Results 31 to 40 of about 29,386 (244)

Circulating microparticles are increased amongst people presenting with HIV and advanced immune suppression in Malawi and correlate closely with arterial stiffness: a nested case control study [version 2; peer review: 1 approved, 2 approved with reservations]

Wellcome Open Research, 2022
Background: We aim to investigate whether circulating microparticle (CMPs) subsets were raised amongst people presenting with a new diagnosis of HIV and advanced immune suppression in Malawi, and whether they associated with arterial stiffness.
Christine Kelly, Raphael Kamng'ona, Rijan Gurung, Kondwani Jambo, Mishek Chammudzi, Irene Sheha, Rob Heyderman, Jane Mallewa, Henry Mwandumba, Patrick Mallon, Saye Khoo, Nigel Klein, Alicja Rapala   +12 more
doaj   +1 more source

Glycoxidated ferritin induces the release of microparticles positive for Toll-like receptors derived from peripheral blood CD14+ cells [PDF]

Archives of Biological Sciences, 2017
Both increased serum ferritin levels and Toll-like receptor (TLR) activation show independent association with the inflammatory processes. During inflammation, cell activation and apoptosis are accompanied by the release of membrane-derived ...
López-Soto Luis Fernando, Galván-Moroyoqui José Manuel, Martínez-Soto Manuel Juan, Almada-Balderrama Martín, Rosales-Ruiz Ashley Patricia, Álvarez-Hernández Gerardo, Camacho Villa Alma Yolanda, Bolado Martínez Enrique, Soto-Guzmán Adriana, Candia-Plata Maria Del Carmen   +9 more
doaj   +1 more source

Microparticles as Potential Biomarkers of Cardiovascular Disease

Arquivos Brasileiros de Cardiologia, 2015
Primary prevention of cardiovascular disease is a choice of great relevance because of its impact on health. Some biomarkers, such as microparticles derived from different cell populations, have been considered useful in the assessment of cardiovascular ...
Carolina Nunes França, Maria Cristina de Oliveira Izar, Jônatas Bussador do Amaral, Daniela Melo Tegani, Francisco Antonio Helfenstein Fonseca   +4 more
doaj   +1 more source

Delivery of chemotherapeutic drugs in tumour cell-derived microparticles [PDF]

Nature Communications, 2012
Cellular microparticles are vesicular plasma membrane fragments with a diameter of 100-1,000 nanometres that are shed by cells in response to various physiological and artificial stimuli. Here we demonstrate that tumour cell-derived microparticles can be used as vectors to deliver chemotherapeutic drugs.
Ke, Tang, Yi, Zhang, Huafeng, Zhang, Pingwei, Xu, Jing, Liu, Jingwei, Ma, Meng, Lv, Dapeng, Li, Foad, Katirai, Guan-Xin, Shen, Guimei, Zhang, Zuo-Hua, Feng, Duyun, Ye, Bo, Huang   +13 more
openaire   +2 more sources

Cell‐derived microparticles contain caspase 3 in vitro and in vivo [PDF]

Journal of Thrombosis and Haemostasis, 2005
Microparticles (MP) from endothelial cells (endothelial microparticles; EMP) circulate in disease states, but the processes such as apoptosis or cell activation underlying their release are unclear.We investigated whether adherent (viable) or detached (apoptotic) endothelial cells are the possible source of EMP in vitro, i.e.
Abid Hussein, M. N., Nieuwland, R., Hau, C. M., Evers, L. M., Meesters, E. W., Sturk, A.   +5 more
openaire   +2 more sources

Leukocyte-derived microparticles and scanning electron microscopic structures in two fractions of fresh cerebrospinal fluid in amyotrophic lateral sclerosis: a case report

Journal of Medical Case Reports, 2012
Introduction Amyotrophic lateral sclerosis is a progressive neurodegenerative disorder characterized by degeneration of motoneuron cells in anterior spinal horns. There is a need for early and accurate diagnosis with this condition.
Zachau Anne C, Landén Mikael, Mobarrez Fariborz, Nybom Rolf, Wallén Håkan, Wetterberg Lennart   +5 more
doaj   +1 more source

Extracellular microparticles derived from hepatic progenitor cells deliver a death signal to hepatoma-initiating cells

Journal of Nanobiotechnology, 2022
The malignant transformation of normal resident hepatic stem/progenitor cells has a critical role in hepatocarcinogenesis and the recurrence of hepatocellular carcinoma (HCC). We defined such hepatic progenitor cells as hepatoma-initiating cells.
Xiaojuan Hou, Wenting Liu, Xue Yang, Changchun Shao, Lu Gao, Li Zhang, Lixin Wei   +6 more
doaj   +1 more source

Small tumour microparticle enhances drug delivery efficiency and therapeutic antitumour efficacy

Cancer Nanotechnology, 2022
Background Targeted delivery of chemotherapeutic drugs to tumour cells is a major challenge for cancer chemotherapy. Recent studies show that tumour cell-derived microparticles can be used as vectors to package chemotherapeutic drugs, and selectively ...
Zhou Jiang, Kai Li, Yongzhong Luo, Bin Chen, Fanfan Meng, Huifang Yi, Lemeng Zhang, Hua Yang, Wenwei Zhou, Tianli Cheng, Huihuang Yi, Qing Yi, Xiaoping Wen, Sheng Hu, Hongyan Liu, Jianhua Chen   +15 more
doaj   +1 more source

Immune cell-derived microparticles in polymyositis/dermatomyositis [PDF]

Annals of the Rheumatic Diseases, 2010
Microparticles are recently recognised players of intercellular communication. They are involved in signal transduction, cell activation and apoptosis. Their importance is also suggested in autoimmune diseases such as rheumatoid arthritis and systemic sclerosis. We investigated the role of microparticles in polymyositis/dermatomyositis, a group of rare
Z Baka, L Senolt, J Vencovsky, H Mann, P Sebestyén Simon, Á Kittel, E Buzás, G Nagy   +7 more
openaire   +1 more source

Mechanism of trophoblast cell‐derived microparticles mediated immunocontraceptive response

American Journal of Reproductive Immunology, 2023
AbstractProblemImmunomodulation profoundly affects the process of human implantation. Trophoblast cell‐derived microparticles (Tr‐MPs) may activate specific T cells to attack trophoblast cells, thus potentially acting as an immunocontraceptive vaccine.
Shao-Yang, Lai, Kai-Lun, Hu, Xuan, Zhou, Xiao-Xue, Li, Xiao-Jun, Yu, Jing, Shi, Jie, Zhao   +6 more
openaire   +2 more sources