Results 21 to 30 of about 455 (206)

Glycoxidated ferritin induces the release of microparticles positive for Toll-like receptors derived from peripheral blood CD14+ cells [PDF]

Archives of Biological Sciences, 2017
Both increased serum ferritin levels and Toll-like receptor (TLR) activation show independent association with the inflammatory processes. During inflammation, cell activation and apoptosis are accompanied by the release of membrane-derived ...
López-Soto Luis Fernando, Galván-Moroyoqui José Manuel, Martínez-Soto Manuel Juan, Almada-Balderrama Martín, Rosales-Ruiz Ashley Patricia, Álvarez-Hernández Gerardo, Camacho Villa Alma Yolanda, Bolado Martínez Enrique, Soto-Guzmán Adriana, Candia-Plata Maria Del Carmen   +9 more
doaj   +1 more source

The Role of Cell-derived Microparticles in Cardiovascular Diseases: Current Concepts

Current Pharmaceutical Design, 2022
Abstract: Cardiovascular disease remains the main cause of human morbidity and mortality in developed countries. Microparticles (MPs) are small vesicles originating from the cell membrane as a result of various stimuli and particularly of biological processes that constitute the pathophysiology of atherosclerosis, such as endothelial damage. They form
Panagiota K. Stampouloglou, Gerasimos Siasos, Evanthia Bletsa, Evangelos Oikonomou, Georgia Vogiatzi, Konstantinos Kalogeras, Efstratios Katsianos, Michael-Andrew Vavuranakis, Nektarios Souvaliotis, Manolis Vavuranakis   +9 more
openaire   +3 more sources

Microparticles: potential new contributors to the pathogenesis of systemic sclerosis?

Advances in Rheumatology, 2023
Background Microparticles (MPs) are membrane-derived vesicles released from cells undergoing activation or apoptosis with diverse proinflammatory and prothrombotic activities, that have been implicated in the pathogenesis of systemic sclerosis (SSc).
Sandra Maximiano de Oliveira, Ighor Luiz de Azevedo Teixeira, Carolina Nunes França, Maria Cristina de Oliveira Izar, Cristiane Kayser   +4 more
doaj   +1 more source

Delivery of chemotherapeutic drugs in tumour cell-derived microparticles [PDF]

Nature Communications, 2012
Cellular microparticles are vesicular plasma membrane fragments with a diameter of 100-1,000 nanometres that are shed by cells in response to various physiological and artificial stimuli. Here we demonstrate that tumour cell-derived microparticles can be used as vectors to deliver chemotherapeutic drugs.
Ke, Tang, Yi, Zhang, Huafeng, Zhang, Pingwei, Xu, Jing, Liu, Jingwei, Ma, Meng, Lv, Dapeng, Li, Foad, Katirai, Guan-Xin, Shen, Guimei, Zhang, Zuo-Hua, Feng, Duyun, Ye, Bo, Huang   +13 more
openaire   +2 more sources

Microparticles as Potential Biomarkers of Cardiovascular Disease

Arquivos Brasileiros de Cardiologia, 2015
Primary prevention of cardiovascular disease is a choice of great relevance because of its impact on health. Some biomarkers, such as microparticles derived from different cell populations, have been considered useful in the assessment of cardiovascular ...
Carolina Nunes França, Maria Cristina de Oliveira Izar, Jônatas Bussador do Amaral, Daniela Melo Tegani, Francisco Antonio Helfenstein Fonseca   +4 more
doaj   +1 more source

Predicting disease progression in advanced non-small cell lung cancer with circulating neutrophil-derived and platelet-derived microparticles

BMC Cancer, 2021
Background Microparticles (MPs) are extracellular vesicles that are associated with cancer development and progression. Advanced non-small cell lung cancer (NSCLC) still shows disease progression after multiple lines of treatment.
Tingting Liu, Jiang Wang, Tao Li, Pengfei Cui, Baicun Hou, Chunxiao Zhuang, Ge Wei, Sujie Zhang, Hongxia Li, Yi Hu   +9 more
doaj   +1 more source

Leukocyte-derived microparticles and scanning electron microscopic structures in two fractions of fresh cerebrospinal fluid in amyotrophic lateral sclerosis: a case report

Journal of Medical Case Reports, 2012
Introduction Amyotrophic lateral sclerosis is a progressive neurodegenerative disorder characterized by degeneration of motoneuron cells in anterior spinal horns. There is a need for early and accurate diagnosis with this condition.
Zachau Anne C, Landén Mikael, Mobarrez Fariborz, Nybom Rolf, Wallén Håkan, Wetterberg Lennart   +5 more
doaj   +1 more source

Biomass‐Derived Multilayer‐Structured Microparticles for Accelerated Hemostasis and Bone Repair

Advanced Science, 2020
It is very desirable to develop advanced sustainable biomedical materials with superior biosafety and bioactivity for clinical applications. Herein, biomass‐derived multilayer‐structured absorbable microparticles (MQxTy) composed of starches and plant ...
Jia‐Ying Liu, Yang Hu, Long Li, Chao Wang, Jia Wang, Yang Li, Dafu Chen, Xiaokang Ding, Chuanan Shen, Fu‐Jian Xu   +9 more
doaj   +1 more source

Cell‐derived microparticles contain caspase 3 in vitro and in vivo [PDF]

Journal of Thrombosis and Haemostasis, 2005
Microparticles (MP) from endothelial cells (endothelial microparticles; EMP) circulate in disease states, but the processes such as apoptosis or cell activation underlying their release are unclear.We investigated whether adherent (viable) or detached (apoptotic) endothelial cells are the possible source of EMP in vitro, i.e.
Abid Hussein, M. N., Nieuwland, R., Hau, C. M., Evers, L. M., Meesters, E. W., Sturk, A.   +5 more
openaire   +2 more sources

Complement Activation on Endothelial Cell-Derived Microparticles—A Key Determinant for Cardiovascular Risk in Patients with Systemic Lupus Erythematosus?

Medicina, 2020
Systemic lupus erythematosus is a classical systemic autoimmune disease that overactivates complement and can affect all organs. Early diagnosis and effective management are important in this immune-complex-mediated chronic inflammatory disease, which ...
Naomi Martin, Xiaodie Tu, Alicia J. Egan, Cordula Stover   +3 more
doaj   +1 more source