Results 131 to 140 of about 36,354 (283)

Chitosan-based nanoparticles and microparticles

, 2008
Chitosan-Triphosphate Nanoparticles There is a widespread interest in the use of nano-carriers for drug delivery and chitosan is one of the most sought-after components for designing biocompatible nanoparticles. Here, using a rational experimental design,
Nasti, Alessandro
core  

Microplastics‐Induced Gut Microbiota Dysbiosis Accelerates Alzheimer's‐Like Pathology and Cognitive Decline via the Gut–Brain Axis

Advanced Science, EarlyView.
Microplastics (MPs) breach the gut‐brain axis by triggering taurine‐depleting microbiota dysbiosis that accelerates Alzheimer‐like pathology in 5XFAD mice. Taurine supplementation normalizes autophagy, microglial quiescence, and cognition, and plasma taurine inversely tracks cognitive decline in ADNI participants, revealing a readily translatable ...
Zifeng Wu, Jiarong Yang, Miaoxuan Zhang, Yi Li, Zhuling Tu, Ji Wang, Jin‐Tai Yu, Kun Guo, Rongcan Luo   +8 more
wiley   +1 more source

Drug-Loaded Tumor-Derived Microparticles Elicit CD8+ T Cell-Mediated Anti-Tumor Response in Hepatocellular Carcinoma

Yulin Chen,1 Yi Zhang,2 Jianjun Wang,3 Xiong Cai,1 Junzhang Chen,1 Xiaobo Min,1 Yunjie Xu,1 Qi Qin,1 Chidan Wan1 1Department of Hepatobiliary Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022 ...
Wan C, Qin Q, Min X, Chen J, Zhang Y, Chen Y, Wang J, Cai X, Xu Y   +8 more
core  

Condition‐Associated Pattern Extraction and Recovery From Multi‐Condition Single‐Cell RNA‐seq Data With CAPER

Advanced Science, EarlyView.
Decoupling biological signals from unwanted variation in multi‑condition single‑cell RNA sequencing data remains challenging. CAPER disentangles condition‑associated biological effects from sample heterogeneity through matrix factorization, producing interpretable latent factors and a batch‑corrected expression matrix.
Ye Li, Jin Ning, An Wang, Minxi Shi, Yuanze Chen, Guoliang Liu, Shiquan Sun   +6 more
wiley   +1 more source

Intrapleural infusion of tumor cell-derived microparticles packaging methotrexate or saline combined with pemetrexed-cisplatin chemotherapy for the treatment of malignant pleural effusion in advanced non-squamous non-small cell lung cancer: A double-blind, randomized, placebo-controlled study. [PDF]

Front Immunol, 2022
Dong X, Huang Y, Yi T, Hu C, Gao Q, Chen Y, Zhang J, Chen J, Liu L, Meng R, Zhang S, Dai X, Fei S, Jin Y, Yin P, Hu Y, Wu G.   +16 more
europepmc   +1 more source

Therapeutic potential of plasma membrane-derived microparticles

, 2009
In the past, plasma membrane-derived microparticles were considered "cellular dust." According to the literature, circulating levels of microparticles are increased in several cardiovascular diseases associated with inflammation, suggesting that ...
M.C. Martinez, R. Andriantsitohaina, T. Benameur   +2 more
core   +1 more source

Circulating levels of cell-derived microparticles are reduced by mild hypobaric hypoxia: data from a randomised controlled trial

, 2014
PURPOSE: Hypoxia is known to induce the release of microparticles in vitro. However, few publications have addressed the role of hypoxia in vivo on circulating levels of microparticles.
Ferry, Berne, Stadelmann, Katrin, Huber, Reto; https://orcid.org/, Kohler, Malcolm, Lo Cascio, Christian M, Latshang, Tsogyal D, Achermann, Peter, Ayers, Lisa, Tesler, Noemi, Stoewhas, Anne-Christin, Bloch, Konrad E, Sadler, Ross   +11 more
core   +1 more source

From Materials to Systems: Challenges and Solutions for Fast‐Charge/Discharge Na‐Ion Batteries

Advanced Energy Materials, EarlyView.
This review systematically analyzes the key characteristics limiting the fast‐charge/discharge capability of Na‐ion batteries (SIBs) from a multi‐scale perspective encompassing electrode materials, the electrode‐electrolyte interface, and the system. Furthermore, it presents practical solution strategies for the fundamental issues arising at each scale,
Bonyoung Ku, Sangbin Park, Sunha Hwang, Sunghyun Lim, Won‐Sub Yoon, Jongsoon Kim   +5 more
wiley   +1 more source

Comparative Insights and Overlooked Factors of Interphase Chemistry in Alkali Metal‐Ion Batteries

Advanced Energy Materials, EarlyView.
This review presents a comparative analysis of Li‐, Na‐, and K‐ion batteries, focusing on the critical role of electrode–electrolyte interphases. It especially highlights overlooked aspects such as SEI/CEI misconceptions, binder effects, and self‐discharge relevance, emphasizing the limitations of current understanding and offering strategies for ...
Changhee Lee, Zachary T. Gossage, Shinichi Kumakura, Shinichi Komaba   +3 more
wiley   +1 more source

Silicon‐Based Anodes for Sulfide Solid‐State Batteries: Failure Mechanisms and Multiscale Design Strategies

Advanced Energy Materials, EarlyView.
Silicon anodes in sulfide SSBs face coupled electrochemo‐mechanical failure by interface instability. This review examined recent advances and proposed mitigation strategies via material‐, electrode/interface‐, and cell‐level‐ engineering. We further evaluate scalable synthesis of sulfide SEs.
Murugesan Karuppaiah, JaeWook Seo, SeEun Park, Seung Hyeok Chu, Jung Kyoo Lee   +4 more
wiley   +1 more source