Results 61 to 70 of about 17,954 (213)

The Evaluation of Machine Learning Models Using Matrix‐Assisted Laser Desorption/Ionization Time‐of‐Flight Mass Spectrometry (MALDI–TOF–MS) Spectra for the Prediction of Antibiotic Resistance in Klebsiella pneumoniae

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
Machine learning models developed from matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry spectra can rapidly predict antimicrobial resistance in Klebsiella pneumoniae. By transforming routine spectral data into accurate resistance profiles within minutes, this approach could reduce diagnostic delays and support earlier ...
Stephen Mark Edward Fordham
wiley   +1 more source

Comparison of antibiotic-associated diarrhea caused by cefoperazone/sulbactam or piperacillin/tazobactam in neurosurgery patients

Journal of International Medical Research, 2021
Objective To compare the occurrence and prognosis of antibiotic-associated diarrhea (AAD) between patients treated with cefoperazone/sulbactam and piperacillin/tazobactam in the neurosurgery department.
Yue Chen, Qiulin Xiang, Lei Liu
doaj   +1 more source

The Influence of COVID‐19 on the Composition and Drug Resistance of Pleural Effusion in Shandong Province

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
Our results show that the COVID‐19 pandemic has a significant impact on the detection of pathogens and drug resistance in pleural effusion in Shandong Province. ABSTRACT To analyze the composition and drug resistance changes of pleural effusion in Shandong region from 2017 to 2024, and to provide a basis for clinical empirical treatment and future ...
Wenwen Yu, Shuqing Ma, Fen Xu, Xiangmin Han, Ming Li, Yuanqi Zhu, Sufei Pan, Sujun Hou, Chunqing Ma, Fawen Deng, Shifu Wang, the SPARSS net Working Group, Ningning Ge, Fen Su, Renzhe Li, Fengyan Pei, Chunhua Han, Chengjie Guo, Mingju Hao, Bin Ji, Yan Sun, Xiulei Xue, Mingyan Sun, Yilei Li, Hongyun Cao, Hong He, Fang Wang, Zheng Zhou, Xiaoling Zan, Weiping Zhou, Xuejiao Leng, Chunzhong Dong, Xu Zheng, Shiying Sun, Wei Li, Yongjuan Ma, Jin Li, Xiao‐ying Li, Hongyan Bi, Jinjing Tian, Zhiyong Zhang, Ruifang Yang, Yulong Dai, Xuerong Sun, He Yi, Bo Yu, Fengzhi Bian, Qin Yi, Haiying Chen, Qingling Liu, Guixia Li, Jinfang Guo, Hongning Zhang, Huili Hou, Tao Chen, Zhiwei Liu, Ping Wu, Jiajia Feng, Li‐e Zhang, Junjie Dai, Jie Chen   +60 more
wiley   +1 more source

Cefoperazone induces esterase B expression by EstR and esterase B enhances cefoperazone activity at the periplasm

International Journal of Medical Microbiology, 2020
The occurrence of antibiotic resistance bacteria has become a major threat to public health. We have recently discovered a transcriptional activator that belongs to MarR family, EstR, and an esterase B (EstB) with a newly proposed de-arenethiolase ...
Neal Toewiwat, Wirongrong Whangsuk, Poonsakdi Ploypradith, Skorn Mongkolsuk, Suvit Loprasert   +4 more
doaj   +1 more source

Comprehensive Analysis of Structure Activity Relationships in Quinoxaline Derivatives Covering Antimicrobial Applications

ChemistrySelect, Volume 11, Issue 14, 13 April 2026.
ABSTRACT Antimicrobial resistance (AMR) has emerged as one of the most critical global health challenges, undermining the clinical efficacy of existing antibiotics and threatening modern therapeutic strategies. The ongoing misuse and overuse of antimicrobial agents have accelerated the evolution of resistant bacterial strains and parasites ...
Subham Kumar Vishwakarma, Fernando Rogério Pavan, Cesar Augusto Roque‐Borda   +2 more
wiley   +1 more source

TWO SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF CEFOPERAZONE AND CEFADROXIL IN THEIR PHARMACEUTICAL PREPARATIONS.

Zagazig Journal of Pharmaceutical Sciences, 2001
Two senstive spectrophotometric methods were adopted for determination of two cephalosporins namely cefoperazone sodium and cefadroxil. The first method was based on coupling each of the two compounds with diazotized p-nitroaniline.
Lobna Abd El Aziz
doaj   +1 more source

A study of prostatic tissue levels of cefoperazone [PDF]

, 1985
前立腺肥大症16例に対する恥骨後式前立腺被膜下摘除術時, CPZ 3 gを急速静注し, 前立腺被膜と肥大腺腫への経時的移行につき検討した.1) CPZ投与60分後両者とも移行濃度がピークとなるが, 前立腺被膜濃度は肥大腺腫濃度の約2倍に達した.2)摘出標本の組織型による比較では, 腺性優位型の方が筋性優位型と混合型よりもやや組織濃度は高かったが, 有意差ではなかった.3)前立腺組織中のCPZ濃度が高かったことから, 本剤は前立腺炎に対し有効と推定したProstatic tissue levels of ...
今村, 一男, 原口, 忠, 吉田, 英機, 小川, 良雄, 星野, 真希夫, 桜井, 秀樹, 桧垣, 昌夫, 河合, 誠朗, 石原, 八十士   +8 more
core  

Epidemiology, Management, and Alarmingly High Mortality of Burn Patients: A Retrospective Analysis From a Resource‐Limited Tertiary Centre in Syria

International Wound Journal, Volume 23, Issue 4, April 2026.
ABSTRACT Burn injuries pose a significant challenge in resource‐limited settings, particularly during humanitarian crises. This study examines the epidemiology, management, and outcomes of burn patients at a tertiary hospital in Damascus, Syria, from 2021 to 2024.
Lorieh Domat, Adel Azar, Ahmad Alkheder, Diana Mohammad, Jean Domat, Hanady Zwaraa, Rawnak Almidani   +6 more
wiley   +1 more source

Development and validation of an HPLC-DAD analytical method for quantitative and simultaneous determination of cefoperazone and prednisolone in intramammary ointment

Drug Analytical Research
Cefoperazone (CPZ) is a third-generation cephalosporin used to treat bovine mastitis. The association with steroidal anti-inflammatory drugs, such as prednisolone (PRED), provides an improvement in the animal's clinical response, which justifies its use.
Patrícia Espinosa dos Santos, Jefferson Annunciatto, Teófilo Fernando Mazon Cardoso, Marcos Serrou do Amaral, Nájla Mohamad Kassab   +4 more
doaj   +1 more source

Risk Factors for Cefoperazone/Sulbactam-Induced Coagulation Disorder

Infection and Drug Resistance, 2023
Wan Miao, Jinlin Guo, Huifang Cheng, Qianqian Zhao Department of Pharmacy, Shanxi Provincial People’s Hospital, Taiyuan, Shanxi Province, People’s Republic of ChinaCorrespondence: Jinlin Guo, Department of Pharmacy, Shanxi Provincial People’s Hospital ...
Miao W, Guo J, Cheng H, Zhao Q
doaj