voltammograms of cefoperazone recorded in universal Britton-Robinson buffers pH 3–6 exhibited a single irreversible cathodic
Vu Dang Hoang +2 more
doaj +2 more sources
Triggering SORL1 Expression Restricts ccRCC Progression by Inducing Ubiquitination-Mediated c-Myc Degradation. [PDF]
Targeted triggering of SORL1 expression through a novel MPOC delivery system could inhibit ccRCC progression through binding to TRIM22 and further promoting ubiquitination‐mediated C‐MYC degradation, thereby facilitating the inhibition of oxidative phosphorylation through transcriptional repression of ACO2 and IDH2.
Wang K +11 more
europepmc +2 more sources
Chih-Cheng Lai,1 Chi-Chung Chen,2,3 Ying-Chen Lu,3 Yin-Ching Chuang,2,4 Hung-Jen Tang5,6 1Department of Intensive Care Medicine, Chi Mei Medical Center, Liouying, Tainan, Taiwan; 2Department of Medical Research, Chi Mei Medical Center, Tainan, Taiwan ...
Lai CC +4 more
doaj +1 more source
Objectives The mechanism of cefoperazone/sulbactam-induced epilepsy in chronic kidney disease (CKD) patients is not yet clear. We hypothesized that cefoperazone/sulbactam-induced epilepsy could be based on two main factors: neurotoxicity caused by drug ...
Yulu Wu +4 more
doaj +2 more sources

