Results 151 to 160 of about 66,137 (309)

Antitumor activity of the selective cyclooxygenase-2 inhibitor, celecoxib, on breast cancer in Vitro and in Vivo

Cancer Cell International, 2012
Background Cyclooxygenase-2(COX-2) promotes carcinogenesis, tumor proliferation, angiogenesis, prevention of apoptosis, and immunosuppression. Meanwhile, COX-2 over-expression has been associated with tumor behavior and prognosis in several cancers. This
Dai Zhi-Jun, Ma Xiao-Bin, Kang Hua-Feng, Gao Jie, Min Wei-Li, Guan Hai-Tao, Diao Yan, Lu Wang-Feng, Wang Xi-Jing   +8 more
doaj   +1 more source

Freispruch für Celecoxib [PDF]

MMW - Fortschritte der Medizin, 2016
Mehr als zehn Jahre nach dem sog. Vioxx®-Skandal spricht eine grose prospektive randomisierte Studie den COX-2-Inhibitor Celecoxib vom Verdacht auf kardiovaskulare Schadwirkungen frei. Doch die Studie weist Limitationen auf.
openaire   +2 more sources

Impact of a selective cyclooxygenase-2 inhibitor, celecoxib, on cortical excitability and electrophysiological properties of the brain in healthy volunteers: A randomized, double-blind, placebo-controlled study.

PLoS ONE, 2019
The inflammatory response is considered a defence mechanism against physical or infectious insults and is prevalent within the central nervous system.
Jung-Ah Lim, Ki-Young Jung, Boram Park, Tae-Joon Kim, Jin-Sun Jun, Keun Tae Kim, Tae-Won Yang, Soon-Tae Lee, Keun-Hwa Jung, Kon Chu, Sang Kun Lee, Kyung-Il Park   +11 more
doaj   +1 more source

Evaluation of health-related quality of life of rheumatoid arthritis patients treated with celecoxib [PDF]

, 2000
Sean Z. Zhao, Justus I. Fiechtner, Elizabeth A. Tindall, Seema D. Dedhiya, William W. Zhao, Jane T. Osterhaus, Shawn Yu   +6 more
openalex   +1 more source

The use of topical diclofenac in the pain management of osteoarthritis of the knee [PDF]

, 2006
Osteoarthritis (OA) is a common complaint that affects millions of people worldwide. As there is no cure for OA, drug treatment is the main form of management.
Banning, M
core  

Calcium Alginate and Calcium Alginate-Chitosan Beads Containing Celecoxib Solubilized in a Self-Emulsifying Phase

Scientifica, 2016
In this work alginate and alginate-chitosan beads containing celecoxib solubilized into a self-emulsifying phase were developed in order to obtain a drug delivery system for oral administration, able to delay the drug release in acidic environment and to
L. Segale, L. Giovannelli, Paolo Mannina, F. Pattarino   +3 more
semanticscholar   +1 more source

The celecoxib long-term safety study (CLASS): celecoxib is associated with less renal toxicity compared to conventional NSAIDs [PDF]

, 2000
A. Whalton
openalex   +1 more source

GI toxicity of celecoxib vs traditional NSAIDs [PDF]

, 2000
Richard Brasington
openalex   +1 more source

Room 301, 10/18/2000 2: 00 PM - 3: 30 PM (PD) Postoperative Analgesic Effects of Celecoxib or Rofecoxib after Spinal Fusion Surgery [PDF]

, 2000
Scott S. Reuben, Neil Roy Connelly
openalex   +1 more source

Induction but not inhibition of COX-2 confers human lung cancer cell apoptosis by celecoxib

Journal of Lipid Research, 2013
The antitumorigenic mechanism of the selective cyclooxygenase-2 (COX-2) inhibitor celecoxib is still a matter of debate. Among different structurally related COX-2 inhibitors, only celecoxib was found to cause apoptosis and cell death of human lung ...
Robert Ramer, Udo Walther, Philipp Borchert, Stefan Laufer, Michael Linnebacher, Burkhard Hinz   +5 more
doaj