Microvesicles and exosomes: new players in metabolic and cardiovascular disease [PDF]
The past decade has witnessed an exponential increase in the number of publications referring to extracellular vesicles (EVs). For many years considered to be extracellular debris, EVs are now seen as novel mediators of endocrine signalling via cell-to ...
Charlotte Lawson +21 more
core +2 more sources
High‐Concentration Antibody Formulation via Solvent‐Based Dehydration
Amorphous solid antibodies are encapsulated into hydrogel microparticles through a solvent‐based dehydration process. The solvent extracts water from antibody solution droplets, causing the antibody to concentrate, and precipitation of the antibody into amorphous solid is induced.
Talia Zheng +3 more
wiley +1 more source
Circulating Neutrophil-Derived Microparticles Associated with the Prognosis of Patients with Sepsis
Hong-Peng Chen,1,2,* Xiao-Yan Wang,1,* Xiao-Yan Pan,1 Wang-Wang Hu,1 Shu-Ting Cai,1 Kiran Joshi,3 Lie-Hua Deng,1,2 Daqing Ma3 1Department of Critical Care Medicine, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, People’s
Chen HP +7 more
doaj
Radiated tumor cell-derived microparticles effectively kill stem-like tumor cells by increasing reactive oxygen species. [PDF]
Hu Y +12 more
europepmc +1 more source
Induction of endothelial cell proliferation by recombinant and microparticle-tissue factor involves β1-integrin and extracellular signal regulated kinase activation [PDF]
Objective: Increased levels of circulating tissue factor (TF) in the form of microparticles increase the risk of thrombosis. However, any direct influence of microparticle-associated TF on vascular endothelial cell proliferation is not known.
Collier, Mary E. W., Ettelaie, Camille
core +1 more source
Residual magnetization induces pronounced mechanical anisotropy in ultra‐soft magnetorheological elastomers, shaping deformation and actuation even without external magnetic fields. This study introduces a computational‐experimental framework integrating magneto‐mechanical coupling into topology optimization for designing soft magnetic actuators with ...
Carlos Perez‐Garcia +3 more
wiley +1 more source
Coagulation factor Xa appears involved in the pathogenesis of pulmonary fibrosis. Through its interaction with protease activated receptor-1, this protease signals myofibroblast differentiation in lung fibroblasts.
Federica Novelli +10 more
doaj +1 more source
Tumor-repopulating cell-derived microparticles elicit cascade amplification of chemotherapy-induced antitumor immunity to boost anti-PD-1 therapy. [PDF]
Bie N +9 more
europepmc +1 more source
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao +6 more
wiley +1 more source
Untethered Magnetic Microswimmers for Targeted Particle Transport and Flow Manipulation
This work introduces magnetically actuated microswimmers to dynamically reconfigure fluid flow within a single microfluidic device. Multiple homogeneous microswimmers are independently controlled by an external magnetic field to perform translational and rotational motions, thereby inducing real‐time flow manipulation.
Dineshkumar Loganathan +3 more
wiley +1 more source

