Results 141 to 150 of about 66,137 (309)

Celecoxib approved as NSAID with some concessions on class warning [PDF]

, 1999
Jane L. Miller
openalex   +1 more source

COX inhibition: Catalepsy and Striatum Dopaminergic-GABAergic-Glutamatergic Neurotransmission [PDF]

, 2008
Selective COX-2 and COX-1 inhibitors were administered (i.p. acutely) to normal and parkinsonian rats, followed by the analysis of the striatal dopamine, GABA and glutamate concentrations using the microdialysis technique, simultaneously, the catalepsy ...
Abbas Shafiee, Amin Gravand, Davood Barzegar-Pourshuraki, Hadi Fathi-Moghaddam, Hojat Ebrahiminik, Latifeh Navidpour, Mehdi Shafiee Ardestani, Meysam Shafiee Ardestani   +7 more
core   +1 more source

Chemoprevention of Gastrointestinal Cancers: An Umbrella Review of Meta‐Analyses of Randomized Controlled Trials and Cohort Studies

Clinical and Translational Science, Volume 18, Issue 5, May 2025.
ABSTRACT Several meta‐analyses have investigated the association between chemopreventive agents (CPAs) and the risk of gastrointestinal cancers, but syntheses of the quality of evidence in aggregate are lacking. This umbrella review aimed to assess the quality of evidence from meta‐analyses of randomized controlled trials (RCTs) and cohort studies that
Jia En Chan, Suresh Shanmugham, Suresh Kumar, Yeong Yeh Lee, Siew Mooi Ching, Nathorn Chaiyakunapruk, Sajesh K. Veettil   +6 more
wiley   +1 more source

Randomized trial of switching from prescribed non-selective non-steroidal anti-inflammatory drugs to prescribed celecoxib: the Standard care vs. Celecoxib Outcome Trial (SCOT)

European Heart Journal, 2016
Background Selective cyclooxygenase-2 inhibitors and conventional non-selective non-steroidal anti-inflammatory drugs (nsNSAIDs) have been associated with adverse cardiovascular (CV) effects.
T. MacDonald, C. Hawkey, I. Ford, J. McMurray, J. Scheiman, J. Hallas, E. Findlay, D. Grobbee, F. Hobbs, S. Ralston, D. Reid, M. Walters, J. Webster, F. Ruschitzka, L. Ritchie, S. Perez-Gutthann, E. Connolly, N. Greenlaw, Adam Wilson, Li Wei, I. Mackenzie   +20 more
semanticscholar   +1 more source

Inhibitory effect of celecoxib on agomelatine metabolism in vitro and in vivo

Drug Design, Development and Therapy, 2018
Jiayang He,1 Ping Fang,2 Xiang Zheng,2 Chenchen Wang,2 Tenghui Liu,2 Bowen Zhang,2 Jian Wen,2 Ren-ai Xu3 1Department of Pharmacy, The First Hospital of Jiaxing, Jiaxing, Zhejiang, China; 2Department of Pharmacology, School of Pharmacy of Wenzhou Medical
He JY, Fang P, Zheng X, Wang CC, Liu TH, Zhang BW, Wen J, Xu RA   +7 more
doaj  

New Onset of Primary Membranous Nephropathy After COVID‐19 mRNA Vaccination in Affected Sjögren's Syndrome

Nephrology, Volume 30, Issue 5, May 2025.
ABSTRACT The global administration of mRNA vaccines in response to the coronavirus disease 2019 (COVID‐19) pandemic has been crucial in mitigating the spread of the virus. While these vaccines are generally safe and effective, there have been occasional reports of rare adverse effects, including new‐onset nephropathies. Primary Sjögren's syndrome (pSS),
Chia‐Wei Tseng, Jing‐Huan Liao, Tai‐Kuang Chao, Shun‐Neng Hsu   +3 more
wiley   +1 more source

Celecoxib was similar to naproxen for rheumatoid arthritis with fewer endoscopic ulcers [PDF]

, 2000
David Henry
openalex   +3 more sources

Mol-AIR: Molecular Reinforcement Learning with Adaptive Intrinsic Rewards for Goal-directed Molecular Generation [PDF]

arXiv
Optimizing techniques for discovering molecular structures with desired properties is crucial in artificial intelligence(AI)-based drug discovery. Combining deep generative models with reinforcement learning has emerged as an effective strategy for generating molecules with specific properties.
arxiv  

The Cost-effectiveness of Celecoxib versus Non-steroidal Anti-inflammatory Drugs plus Proton-pump Inhibitors for Treating Osteoarthritis in Algeria

Journal of Health Economics and Outcomes Research, 2013
**Background:** Cyclooxygenase-2 inhibitors such as celecoxib are as effective as non-selective non-steroidal anti-inflammatory drugs (ns-NSAIDs) in the treatment of osteoarthritis (OA), have fewer gastrointestinal side effects, but are more expensive. *
Nadir Hammoumraoui, Sid Ahmed Kherraf, Joaquin Mould-Quevedo, Tarek A. Ismail   +3 more
doaj  

Cardiorenal Effects of Newer NSAIDs (Celecoxib) versus Classic NSAIDs (Ibuprofen) in Patients with Arthritis

Journal of Toxicology, 2011
Background. Arthritis is a common condition that co-exists in the elderly population. This condition leads to frequent administration of comorbid analgesics especially non steroidal anti-inflammatory drugs (NSAIDs). Aim.
Ragia Hegazy, Mohamed Alashhab, Madiha Amin   +2 more
doaj   +1 more source