Results 81 to 90 of about 13,451 (203)

The Evaluation of Machine Learning Models Using Matrix‐Assisted Laser Desorption/Ionization Time‐of‐Flight Mass Spectrometry (MALDI–TOF–MS) Spectra for the Prediction of Antibiotic Resistance in Klebsiella pneumoniae

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
Machine learning models developed from matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry spectra can rapidly predict antimicrobial resistance in Klebsiella pneumoniae. By transforming routine spectral data into accurate resistance profiles within minutes, this approach could reduce diagnostic delays and support earlier ...
Stephen Mark Edward Fordham
wiley   +1 more source

ANTIBACTERIAL ACTIVITY OF CEFOPERAZONE AGAINST N.GONORRHOEAE STRAINST [PDF]

, 1983
1) 1981年8月より1982年4月までに都立台東病院で臨床分離された淋菌53株に対するcefoperazoneおよびpenicillin G, ampicillin, tetracycline, kanamycin, spectinomycinの抗菌力について検討した.2) Penicillin Gおよびampicillinでは, MIC 0.8 μg/ml以上の耐性淋菌は約60%であり, MIC 25-100 μg/ml以上を示すβ-lactamase産生淋菌も5株(9%)認められた ...
岡崎, 武二郎, 三井, 一子, 鈴野, 逸雄   +2 more
core  

EVALUATION OF CEFOPERAZONE/SULBACTAM AND VITAMIN K USE IN PATIENTS WITH BACTERIAL INFECTIONS [PDF]

, 2019
Objective: The objectives of this study were to evaluate the effects of Vitamin K use for bleeding or coagulopathies prevention and to assess theoccurrence of drug-related problems in patients receiving cefoperazone/sulbactam.Methods: The prospective ...
SEESIN, THEERAPONG, BHONGCHIRAWATTANA, SIRIN, WEESAPHEN, SARAWUT, PENGSUPSIN, PITIPONG, SRIPHONG, PEERAYA, LIMPAPANASIT, UAEPONG   +5 more
core   +1 more source

Montelukast and cefoperazone act as antiquorum sensing and antibiofilm agents against Pseudomonas aeruginosa [PDF]

Aims Drug repurposing is an attractive strategy to control biofilm-related infectious diseases. In this study, two drugs (montelukast and cefoperazone) with well-established therapeutic applications were tested on Pseudomonas aeruginosa quorum sensing ...
Cerqueira, NMFSA, Simoes, M, Leitao, MM, Simões M, Anabela Borges, Vieira, TF, Sousa, SF   +6 more
core   +1 more source

Prescribing Trends of Fixed-Dose Combination Antibiotics Not Recommended by the WHO (FNRs) for ICU Patients in Six Major Areas of China During a Seven-Year Period

Drug Design, Development and Therapy
Liujun Zhou,1,* Yuhua Zhao,1,2,* Jianping Zhu,1 Jieqiong Liu,1 Gang Liang,1 Yi Yang,1 Gang Han,1 Zhenwei Yu1 1Department of Pharmacy, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, People’s Republic of China ...
Zhou L, Zhao Y, Zhu J, Liu J, Liang G, Yang Y, Han G, Yu Z   +7 more
doaj  

Tracking cefoperazone/sulbactam resistance development in vivo in A. baumannii isolated from a patient with hospital-acquired pneumonia by whole-genome sequencing

Frontiers in Microbiology, 2016
Cefoperazone/sulbactam has been shown to be efficacious for the treatment of infections caused by Acinetobacter baumannii; however, the mechanism underlying resistance to this synergistic combination is not well understood.
Xiaofen Liu, Xiaofen Liu, Huajun Zheng, Weipeng Zhang, Zhen Shen, Miao Zhao, Yuancheng Chen, Yuancheng Chen, Li Sun, Jun Shi, Jing Zhang, Jing Zhang   +11 more
doaj   +1 more source

Research on the treatment of Pseudomonas aeruginosa pneumonia in children by macrolide antibiotics

Open Medicine, 2015
To observe a therapeutic effect of macrolide antibiotics in children with Pseudomonas aeruginosa pneumonia. Fifty-four cases of children with Pseudomonas aeruginosa pneumonia were randomly divided into an observation group (n=30) and a control group (n ...
Huang Xu-qiang, Deng Li, Lu Gen, He Chun-hui, Wu Pei-qiong, Xie Zhi-wei, Aqeel Ashraf Muhammad   +6 more
doaj   +1 more source

The prevalence and antimicrobial resistance of Pseudomonas species in patients with chronic suppurative otitis media

مجله كليه طب الكندي, 2015
Background: Chronic suppurative otitis media (CSOM) is the result of an initial episode of acute otitis media and is characterized by a persistent discharge from the middle ear through a tympanic perforation for at least 2 weeks duration.
Zaid I. AL-Ataar
doaj  

METHOD DEVELOPMENT AND VALIDATION OF CEFOPERAZONE AND SULBACTAM IN DRIED BLOOD SPOTS BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY PHOTODIODE ARRAY DETECTOR [PDF]

, 2022
Objective: The primary purpose of this research was to develop a simple, precise, fast, and accurate method for measuring cefoperazone and sulbactam simultaneously in dried blood spots (DBS) using HPLC PDA.
RAMADON, DELLY, PERMATA, DIAN, HARAHAP, YAHDIANA   +2 more
core   +1 more source

Study on the time-sequential change of acetaldehyde-protein adduct and detection of metabolites of disulfiram-like reaction in rats

Egyptian Journal of Forensic Sciences
Background Disulfiram-like reactions are associated with alcohol consumption during the administration of specific drugs, and their diagnosis is a challenge in clinical and forensic medicine.
Ruijiao Lin, Zhe Zheng, Congcong Zhao, Hongbing Chen, Xin He, Minzhu Zhao, Jianbo Li   +6 more
doaj   +1 more source