Results 61 to 70 of about 89,539 (238)

Ceftriaxone‐induced liver injury: Incidence, phenotypic characterization and predictive factors

British Journal of Clinical Pharmacology, EarlyView.
Introduction Ceftriaxone is a widely used third‐generation cephalosporin in hospitalized patients. Although generally considered safe, it has been associated with hepatobiliary complications and emerging reports of drug‐induced liver injury (DILI). However, data on its true incidence, phenotypic patterns, and predictors remain limited. This study aimed
Mohamed Hatem, Mohannad N. AbuHaweeleh, Humam Emad Rajha, Mhd Osama Rahhal, Ahmad Hamdan, Lina Naseralallah   +5 more
wiley   +1 more source

Endocardite infecciosa por Haemophilus aphrophilus: relato de caso Infective endocarditis due to Haemophilus aphrophilus: a case report

Jornal de Pediatria, 2008
OBJETIVO: Descrever o caso de uma criança com endocardite infecciosa causada por Haemophilus aphrophilus. DESCRIÇÃO: Menino com febre e calafrios há 20 dias.
Ricardo M. Pereira, Fabio Bucaretchi, Antonia T. Tresoldi   +2 more
doaj   +1 more source

Clinical Model‐Informed Precision Dosing Consult Service for Accelerating Personalized Medication in Pediatric Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor, Takanobu Nadai, Kei Irie, Wen Rui Tan, Sanjana Parikh, Anhar Hosawi, Matthijs W. van Hoogdalem, Ronaldo Morales Junior, Sonya Tang Girdwood, Abbie D. Leino, Kana Mizuno, Alexander A. Vinks, Tomoyuki Mizuno   +12 more
wiley   +1 more source

Cephalosporins’ Cross-Reactivity and the High Degree of Required Knowledge. Case Report and Review of the Literature

Antibiotics, 2020
Antibiotic cross-reactivity represents a phenomenon of considerable interest as well as antibiotic resistance. Immediate reactions to cephalosporins are reported in the literature with a prevalence of only 1–3% of the population, while anaphylactic ...
Stefano D’Errico, Paola Frati, Martina Zanon, Eleonora Valentinuz, Federico Manetti, Matteo Scopetti, Alessandro Santurro, Vittorio Fineschi   +7 more
doaj   +1 more source

Genomic Insights Into Spatiotemporal Dynamics of Acquired Azithromycin Resistance Genes in Salmonella Strains Worldwide

Food Safety and Health, EarlyView.
ABSTRACT Azithromycin has been used for clinical invasive infections caused by fluoroquinolone‐ and third‐generation cephalosporin‐resistant Salmonella, and mass drug administration with azithromycin has been used to reduce under‐5 mortality in children in some countries.
Yuhang Pei, Mengqi Qu, Ziru Yang, Xuebin Xu, Yanan Wang   +4 more
wiley   +1 more source

Adverse reaction to ceftriaxone in a 28-day-old infant undergoing urgent craniotomy due to epidural hematoma: review of neonatal biliary pseudolithiasis [PDF]

, 2015
Alicja Bartkowska-Śniatkowska,1 Katarzyna Jończyk-Potoczna,2 Marzena Zielińska,3 Jowita Rosada-Kurasińska1 1Department of Pediatric Anesthesiology and Intensive Therapy, Poznan University of Medical Sciences, Poznan, Poland; 2Department of Pediatric ...
Rosada-Kurasińska J, Jończyk-Potoczna K, Bartkowska-Śniatkowska A, Zielińska M   +3 more
core   +1 more source

Pharmacodynamic evaluation of ceftriaxone single-dose therapy (0.125-1 g) to eradicate ceftriaxone-susceptible and ceftriaxone-resistant Neisseria gonorrhoeae strains in a hollow fibre infection model for gonorrhoea [PDF]

BACKGROUND: Antimicrobial resistance in Neisseria gonorrhoeae is threatening the gonorrhoea treatment, and optimizations of the current ceftriaxone-treatment regimens are crucial.
Golparian, Daniel,, Drusano, George,, Oxelbark, Joakim,, Louie, Arnold,, Jacobsson, Susanne,, Kong, Fabian Y S,, Brown, David,, Unemo, Magnus,   +7 more
core   +1 more source

Incidence of gallbladder lithiasis after ceftriaxone treatment [PDF]

, 1990
Ceftriaxone has potent activity against a broad range of Gram-positive and Gram-negative bacteria. While it is eliminated mainly by the kidney, 10-20% of the drug is eliminated in the bile and ceftriaxone salt precipitates have been described in the ...
A. Anderegg, J. J. Gonvers, A. Cometta, L. Cantoni, Cometta, A., M. P. Glauser, Gallot-Lavallée-Villars, S., Anderegg, A., Glauser, M.P., Iten, A., S. Gallot-Lavallée-Villars, Gonvers, J.J., A. Iten, Cantoni, L.   +13 more
core   +1 more source

Ceftriaxone Prescription at Muhimbili National Hospital [PDF]

, 2020
S Background: Since their discovery, antibiotics have contributed to a dramatic fall in morbidity and mortality from bacterial infections. However, the emergence and spread of antibiotic resistance continues to threaten the effectiveness of these agents.
Sasi, Philip Galula
core   +1 more source

Molecular Typing of Neisseria gonorrhoeae Clinical Isolates in Russia, 2018–2019: A Link Between penA Alleles and NG-MAST Types

Pathogens, 2020
This work aimed to study penA gene polymorphisms in clinical isolates of Neisseria gonorrhoeae collected in Russia in 2018–2019 and the contribution of the penA allele type to susceptibility to β-lactam antibiotics. A total of 182 isolates were analyzed.
Ilya Kandinov, Ekaterina Dementieva, Dmitry Kravtsov, Alexander Chestkov, Alexey Kubanov, Victoria Solomka, Dmitry Deryabin, Dmitry Gryadunov, Boris Shaskolskiy   +8 more
doaj   +1 more source