Results 231 to 240 of about 4,481,323 (329)

Distinguishing aggregate formation and aggregate clearance using cell-based assays

Journal of Cell Science, 2016
E. Eenjes, J. Dragich, H. Kampinga, Ai Yamamoto   +3 more
semanticscholar   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

Molecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp   +4 more
wiley   +1 more source

Cell-based assays and comparative genomics revealed the conserved and hidden effects of Wolbachia on insect sex determination. [PDF]

PNAS Nexus
Arai H, Herran B, Sugimoto TN, Miyata M, Sasaki T, Kageyama D.   +5 more
europepmc   +1 more source

High-throughput mechanobiology: Force modulation of ensemble biochemical and cell-based assays. [PDF]

Biophys J, 2021
Dos Santos Á, Fili N, Pearson DS, Hari-Gupta Y, Toseland CP.   +4 more
europepmc   +1 more source

Novel Inhibitors of Bacterial Cytokinesis Identified by a Cell-based Antibiotic Screening Assay [PDF]

, 2005
Neil R. Stokes, Jörg Sievers, Stephanie Barker, James M. Bennett, David R. Brown, Ian Collins, Veronica M. Errington, D. Foulger, M.J. Hall, Rowena Halsey, H. E. Johnson, Valérie Rose, Helena Thomaides‐Brears, David J. Haydon, Lloyd G. Czaplewski, Jeff Errington   +15 more
openalex   +1 more source

Plants: a tool box of cell-based assays

Nature Methods, 2016
V. Marx
semanticscholar   +1 more source

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

Molecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan, Fenghua Tan, Jie Wu, Zhaoyang Zeng, Wenjia Guo, He Huang, Wei Xiong   +6 more
wiley   +1 more source

Obtainment of Flavonoid-Enriched Fractions from Maqui (<i>Aristotelia chilensis</i>) and Murta (<i>Ugni molinae</i>) Extracts via Preparative HPLC and Evaluation of Their Anti-Inflammatory Effects in Cell-Based Assays. [PDF]

Antioxidants (Basel)
Alburquenque A, Busch C, Gómez-Lillo G, Gamboa A, Perez C, Fuentes NC, Gotteland M, Abugoch L, Tapia C.   +8 more
europepmc   +1 more source

A cell-based assay for aggregation inhibitors as therapeutics of polyglutamine-repeat disease and validation in Drosophila

, 2003
Barbara L. Apostol, Alexsey Kazantsev, Simona Raffioni, Katalin Illes, Judit Pallos, László Bodai, Natalia Slepko, James E. Bear, Frank B. Gertler, Steven M. Hersch, David E. Housman, J. Lawrence Marsh, Leslie M. Thompson   +12 more
openalex   +1 more source

A Homogeneous Fluorescent Cell-Based Assay for Detection of Heterologously Expressed Nitric Oxide Synthase Activity [PDF]

, 2005
Michael W. Wood, Richard Hastings, Linda A. Sygowski   +2 more
openalex   +1 more source