Results 71 to 80 of about 14,396 (200)

Comparative Effect on Levels of C-Reactive Protein (CRP) and Other Inflammatory Markers by Empirical Antibiotic Therapy – A Prospective Observational Study [PDF]

open access: yesJournal of Liaquat National Hospital
Background: Burns trigger a vigorous inflammatory response to injury, which involves the release of various inflammatory mediators and the migration of inflammatory cells to the site of injury. Post-burn infection is also a significant issue. Objective:
Sadaf Pervaiz   +2 more
doaj   +1 more source

In vitro antibacterial effect of probiotics against Carbapenamase-producing multidrug-resistant Klebsiella pneumoniae clinical isolates, Cairo, Egypt

open access: yesJournal of the Egyptian Public Health Association, 2022
Background Searching for a non-antibiotic therapeutic option such as probiotics is gaining momentum nowadays. We aimed to evaluate the in vitro antibacterial ability of cell-free supernatant (CFS) of selected Lactobacillus strains (with probiotic ...
Mona Mohiedden Abdelhalim   +3 more
doaj   +1 more source

Application of Metagenomic Next‐Generation Sequencing in the Diagnosis of Pneumonia in Patients With Cancer

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background With the development of new sequencing technologies, metagenomic next‐generation sequencing (mNGS) has become a diagnostic tool for respiratory tract infections. Patients with cancer may develop pneumonia caused by infections or antitumor therapy.
Rong Qin   +4 more
wiley   +1 more source

EVALUATION OF CEFOPERAZONE/SULBACTAM AND VITAMIN K USE IN PATIENTS WITH BACTERIAL INFECTIONS [PDF]

open access: yes, 2019
Objective: The objectives of this study were to evaluate the effects of Vitamin K use for bleeding or coagulopathies prevention and to assess theoccurrence of drug-related problems in patients receiving cefoperazone/sulbactam.Methods: The prospective ...
SEESIN, THEERAPONG   +5 more
core   +1 more source

Identification of a Novel De Novo Heterozygous SEC61A1 Variant in a Patient With Severe Congenital Neutropenia

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 5, May 2026.
Severe congenital neutropenia can be caused by rare SEC61A1 variants. We report a child with SCN showing granulocytic maturation arrest and abnormal immunophenotype, carrying a novel de novo SEC61A1 p.Trp379Arg variant, expanding the phenotypic and genetic spectrum of SEC61A1‐associated SCN.
Zixuan Wang   +4 more
wiley   +1 more source

Isolation, Identification and Pathogenicity Analysis of Proteus mirabilis in Cynomolgus Monkey From Yunnan, China

open access: yesVeterinary Medicine and Science, Volume 12, Issue 3, May 2026.
This study demonstrated that the pathogen responsible for diarrhoea in a cynomolgus monkey was identified as Proteus mirabilis (P. mirabilis) through methods including bacterial isolation and culture, morphological examination, biochemical profiling, 16S rRNA sequencing, analysis of key virulence genes and bacterial artificial infection tests.
Heling Li   +6 more
wiley   +1 more source

ZBTB21 Is a Dual Suppressor of Pyroptosis and MHC‐I Antigen Presentation That Promotes Tumor Immune Evasion

open access: yesAdvanced Science, Volume 13, Issue 22, 17 April 2026.
ZBTB21 is a transcription factor that epigenetically suppresses pyroptosis and MHC‐I antigen presentation, enabling tumor immune evasion. Genetic ablation of ZBTB21 activates pyroptotic cell death and enhances antigen presentation, recruiting CD8+ T cells to overcome immune checkpoint blockade resistance.
Lei Zhao   +12 more
wiley   +1 more source

EVALUATION OF SINGLE-DOSE CEFOPERAZONE TREATMENT FOR GONOCOCCAL URETHRITIS [PDF]

open access: yes, 1983
男子淋菌性尿道炎患者30例に対してCefoperazone 2 g静注, 2 g筋注, 1 g筋注によるOne shot注射の治療をおこない, 著効16例, 有効13例, 無効1例で, 有効率は96.7%であった.無効例1例も本剤の追加投与にて治療した.とくに問題となる副作用はなかったThirty male patients with gonococcal urethritis were treated with a single injection of either cefoperazone 2 g
岡崎, 武二郎   +2 more
core  

Determination of Cefoperazone Based on Nano-Composite Electrode Using Coulometric FFT Admittance Voltammetry

open access: yesInternational Journal of Electrochemical Science, 2013
In this work, new nano-composite modified carbon paste electrode for Cefoperazone detection is presented. Nano-composite paste was made by mixing ionic liquid, 1-butyl-3-methylimidazolium hexafluorophosphate (BMIMPF6), grapheme nanosheets, Au and CeO2 ...
Parviz Norouzi   +3 more
doaj   +1 more source

Cefoperazone induces esterase B expression by EstR and esterase B enhances cefoperazone activity at the periplasm

open access: yesInternational Journal of Medical Microbiology, 2020
The occurrence of antibiotic resistance bacteria has become a major threat to public health. We have recently discovered a transcriptional activator that belongs to MarR family, EstR, and an esterase B (EstB) with a newly proposed de-arenethiolase ...
Neal Toewiwat   +4 more
doaj   +1 more source

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