Results 21 to 30 of about 29,386 (244)

Fetal hemoglobin and hydroxycarbamide moduate both plasma concentration and cellular origin of circulating microparticles in sickle cell anemia children

Haematologica, 2013
Microparticles are cell membrane-derived microvesicles released during cell apoptosis and activation processes. They have been described as bio-markers in various vascular diseases, including sickle cell anemia, and associated with an increased risk of ...
Danitza Nébor, Marc Romana, Raoul Santiago, Nathalie Vachiery, Julien Picot, Cédric Broquere, Vicky Chaar, Lydia Doumdo, Marie-Hélène Odièvre, Malika Benkerrou, Jacques Elion   +10 more
doaj   +1 more source

Circulating erythrocyte-derived microparticles are associated with coagulation activation in sickle cell disease

Haematologica, 2009
Background Sickle cell disease is characterized by a hypercoagulable state as a result of multiple factors, including chronic hemolysis and circulating cell-derived microparticles. There is still no consensus on the cellular origin of such microparticles
Eduard J. van Beers, Marianne C.L. Schaap, René J. Berckmans, Rienk Nieuwland, Augueste Sturk, Frederiek F. van Doormaal, Joost C.M. Meijers, Bart J. Biemond   +7 more
doaj   +1 more source

Release of Prometastatic Platelet-Derived Microparticles Induced by Breast Cancer Cells: A Novel Positive Feedback Mechanism for Metastasis

TH Open, 2017
Circulating platelets and platelet-derived microparticles are regulators of cancer metastasis. In this study, we show that breast cancer cells induce platelet aggregation and lead to the release of platelet-derived microparticles.
Marta Zarà, Gianni Francesco Guidetti, Daniela Boselli, Chiara Villa, Ilaria Canobbio, Claudio Seppi, Caterina Visconte, Jessica Canino, Mauro Torti   +8 more
doaj   +1 more source

Endothelial cell-derived microparticles induce plasmacytoid dendritic cell maturation: potential implications in inflammatory diseases

Haematologica, 2009
Background Increased circulating endothelial microparticles, resulting from vascular endothelium dysfunction, and plasmacytoid dendritic cell activation are both encountered in common inflammatory disorders.
Fanny Angelot, Estelle Seillès, Sabeha Biichlé, Yael Berda, Béatrice Gaugler, Joel Plumas, Laurence Chaperot, Françoise Dignat-George, Pierre Tiberghien, Philippe Saas, Francine Garnache-Ottou   +10 more
doaj   +1 more source

Proteome of endothelial cell‐derived procoagulant microparticles

PROTEOMICS, 2005
AbstractMicroparticles (MP) are small membrane vesicles that are released from cells upon activation or during apoptosis. Cellular MP in body fluids constitute a heterogeneous population, differing in cellular origin, numbers, size, antigenic composition and functional properties.
E. Tremoli, M. Brioschi, R. Wait, S. Begum, E. Gianazza, L. Mussoni, A.A. Pirillo, C. Banfi   +7 more
openaire   +5 more sources

Circulating Microparticles Are Elevated in Treated HIV‐1 Infection and Are Deleterious to Endothelial Cell Function

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Circulating microparticles have emerged as biomarkers and effectors of vascular disease. Elevated rates of cardiovascular disease are seen in HIV‐1–seropositive individuals.
Jamie G. Hijmans, Kelly A. Stockelman, Vinicius Garcia, Ma'ayan V. Levy, L. Madden Brewster, Tyler D. Bammert, Jared J. Greiner, Brian L. Stauffer, Elizabeth Connick, Christopher A. DeSouza   +9 more
doaj   +1 more source

Predicting disease progression in advanced non-small cell lung cancer with circulating neutrophil-derived and platelet-derived microparticles

BMC Cancer, 2021
Background Microparticles (MPs) are extracellular vesicles that are associated with cancer development and progression. Advanced non-small cell lung cancer (NSCLC) still shows disease progression after multiple lines of treatment.
Tingting Liu, Jiang Wang, Tao Li, Pengfei Cui, Baicun Hou, Chunxiao Zhuang, Ge Wei, Sujie Zhang, Hongxia Li, Yi Hu   +9 more
doaj   +1 more source

Cell-Derived Microparticles in the Pathogenesis of Cardiovascular Disease [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2011
Microparticles are ascribed important roles in coagulation, inflammation, and endothelial function. These processes are mandatory to safeguard the integrity of the organism, and their derangements contribute to the development of atherosclerosis and cardiovascular disease.
Tushuizen, Maarten E., Diamant, Michaela, Sturk, Augueste, Nieuwland, Rienk   +3 more
openaire   +4 more sources

Leukocyte- and endothelial-derived microparticles: a circulating source for fibrinolysis

Haematologica, 2012
Background We recently assigned a new fibrinolytic function to cell-derived microparticles in vitro. In this study we explored the relevance of this novel property of microparticles to the in vivo situation.Design and Methods Circulating microparticles ...
Romaric Lacroix, Laurent Plawinski, Stéphane Robert, Loïc Doeuvre, Florence Sabatier, Sara Martinez de Lizarrondo, Anna Mezzapesa, Francine Anfosso, Aurelie S. Leroyer, Pascale Poullin, Noémie Jourde, Makon-Sébastien Njock, Chantal M. Boulanger, Eduardo Anglés-Cano, Françoise Dignat-George   +14 more
doaj   +1 more source

Microparticles: potential new contributors to the pathogenesis of systemic sclerosis?

Advances in Rheumatology, 2023
Background Microparticles (MPs) are membrane-derived vesicles released from cells undergoing activation or apoptosis with diverse proinflammatory and prothrombotic activities, that have been implicated in the pathogenesis of systemic sclerosis (SSc).
Sandra Maximiano de Oliveira, Ighor Luiz de Azevedo Teixeira, Carolina Nunes França, Maria Cristina de Oliveira Izar, Cristiane Kayser   +4 more
doaj   +1 more source