Results 91 to 100 of about 67,831 (235)

Identification and Functional Characterization of Isoflavone synthase Gene Family in Pea (Pisum sativum): The Entry Point to Pisatin Biosynthesis

Legume Science, Volume 8, Issue 2, June 2026.
ABSTRACT Isoflavone synthase (IFS), a cytochrome P450 monooxygenase of the CYP93C subfamily, catalyzes the conversion of flavanones into isoflavones, the first committed step in the biosynthesis of isoflavonoid phytoalexins. In pea (Pisum sativum L.), the phytoalexin pisatin plays a pivotal role in defense against pathogens.
Muhammad Sufyan Tahir, Kuflom Kuflu, Nishat Shayala Islam, Tim McDowell, Sangeeta Dhaubhadel   +4 more
wiley   +1 more source

Dosing Regimen for Cefotaxime Should Be Adapted to the Stage of Renal Dysfunction in Critically Ill Adult Patients—A Retrospective Study

Antibiotics
Cefotaxime administration is recommended in doses of 3–12 g/day in adults with a Glomerular Filtration Rate (GFR) > 5 mL/min. This study aimed to assess the impact of renal function and obesity on cefotaxime concentrations in intensive care unit (ICU ...
Théo Dillies, Sophie Perinel-Ragey, Patricia Correia, Jérôme Morel, Guillaume Thiery, Manon Launay   +5 more
doaj   +1 more source

A comparison of antibiotic disks from different sources on Quicolor and Mueller-Hinton agar media in evaluation of antibacterial susceptibility testing [PDF]

, 2016
Background and Objectives: Antibacterial susceptibility testing of clinical bacterial isolates through disk diffusion method plays a major role in antibacterial treatment. One of the main factors affecting the result of these tests is the type, structure
Abdi-Ali, Ahya, Rezaei Hemami, Mohsen, Saffari, Neda, Salmanzadeh-Ahrabi, Siavosh   +3 more
core  

Detection of VIM-1-producing Enterobacter cloacae and Salmonella enterica Serovars Infantis and Goldcoast at a breeding pig farm in Germany in 2017 and their molecular relationship to former VIM-1-producing S. Infantis Isolates in German livestock production [PDF]

, 2019
In 2011, VIM-1-producing Salmonella enterica serovar Infantis and Escherichia coli were isolated for the first time in four German livestock farms. In 2015/2016, highly related isolates were identified in German pig production.
Borowiak, Maria, Guenther, Sebastian, Hadziabdic, Sead, Kaesbohrer, Annemarie, Malorny, Burkhard, Projahn, Michaela, Roesler, Uwe [u.v.m.], Roschanski, Nicole, Szabo, Istvan, Tenhagen, Bernd-Alois   +9 more
core   +1 more source

Gut Microbiota as a Key Modulator in the Pathophysiology of Sepsis: SURVEIL Project

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Longitudinal profiling of 132 hospitalized patients reveals that age, colonization status, and sepsis interact to shape gut microbiota diversity and composition. Sepsis is associated with reduced alpha diversity, beta‐diversity shifts, functional predictions (methanogenesis, nitrate/sulfate respiration), and partial MDR overlap with bloodstream ...
Chiara Bazzano, Alice Caramaschi, Nadia Massa, Silvio Collani, Marta Mellai, Nadia Barizzone, Andrea Rocchetti, Paolo Bottino, Maria Simona Caroppo, Valeria Bonato, Rosanna Vaschetto, Sara Scaglione, Alessia Francese, Narges Gholami, Claudio Caria, Paola Bianchi, Cristiano Lauritano, Luigi Castello, Annalisa Roveta, Antonio Maconi, Stefano Andreoni, Sandra Dalfonso, Elisa Bona   +22 more
wiley   +1 more source

When First‐Line Therapies Fail: Surgical Site Infections and the Declining Antimicrobial Utility in a Resource‐Limited Nation

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
In Belize, a 7‐year nationwide study reveals a sharp rise in antimicrobial resistance in surgical infections. ESBL‐producing bacteria more than doubled to > 45%, with critical treatment gaps and geographic hotspots identified. Sentinel pan‐drug‐resistant cases and a correlation between antibiotic use and resistance underscore the urgent need for ...
Innocent E. Nwachukwu, Cary W. Rivera, Vivian M. Reyes, Diomar Salazar, Lydia Harris‐Thurton, Danladi C. Husaini   +5 more
wiley   +1 more source

Is 24 hour observation in hospital after stopping intravenous antibiotics in neonates justified? [PDF]

, 2009
Background: Antibiotics are given empirically for suspected sepsis in up to 75% of neonates on the Neonatal and Paediatric Intensive Care Unit (NPICU), after completion of a septic screen. Treatment is discontinued on day 3 if cultures remain negative or
Andrejevic, Hermoine, Attard Montalto, Simon, Fenech, Josella, Said Conti, Valerie   +3 more
core  

Pharmacokinetic Analysis of Intravenous Push Cefepime in Critically Ill Patients With Sepsis

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 6, June 2026.
ABSTRACT Background Intravenous push (IVP) administration of cefepime increases ease of preparation and limits the need for small volume parenterals. The data on IVP pharmacokinetic/pharmacodynamic (PK/PD) parameters are limited, but may be especially relevant in critically ill patients with altered PK/PD for time‐dependent antibiotics like cefepime ...
Susan E. Smith, Rehana Bagodiya, Phuong Luong, Sakshi Shinde, Christopher M. Bland, Christopher Barry, Michael G. Bartlett, Nicholas R. Fox, Trisha N. Branan   +8 more
wiley   +1 more source

Emergence of CTX-M group 1 extended-spectrum ß-lactamase–producing Klebsiella pneumoniae strains in the community [PDF]

Medicinski Glasnik, 2010
Aim Molecular characterization of ESBL-producing K. pneumoniaestrains isolated from urine of outpatients in Zagreb regionduring the last five years. Methods During the five-year study period a total of 2, 651 K.pneumoniae strains were isolated from urine
Nataša Beader,, Maja Anušić,, Jasna Knežević,, Tamara Kukovec,, Ana Mlinarić-Džepina,, Tatjana Marijan,, Zrinka Bošnjak,, Jasmina Vraneš,, Branka Bedenić,, Petra Barl,, Vladimira Leskovar,, Smilja Kalenić,   +11 more
doaj  

Cephalosporinases associated with outer membrane vesicles released by Bacteroides spp. protect gut pathogens and commensals against beta-lactam antibiotics [PDF]

, 2014
Objectives: To identify β-lactamase genes in gut commensal Bacteroides species and to assess the impact of these enzymes, when carried by outer membrane vesicles (OMVs), in protecting enteric pathogens and commensals.
Brearley, Charles, Carding, Simon R., Cross, Kathryn, Horn, Nikki, Livermore, David M., Salt, Louise, Stentz, Régis   +6 more
core   +1 more source