Results 161 to 170 of about 13,550 (188)

Predictors of Resistance to Ceftazidime-Avibactam in Carbapenem-Resistant Enterobacterales

Infectious Diseases in Clinical Practice, 2022
Background Ceftazidime-avibactam (CAZ-AVI) is a safe and effective treatment option for carbapenem-resistant Enterobacterales (CRE). However, predictors of resistance to CAZ-AVI have not been well defined. Therefore, our study describes risk factors for resistance to CAZ-AVI in hospitalized patients with CRE infections.
Tae Eun Park, Eris Cani, Paul Kelly, Lendelle Raymond, Banibrata Roy, Cosmina Zeana, Anupama Menon   +6 more
openaire   +1 more source

In Vitro Comparison of Aztreonam/Amoxicillin-Clavulanate Versus Aztreonam/Ceftazidime-Avibactam on Ceftazidime-Avibactam Resistant Stenotrophomonas maltophilia

Microbial Drug Resistance, 2022
We investigated the in vitro susceptibility of ceftazidime-avibactam (CZA) resistant Stenotrophomonas maltophilia to the associations aztreonam/amoxicillin-clavulanate (ATM-AMC) and ATM-CZA. Forty clinical isolates of S. maltophilia
Lise Crémet, Léo Joffraud, Emmanuel Eschapasse, Tiphaine Bihouée, Adrien Tissot, Sophie Gibaud, Elise Persyn   +6 more
openaire   +3 more sources

The activity of ceftazidime/avibactam against carbapenem-resistant Pseudomonas aeruginosa

Infectious Diseases, 2021
To the Editor, In this journal attempts to circumvent carbapenem resistance of Pseudomonas aeruginosa were recently reported [1]. Among 28 clinical carbapenem-resistant isolates of P.
Carmen Antonia Sanches, Ito, Larissa, Bail, Lavinia Nery Villa Stangler, Arend, Keite da Silva, Nogueira, Felipe Francisco, Tuon   +4 more
openaire   +2 more sources

Klebsiella pneumoniae Carbapenemase Variants Resistant to Ceftazidime-Avibactam: an Evolutionary Overview

Antimicrobial Agents and Chemotherapy, 2022
First variants of the Klebsiella pneumoniae carbapenemase (KPC), KPC-2 and KPC-3, have encountered a worldwide success, particularly in K. pneumoniae isolates. These beta-lactamases conferred resistance to most beta-lactams including carbapenems but remained susceptible to new beta-lactam ...
Hobson, Claire Amaris, Pierrat, Gautier, Tenaillon, Olivier, Bonacorsi, Stéphane, Bercot, Béatrice, Jaouen, Ella, Jacquier, Hervé, Birgy, André   +7 more
openaire   +4 more sources

Identifying Spectra of Activity and Therapeutic Niches for Ceftazidime-Avibactam and Imipenem-Relebactam against Carbapenem-Resistant Enterobacteriaceae

Antimicrobial Agents and Chemotherapy, 2017
We determined imipenem, imipenem-relebactam, ceftazidime, and ceftazidime-avibactam MICs against 100 CRE isolates that underwent whole-genome sequencing.
Ghady Haidar, Cornelius J Clancy, Liang Chen   +2 more
exaly   +2 more sources

Ceftazidime – Avibactam susceptibility among carbapenem-resistant Enterobacterales in a pilot study in Turkey

Acta Microbiologica et Immunologica Hungarica, 2021
AbstractThis study aimed to detect carbapenemase genes and to determine the in vitro susceptibility of Ceftazidime-Avibactam (CZA) in Enterobacterales isolates. Carbapenemase genes were detected by polymerase chain reaction. CZA sensitivity of isolates was evaluated with broth microdilution (BMD) and disk diffusion methods.
Hasan Selcuk Ozger, Ebru Evren, Serap Suzuk Yildiz, Cigdem Erol, Fatma Bayrakdar, Ozlem Azap, Alpay Azap, Esin Senol   +7 more
openaire   +4 more sources

In-house rapid colorimetric method for detection of ceftazidime/avibactam resistance in carbapenem resistant Enterobacterales

Journal of Chemotherapy, 2020
A rapid colorimetric method, the Andrade screening antimicrobial test, was compared with the E-test method to detect ceftazidime/avibactam (CZA) resistance in carbapenem resistant Enterobacterales clinical isolates. A 106 non-duplicated isolates (86 susceptible and 20 resistant to CZA) were chosen for validation.
Carla Villarroel, Lora, Marcela, Nastro, Carlos, Vay, Angela, Famiglietti, Carlos Hernán, Rodríguez   +4 more
openaire   +2 more sources

[Single - molecule, real - time sequencing of ceftazidime - avibactam - resistant Pseudomonas aeruginosa and the mechanism of resistance to ceftazidime - avibactam].

Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control
To perform single-molecule, real-time sequencing of ceftazidime-avibactam (CAZ-AVI)-resistant Pseudomonas aeruginosa and to investigate the mechanism underlying ceftazidime-avibactam resistance in P. aeruginosa.The susceptibility of 89 P. aeruginosa isolates randomly sampled from clinical specimens in Sanming First Hospital Affiliated to Fujian Medical
L, Wan, W, Liu, Y, Zhou, H, Weng, X, Cai, C, Mao   +5 more
openaire   +1 more source

Emergence of ceftazidime-avibactam resistance in clinical Klebsiella pneumoniae during therapy

European Journal of Clinical Microbiology & Infectious Diseases
The emergence of ceftazidime-avibactam resistance in Klebsiella pneumoniae poses a significant public health threat, driven by mutations in the bla . This study investigates the evolution of KPC variants (KPC-33, KPC-84, KPC-190) during therapy, highlighting their impact on resistance profiles and treatment challenges. Understanding these mechanisms is
Siquan, Shen, Xiren, Deng, Lu, Guo, Li, Yang, Hua, Yu, Fupin, Hu, Xiangning, Huang   +6 more
openaire   +2 more sources

Carbapenem-resistant Klebsiella pneumoniae meningitis and abscess treated with ceftazidime-avibactam

Enfermedades infecciosas y microbiologia clinica (English ed.), 2022
Mehmet Yasir, Pektezel, Ilkay, Isikay, Rahsan, Gocmen, Ahmet Cagkan, Inkaya   +3 more
openaire   +2 more sources