Population pharmacokinetic model of cefazolin in total hip arthroplasty
Scientific Reports, 2021 Cefazolin is an antibiotic recommended for infection prevention in total hip arthroplasty (THA). However, the dosing regimen necessary to achieve therapeutic concentrations in obese patients remains unclear.
J. Lanoiselée +9 more
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Arthroplasty Today, 2022 Background: Periprosthetic joint infection (PJI) remains one of the most devastating complications following total joint arthroplasty. Appropriate prophylactic antimicrobial administration and antibiotic stewardship are major factors impacting the risk ...
Dionisio Ortiz, III, MD +4 more
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Antibiotics, 2022 Surgical site infections are among the most prevalent and costly healthcare-associated infections, resulting in poor patient outcomes and even death. Cefazolin is a first-generation cephalosporin antibiotic that is widely used for surgical prophylaxis in
Nehad J. Ahmed +5 more
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Cefazolin Versus Flucloxacillin for Methicillin-Susceptible Staphylococcus aureus Bone and Joint Infections: A Retrospective Single-Center Comparative Study of Effectiveness and Renal Safety of Intravenous Monotherapy [PDF]
AntibioticsBackground/Objectives: In methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia, randomized evidence indicates comparable efficacy of cefazolin and antistaphylococcal penicillins with less nephrotoxicity; whether this extends to bone and joint ...
Felix Werneburg +5 more
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Cefazolin inoculum effect among methicillinsusceptible Staphylococcus aureus isolated from patients with skin infections [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2021 Objective. To evaluate frequency and intensity of cefazolin inoculum effect among methicillin-susceptible staphylococci isolated from patients with skin infections. Materials and Methods.
Vaganova А.N. +7 more
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Removal of the Cefazolin Antibiotic Using Polyaniline Resin-Polyethylene Glycol from Aqueous Medium [PDF]
آب و فاضلاب, 2022 Cefazolin is a widely used antibiotic in the treatment of bacterial infections that enters the water sources in original or metabolized form through the discharge of sewage and effluents.
Mozhgan Arman +3 more
doaj +1 more source
Clinical pharmacology of cefazolin
Advances in Biomedical and Health Sciences, 2022 Cefazolin is a first-generation cephalosporin that is active against gram-positive bacteria and has modest activity against gram-negative organisms, and cefazolin is excreted by glomerular filtration.
Gian Maria Pacifici
doaj +1 more source
Microbiology Spectrum, 2022 Cefazolin, an active in vitro agent against Escherichia coli, is used to treat urinary and biliary tract infections. Cefazolin is used widely as an antibiotic, and the increase in the emergence of cefazolin-resistant E.
Masato Kawamura +7 more
doaj +1 more source
Durability of the two-lumen catheter in hemodialysis patients; Ethanol 70%-heparin versus cefazolin-heparin: a randomized, double-blind clinical trial study [PDF]
Journal of Nephropharmacology, 2023 Introduction: Maintenance of hemodialysis catheters is essential for the patients and medical staff due to their repeated use for hemodialysis and other therapeutic interventions in the hospital.
Hadi Yousefi +7 more
doaj +1 more source
Trial of Vancomycin and Cefazolin as Surgical Prophylaxis in Arthroplasty.
New England Journal of Medicine, 2023 BACKGROUND The addition of vancomycin to beta-lactam prophylaxis in arthroplasty may reduce surgical-site infections; however, the efficacy and safety are unclear.
T. Peel +18 more
semanticscholar +1 more source