Results 11 to 20 of about 36,354 (283)

Cell-derived microparticles and the lung [PDF]

European Respiratory Review, 2016
Cell-derived microparticles are small (0.1–1 μm) vesicles shed by most eukaryotic cells upon activation or during apoptosis. Microparticles carry on their surface, and enclose within their cytoplasm, molecules derived from the parental cell, including ...
Dario Nieri, Tommaso Neri, Silvia Petrini, Barbara Vagaggini, Pierluigi Paggiaro, Alessandro Celi   +5 more
doaj   +8 more sources

Engineered Cell‐Derived Microparticles Bi2Se3/DOX@MPs for Imaging Guided Synergistic Photothermal/Low‐Dose Chemotherapy of Cancer [PDF]

Advanced Science, 2020
Cell‐derived microparticles, which are recognized as nanosized phospholipid bilayer membrane vesicles, have exhibited great potential to serve as drug delivery systems in cancer therapy.
Dongdong Wang, Yuzhu Yao, Junkai He, Xiaoyan Zhong, Basen Li, Shiyu Rao, Haiting Yu, Shuaicheng He, Xiaoyu Feng, Tuo Xu, Bin Yang, Tuying Yong, Lu Gan, Jun Hu, Xiangliang Yang   +14 more
doaj   +3 more sources

Correlations Between the Circulating Level of Cell-Derived Microparticles and Surgical Variables in Heart Valve Surgery with Cardiopulmonary Bypass [PDF]

Journal of Tehran University Heart Center, 2022
Background: Cell-derived microparticles (MPs) as membrane vesicles are procoagulant. They play a role in surgical hemostasis. In this study, the correlations between the circulating level of cell-derived MPs and surgical variables in heart valve surgery
Mehrnaz Abdolalian, Elham Khalaf-Adeli, Fatemeh Yari, Saeid Hosseini, Hooman Bakhshandeh   +4 more
doaj   +2 more sources

Cell-Derived Microparticles and Acute Coronary Syndromes: Is there a Predictive Role for Microparticles?

Current Medicinal Chemistry, 2020
Background:Despite the recent advances in the treatment of Acute Coronary Syndromes (ACS), patients with ACS are still exposed to an increased risk for adverse cardiovascular events, while their prognosis is difficult to determine. Experimental and clinical studies have shown that cell-derived Microparticles (MPs) are associated with the underlying ...
Nikolaos Papageorgiou, Dimitris Tousoulis   +1 more
exaly   +4 more sources

The Role of Cell-derived Microparticles in Cardiovascular Diseases: Current Concepts

Current Pharmaceutical Design, 2022
Abstract: Cardiovascular disease remains the main cause of human morbidity and mortality in developed countries. Microparticles (MPs) are small vesicles originating from the cell membrane as a result of various stimuli and particularly of biological processes that constitute the pathophysiology of atherosclerosis, such as endothelial damage. They form
Evangelos Oikonomou, Panagiota K Stampouloglou, Gerasimos Siasos   +2 more
exaly   +4 more sources

Chemoradiotherapy‐Integrated Tumor Cell‐Derived Microparticles Mediate Tumor Eradication in Malignant Pleural Effusion [PDF]

Journal of Extracellular Vesicles
Malignant pleural effusion (MPE) portends poor prognosis in advanced cancer. Strategies that integrate potent tumor killing with immunosuppressive microenvironment reprogramming are crucial for the treatment of MPE.
Minqi Zhou, Lingyi Kong, Weidong Zhong, Yijun Wang, Wenqian Yuan, Xixi Liu, Jiacheng Wang, Mengyao Su, Yuze Zheng, Zishan Feng, Zhiyuan Zhou, Yue Deng, Wenwen Wei, Xiao Yang, Yan Hu, Chao Wan, Yuhan Sheng, Yajie Sun, Kunyu Yang   +18 more
doaj   +2 more sources

Influence of red blood cell-derived microparticles upon vasoregulation. [PDF]

Blood Transfus, 2017
Here we review recent data and the evolving understanding of the role of red blood cell-derived microparticles (RMPs) in normal physiology and in disease progression. Microparticles (MPs) are small membrane vesicles derived from various parent cell types.
Said AS, Doctor A.
europepmc   +3 more sources

Mesenchymal stem cell-derived microparticles: a promising therapeutic strategy. [PDF]

Int J Mol Sci, 2014
Mesenchymal stem cells (MSCs) are multipotent stem cells that give rise to various cell types of the mesodermal germ layer. Because of their unique ability to home in on injured and cancerous tissues, MSCs are of great potential in regenerative medicine.
Tan X, Gong YZ, Wu P, Liao DF, Zheng XL.
europepmc   +4 more sources

Tumor cell-derived microparticles: a new form of cancer vaccine. [PDF]

Oncoimmunology, 2015
For cancer vaccines, tumor antigen availability is currently not an issue due to technical advances. However, the generation of optimal immune stimulation during vaccination is challenging. We have recently demonstrated that tumor cell-derived microparticles (MP) can function as a new form of potent cancer vaccine by efficiently activating type I ...
Zhang H, Huang B.
europepmc   +3 more sources

A novel broadband impedance method for detection of cell-derived microparticles [PDF]

Biosensors and Bioelectronics, 2010
A novel label-free method is presented to detect and quantify cell-derived microparticles (MPs) by the electrochemical potential-modulated electrochemical impedance spectroscopy (EIS). MPs are present in elevated concentrations during pathological conditions and play a major role in the establishment and pathogenesis of many diseases. Considering this,
Vadim Lvovich, Roy L Silverstein
exaly   +3 more sources