Results 61 to 70 of about 1,567 (130)

Comparing probability of target attainment against Staphylococcus aureus for ceftaroline fosamil, vancomycin, daptomycin, linezolid, and ceftriaxone in complicated skin and soft tissue infection using pharmacokinetic/pharmacodynamic models

, 2021
For recently licensed antibiotics, such as the cephalosporin ceftaroline fosamil, probability of target attainment (PTA) curves, showing the percentage of patients reaching a predefined pharmacokinetic (PK)/pharmacodynamic (PD) target at different ...
Macpherson, M, Iaconis, J, Cristinacce, A, Das, S, Wright, JG   +4 more
core   +1 more source

New Antibiotics for the Treatment of Acute Bacterial Skin and Soft Tissue Infections in Pediatrics

Pharmaceuticals, 2020
Acute bacterial skin and soft tissue infections (aSSTIs) are a large group of diseases that can involve exclusively the skin or also the underlying subcutaneous tissues, fascia, or muscles.
Nicola Principi, Alberto Argentiero, Cosimo Neglia, Andrea Gramegna, Susanna Esposito   +4 more
doaj   +1 more source

A systematic review with meta-analysis and indirect comparison of the results of studies evaluating the efficacy and safety of ceftobiprole and ceftaroline in adult patients in the treatment of infections of various localizations

Реальная клиническая практика: данные и доказательства
Objective. To compare the efficacy and safety of fifth-generation cephalosporins (ceftaroline fosamil and ceftobiprole) when used in adult in the treatment of infections of various localization.   Materials and methods.
Yu. M. Gomon, A. S. Petrichenko
doaj   +1 more source

Ceftaroline activity on certain respiratory tract and wound infection agents at the minimum inhibitory concentration level

Journal of Infection in Developing Countries, 2015
Introduction: The aim of this study was to investigate the effectiveness of ceftaroline against agents frequently isolated from respiratory tract and wound infections. Methodology: The study included a total of 250 strains isolated from various clinical
Keramettin Yanik, Emin Guluzade, Kemal Bilgin, Adil Karadag, Cafer Eroglu, Asuman Birinci, Murat Gunaydin   +6 more
doaj   +1 more source

Ceftaroline fosamil salvage therapy : an option for reduced-vancomycin-susceptible MRSA bacteraemia

, 2015
Objectives To examine the activity of ceftaroline against reduced-vancomycin-susceptible MRSA isolates. Methods One-hundred and three MRSA blood culture isolates (predominantly ST239-MRSA-III), with varying vancomycin phenotypes, had their ceftaroline ...
Jensen, Slade O. (R16034), Espedido, Bjorn (R16206), Hal, Sebastiaan J. van (R17037)   +2 more
core   +1 more source

Antimicrobial therapy of community-acquired pneumonia in a hospital setting (clinical and economic aspects)

Фармакоэкономика, 2018
The aim is to study the clinical and economic components of antimicrobial therapy (AMT) of community-acquired pneumonia (CAP) in a hospital ptactice.Materials and methods.
O. V. Zhukova, O. V. Ruina, M. V. Khazov, S. V. Romanov   +3 more
doaj   +1 more source

A Randomized, Prospective Study of Pediatric Patients With Community-acquired Pneumonia Treated With Ceftaroline Versus Ceftriaxone

, 2018
Background: Community-acquired bacterial pneumonia (CABP) remains a major infection among children, despite the use of pneumococcal vaccination. Ceftaroline fosamil is a broad-spectrum cephalosporin antibiotic with activity against many bacteria ...
Cannavino CR, Bradley JS, Friedland HD, Kaplan SL, O'Neal T, Németh Ágnes, Jandourek A, Korczowski B   +7 more
core   +1 more source

Ceftaroline Fosamil: A Novel Broad-Spectrum Cephalosporin with Activity Against Methicillin-Resistant Staphylococcus aureus

, 2011
Objective: To review the pharmacology, microbiology, chemistry, in vitro activity, pharmacokinetics, clinical efficacy, safety, dosage, and administration of ceftaroline fosamil (Teflaro, Forest Laboratories, Inc.), a novel parenteral broad-spectrum ...
Daryl D DePestel, Margaret R Jorgenson, Peggy L Carver   +2 more
core   +1 more source

Community-acquired pneumonia in hospitalized patients: clinical guidelines

Медицинский совет, 2019
Community-acquired pneumonia is still the cornerstone of practical public health care due to high morbidity and mortality. Streptococcus pneumoniae (30-50%), Haemophilus influenzae, Staphylococcus aureus and Klebsiella pneumoniae remain the main cause of
A. A. Zaytsev, A. I. Sinopal’nikov
doaj   +1 more source

Enhanced Antibiotic Removal Using Fe-Doped ZnS Nanoparticles

Micro
The environmental persistence of β-lactam antibiotics represents a growing ecological concern, requiring materials capable of combined adsorption and catalytic degradation. Herein, pure ZnS and 1% Fe-doped ZnS nanoparticles were synthesized via microwave-
Sonia J. Bailón-Ruiz, Yarilyn Cedeño-Mattei, Nayeli Colón-Dávila, Luis Alamo-Nole   +3 more
doaj   +1 more source