Results 261 to 270 of about 36,354 (283)
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Circulating Cell-Derived Microparticles in Crohn?s Disease

Digestive Diseases and Sciences, 2005
Procoagulant membrane microparticles can be released from activated or apoptotic cells in response to various environmental stimuli. The aim of this study was to investigate the presence of microparticles in Crohn's disease and to assess their variations after infliximab therapy.
Patrick, Chamouard   +8 more
openaire   +2 more sources

Influence of Cell-Derived Microparticles on Thromboelastography.

Blood, 2010
Abstract Abstract 3698 Background. Thromboelastography (TEG) is a method of analyzing coagulation commonly used to assess pre- and perioperative bleeding risk. We have been interested in the role of cell-derived microparticles (MP) in coagulation and in this study, examined correlations
Max E Johansen   +6 more
openaire   +1 more source

Cell‐Derived Microparticles and Exosomes in Neuroinflammatory Disorders

2007
All blood cells and the vascular endothelium shed microparticles (MP) from their plasma membranes when suitably stimulated, and assay of MP in patient blood has found increasing application to the monitoring of disease states. In addition, mounting evidence suggests that MP are not mere epiphenomena but play significant roles in the pathophysiology of ...
Lawrence L, Horstman   +6 more
openaire   +2 more sources

Pyroptotic cell-derived microparticle: An atherogenic factor in infectious diseases

Medical Hypotheses, 2021
Chronic infection is considered a risk factor for atherosclerosis. The link between infectious agents and atherosclerosis is manifested by the presence of infection-induced pyroptotic cells in atherosclerotic lesions. Pyroptosis is an inflammatory form of programmed cell death that occurs most frequently upon infection. However, inflammation is not the
Shao-Wei, Sun   +5 more
openaire   +2 more sources

Circulating Cell-Derived Microparticles as Biomarkers in Cardiovascular Disease

Biomarkers in Medicine, 2016
Cardiovascular diseases (CVDs) are a common cause of death, and a search for biomarkers for risk stratification is warranted. Elevated levels of cell-derived microparticles (MPs) are found in patients with CVD and in groups with risk factors for CVD.
Åsa, Thulin   +3 more
openaire   +2 more sources

Cell-Derived Microparticles/Exosomes in Neuroinflammation

2017
The roles of cell-derived microparticles (MP) in neuroinflammatory disorders are increasingly recognized as fundamental. Exosomes are now established as a well-defined subclass of MP. A major function is transport of many inflammatory mediators, now including gene-modulating RNA transcripts.
Lawrence L. Horstman   +2 more
openaire   +1 more source

“Kill” the messenger: Targeting of cell-derived microparticles in lupus nephritis

Autoimmunity Reviews, 2016
Immune complex (IC) deposition in the glomerular basement membrane (GBM) is a key early pathogenic event in lupus nephritis (LN). The clarification of the mechanisms behind IC deposition will enable targeted therapy in the future. Circulating cell-derived microparticles (MPs) have been proposed as major sources of extracellular autoantigens and ICs and
Nielsen, Christoffer T.   +3 more
openaire   +4 more sources

Statin and endothelial cell-derived microparticles

Thrombosis and Haemostasis, 2008
Thromb Haemost 2008; 100: 377–378 Microparticles (MP) are small membrane vesicles that are released from many different cell types by a process of exocytic budding of the plasma membrane (1). Because MP disseminate various bioactive effectors originating from the parent cells, they can alter vascular function and may induce biological responses ...
openaire   +1 more source

Cell-Derived Microparticles Promote Coagulation after Moderate Exercise

Medicine & Science in Sports & Exercise, 2011
Cell-derived procoagulant microparticles (MP) might be able to contribute to exercise-induced changes in blood hemostasis.This study aimed to examine (i) the concentration and procoagulant activity of cell-derived MP after a moderate endurance exercise and (ii) the differences in the release, clearance, and activity of MP before and after exercise ...
Maik, Sossdorf   +4 more
openaire   +2 more sources

Cell-derived microparticles after exercise in individuals with G6PD Viangchan

Clinical Hemorheology and Microcirculation, 2015
Abstract Glucose-6-phospate dehydrogenase (G6PD) deficient cells are sensitive to oxidative damage leading to the formation of microparticles (MPs). Therefore, we examined the concentration of MPs and changes in the antioxidant balance after an acute strenuous exercise (SEx) and moderate-intensity exercise (MEx).
Makamas, Chanda   +3 more
openaire   +2 more sources

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