Results 1 to 10 of about 17,954 (213)

Evaluating the Risk of Coagulopathy in Cephalosporins with Different Side Chains: A Propensity Score–Weighted Study [PDF]

open access: yesMedicina
Background and Objectives: Cephalosporins containing N-hydroxyethyltetrazolethiol (HTT) or N-methylthiotetrazole (NMTT) side chains, such as flomoxef and cefoperazone, have been linked to coagulation abnormalities.
Chien-Hsiang Tai   +2 more
doaj   +2 more sources

Genetic and clinical determinants of tacrolimus accumulation in early liver transplantation: evidence for a combined genotype-antibiotic effect [PDF]

open access: yesAnnals of Medicine
Background Tacrolimus is a first-line immunosuppressant essential for preventing graft rejection after liver transplantation, but its narrow therapeutic index and extensive interindividual pharmacokinetic variability complicate optimal dosing during the ...
Jinlin Guo   +6 more
doaj   +2 more sources

Case Report: Drug-Induced Immune Haemolytic Anaemia Caused by Cefoperazone-Tazobactam/ Sulbactam Combination Therapy

open access: yesFrontiers in Medicine, 2021
There has previously been a report of a patient developing haemolytic anaemia following exposure to cefoperazone. Another case has been reported involving the detection of cefoperazone-dependent antibodies in the absence of immune haemolytic anaemia.
Yuanjun Wu
exaly   +3 more sources

The impact of inoculum size on the activity of cefoperazone-sulbactam against multidrug resistant organisms

open access: yesJournal of Microbiology, Immunology and Infection, 2018
Objectives: This study aims to assess the in vitro activity of cefoperazone alone and different cefoperazone-sulbactam ratios against different inoculum sizes of multidrug resistant organisms.
Chi-Chung Chen   +2 more
exaly   +3 more sources

Severe delayed coagulopathy caused by cefoperazone/sulbactam: A case report [PDF]

open access: yesJournal of International Medical Research
This case report described a suspected severe coagulopathy attributed to cefoperazone/sulbactam, and this adverse reaction might be associated with the inhibition of the vitamin K cycle by cefoperazone/sulbactam, leading to vitamin K deficiency within ...
Siqin Sun   +4 more
doaj   +2 more sources

Antimicrobial activity of cefoperazone-sulbactam tested against Gram-Negative organisms from Europe, Asia-Pacific, and Latin America

open access: yesInternational Journal of Infectious Diseases, 2020
Objectives: To evaluate the antimicrobial activities of cefoperazone-sulbactam and comparator agents tested against a large collection of clinical isolates of Gram-negative organisms. Methods: A total of 19 545 Gram-negative organisms were collected from
Helio S Sader   +2 more
exaly   +3 more sources

Comparative pharmacokinetics of cefoperazone following intravenous and intramuscular administration in goats

open access: yesInternational Journal of Veterinary Science and Medicine, 2015
The pharmacokinetic profile of cefoperazone was studied in goats following intravenous and intramuscular administration of 20 mg/kg body weight. Cefoperazone concentrations in serum were determined by microbiological assay technique using Escherichia ...
Taha Attia   +4 more
exaly   +3 more sources

Case Report: Anaphylactic shock induced by cefoperazone sodium and sulbactam sodium for injection [PDF]

open access: yesFrontiers in Medicine
RationaleCefoperazone-sulbactam is a widely used antibiotic in clinical practice, and anaphylactic shock is a severe adverse drug reaction. Previous literature has rarely reported cases of anaphylactic shock induced by cefoperazone-sulbactam.Patient ...
Weiqian Liu   +8 more
doaj   +2 more sources

Cefoperazone Induced Gastrointestinal Bleeding [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Cefoperazone is a beta-lactam antibiotic which is frequently used in treating a variety of gram positive and gram negative infections. The chemical structure of cefoperazone contains a side chain of N-methylthiotetrazole which can inhibit vitamin K ...
Goutham Reddy Katukuri   +3 more
doaj   +1 more source

Perioperative antibiotic prophylaxis in surgery

open access: yesPerioperative Medicine, 2021
Infectious complications in surgery occupy a significant place among the causes of death and increase in the cost of medical care for various pathologies.
Dmytro Dmytriiev   +2 more
doaj   +1 more source

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