Results 171 to 180 of about 118,016 (256)

Evaluation of Drug–Drug Interaction Potential Between the Oral Antibiotic Zoliflodacin and the CYP3A4 Inhibitor Itraconazole: A Phase 1 Study in Healthy Participants

Clinical and Translational Science, Volume 19, Issue 3, March 2026.
ABSTRACT Zoliflodacin is a first‐in‐class oral spiropyrimidinetrione antibiotic being developed for patients with uncomplicated gonorrhea, including those infected with multidrug‐resistant strains. Because zoliflodacin is metabolized by cytochrome P450 3A4 (CYP3A4), concomitant administration with a CYP3A inhibitor has the potential to increase ...
Alison Luckey, Kajal B. Larson, Noha Rayad, Markus Heep, Sophie Delhomme, Gabrielle Kornmann, John P. Mueller, John P. O'Donnell, Seamus O'Brien, Rainard Fuhr, Jean‐Yves Gillon   +10 more
wiley   +1 more source

Efficacies of Single-Dose Ceftriaxone Regimens in Treating Gonococcal Paraurethral Duct Infection in Men. [PDF]

Am J Mens Health
Fan W, Zhang Q, Wei M, Zhu Y.
europepmc   +1 more source

Gonorrhea Management in High‐, Limited‐ and No‐Resource Settings: Implications in the Context of Antimicrobial Resistance

International Journal of Dermatology, Volume 65, Issue 3, Page 444-455, March 2026.
ABSTRACT Gonorrhea, a common sexually transmitted infection caused by Neisseria gonorrhoeae, represents an escalating global public health threat due to antimicrobial resistance. The current review explores diverse approaches around the globe to gonorrhea management across various settings, with a focus on diagnostic strategies, treatment practices ...
Andrei Tanasov, Maciej Pastuszczak, George‐Sorin Tiplica   +2 more
wiley   +1 more source

Antimicrobial Resistance and Infant Mortality in Sri Lanka: A Retrospective Cohort Study

Journal of Paediatrics and Child Health, Volume 62, Issue 3, Page 446-455, March 2026.
ABSTRACT Objective Sepsis is a major cause of mortality among children, with the highest burden evident in neonates and young infants, particularly, in resource‐constrained healthcare settings. Despite this burden, there are insufficient published data to delineate the epidemiology of neonatal sepsis from many of these settings.
Gayana P. S. Gunaratna, Michelle L. Harrison, Benjamin F. R. Dickson, Rajeev Sathanandaraja, T. M. Ruwanthi Perera, Nambage Shirani Chandrasiri, Anasuya Sutharson, Jannah Baker, Phoebe C. M. Williams   +8 more
wiley   +1 more source

Fatal Renal Mucormycosis Following Pediatric Deceased Donor Kidney Transplantation in a High‐Risk Recipient: A Case Report

Pediatric Transplantation, Volume 30, Issue 3, March 2026.
ABSTRACT Background Mucormycosis is a rare but devastating opportunistic fungal infection in immunocompromised hosts with particularly high morbidity and mortality in solid organ transplant recipients. Pediatric cases are exceedingly rare, and outcomes are often fatal.
Cecil Steven Levy, Trusha Nana, Yvonne Perner, Zafar Ahmed Khan, Gabriel Lindokuhle Mahlase, Nokukhanya Ngubane‐Mwandla, Gary Peiser, Sonya Kolman, Karen Petersen   +8 more
wiley   +1 more source

Real-world evaluation of ceftriaxone-related safety events: a stewardship call to action. [PDF]

Antimicrob Steward Healthc Epidemiol
Paciullo K, Suchindran S, Hojat LS, Albrecht B, Green SB, Jones KA, Rogers DJ, Vu TP, Witt LS.   +8 more
europepmc   +1 more source

Antimicrobial Resistance in Salmonella Across Aquaculture, Seafood and Related Aquatic Environments: A Scoping Review With Exploratory Textual Analysis

Reviews in Aquaculture, Volume 18, Issue 2, March 2026.
This scoping review with textual analysis maps antimicrobial resistance in Salmonella across aquaculture, seafood, and related aquatic environments. Across 93 studies, recurrent MDR patterns suggest sentinel serotypes (S. Typhimurium, S. Newport) and a minimal antimicrobial susceptibility testing (AST) panel to guide matrix‐stratified One Health ...
Cristiane Coimbra de Paula, Yuri Duarte Porto, Vinícius Silva Castro, Érica do Carmo Dias Matos, Adelino Cunha‐Neto, Ricardo César Tavares Carvalho, Luciana Kimie Savay‐da‐Silva, Eduardo Eustáquio de Souza Figueiredo, Tathiana Ferguson Motheo   +8 more
wiley   +1 more source

Correction to "Neuroprotective Effect of Ceftriaxone on MPTP-Induced Parkinson's Disease Mouse Model by Regulating Inflammation and Intestinal Microbiota". [PDF]

Oxid Med Cell Longev
europepmc   +1 more source

Trends in population structure, antimicrobial susceptibility and resistance determinants of <i>Neisseria gonorrhoeae</i> isolates from surveillance in the Kanto region, Japan, 2017-2023. [PDF]

JAC Antimicrob Resist
Kanesaka I, Komori K, Morita M, Aoki K, Manoharan-Basil SS, Kenyon C, Kanayama Katsuse A, Tateda K, Kobayashi I, Ishii Y.   +9 more
europepmc   +1 more source

App-Based Training Module on Guiding Physicians' Prescription for Antibiotic Treatment of Gonorrhea: Cluster Randomized Controlled Trial.

JMIR Mhealth Uhealth
Jiang TT, Zhang XB, Zhao PZ, Fei LJ, Chen HM, Yang YQ, Jia MH, Wang C, Shen YL, Xu YJ, Han Y, Yin YP, Chen XS.   +12 more
europepmc   +1 more source