Results 1 to 10 of about 15,156,055 (323)

Half-Life of Serum Elimination of Perfluorooctanesulfonate,Perfluorohexanesulfonate, and Perfluorooctanoate in Retired Fluorochemical Production Workers

Environmental Health Perspectives, 2007
Background The presence of perfluorooctanesulfonate (PFOS), perfluorohexanesulfonate (PFHS), and perfluorooctanoate (PFOA) has been reported in humans and wildlife. Pharmacokinetic differences have been observed in laboratory animals.
G. Olsen, J. Burris, D. Ehresman, John W. Froehlich, A. Seacat, J. Butenhoff, L. R. Zobel   +6 more
semanticscholar   +1 more source

Dinâmica da comunidade arbórea de uma floresta semidecidual em Uberlândia, MG, Brasil Tree community dynamics in a semideciduous forest, in Uberlândia, Minas Gerais State, Brazil

Acta Botânica Brasílica, 2009
O objetivo do trabalho foi de verificar as mudanças ocorridas na comunidade arbórea em um intervalo de 14 anos. O estudo foi realizado em uma área de floresta semidecidual utilizando 50 parcelas de 10 m×10 m, onde foram amostradas todas as árvores com ...
Mariana Resende Silva, Glein Monteiro de Araújo   +1 more
doaj   +1 more source

An Omalizumab Biobetter Antibody With Improved Stability and Efficacy for the Treatment of Allergic Diseases

Frontiers in Immunology, 2020
The critical role of IgE in allergic diseases is well-documented and clinically proven. Omalizumab, a humanized anti-IgE antibody, was the first approved antibody for the treatment of allergic diseases. Nevertheless, omalizumab still has some limitations,
Peipei Liu, Peipei Liu, Zhongzong Pan, Chunyin Gu, Xiaodan Cao, Xiaowu Liu, Jianjian Zhang, Zheng Xiao, Xueping Wang, Haibing Guo, Dianwen Ju, Su-Jun Deng   +11 more
doaj   +1 more source

Utility of Feathers for Avian Influenza Virus Detection in Commercial Poultry

Pathogens, 2023
The present study evaluated the potential utility of feather samples for the convenient and accurate detection of avian influenza virus (AIV) in commercial poultry. Feather samples were obtained from AIV-negative commercial layer facilities in Iowa, USA.
Shahan Azeem, Baoqing Guo, Yuko Sato, Phillip C. Gauger, Anna Wolc, Kyoung-Jin Yoon   +5 more
doaj   +1 more source

Strategies for extending the half-life of biotherapeutics: successes and complications

Expert Opinion on Biological Therapy
Introduction Engineering of the drug half-life in vivo has become an integral part of modern biopharmaceutical development due to the fact that many proteins/peptides with therapeutic potential are quickly cleared by kidney filtration after injection and,
U. Binder, Arne Skerra
semanticscholar   +1 more source

Modelos não lineares para a liberação de potássio de estercos animais em latossolos Non linear models to potassium release from animals manure in Latosols

Ciência Rural, 2012
Modelos não lineares são adequados para a descrição da liberação de nutrientes, uma vez que estimam quantidades de interesse prático e apresentam boa qualidade de ajuste.
Walmes Marques Zeviani, Carlos Alberto Silva, Waldete Japiassu de Oliveira Carneiro, Joel Augusto Muniz   +3 more
doaj   +1 more source

Light-based tuning of ligand half-life supports kinetic proofreading model of T cell signaling

eLife, 2019
T cells are thought to discriminate self from foreign peptides by converting small differences in ligand binding half-life into large changes in cell signaling. Such a kinetic proofreading model has been difficult to test directly, as existing methods of
D. Tischer, O. Weiner
semanticscholar   +1 more source

The αSynuclein half-life conundrum

Neurobiology of Disease
αSynuclein (αSyn) misfolding and aggregation frequently precedes neuronal loss associated with Parkinson's Disease (PD) and other Synucleinopathies. The progressive buildup of pathological αSyn species results from alterations on αSyn gene and protein ...
Anna Masato, Luigi Bubacco
doaj   +1 more source

Half-Life of African Swine Fever Virus in Shipped Feed

Emerging Infectious Diseases, 2019
African swine fever virus is transmissible through animal consumption of contaminated feed. To determine virus survival during transoceanic shipping, we calculated the half-life of the virus in 9 feed ingredients exposed to 30-day shipment conditions ...
A. Stoian, J. Zimmerman, J. Ji, T. Hefley, S. Dee, D. Diel, R. Rowland, M. Niederwerder   +7 more
semanticscholar   +1 more source

Free and Immobilized Microbial Culture–Mediated Crude Oil Degradation and Microbial Diversity Changes Through Taxonomic and Functional Markers in a Sandy Loam Soil

Frontiers in Environmental Science, 2022
Crude oil contamination of soil and water resources is a widespread issue. The present study evaluated the degradation of aliphatic hydrocarbons (C11–C36) in crude oil by 17 bacteria isolated from a crude oil–contaminated soil. The results suggested that
Ashish Khandelwal, Ashish Khandelwal, Ramya Sugavanam, B. Ramakrishnan, Anirban Dutta, Eldho Varghese, Lata Nain, Tirthankar Banerjee, Neera Singh   +8 more
doaj   +1 more source