Accumulation of tissue factor in endothelial cells induces cell apoptosis, mediated through p38 and p53 activation [PDF]
, 2015 We previously reported that high levels of tissue factor (TF) can induce cellular apoptosis in endothelial. In this study, TF-mediated mechanisms of induction of apoptosis were explored.
Collier, Mary E. W. +3 more
core +1 more source
PLoS ONE, 2012 Cell-derived microparticles participate in intercellular communication similar to the classical messenger systems of small and macro-molecules that bind to specialized membrane receptors. Microparticles have been implicated in the regulation of a variety
Panpan Chen +3 more
doaj +1 more source
Communications Biology, 2021 Antonyshyn et al. establish a methodology for acquiring human adipose tissue-derived microvascular endothelial cells that can be readily applied in future vascular tissue engineering applications.
Jeremy A. Antonyshyn +6 more
doaj +1 more source
A novel biodegradable polymer scaffold for in vitro growth of corneal epithelial cells
Indian Journal of Ophthalmology, 2022 The shortage of donor corneal tissue worldwide has led to extensive research for alternate corneal equivalents utilizing tissue engineering methods. We conducted experiments using Poly D, L lactic acid polymer along with a copolymer (Eudragit) in varying
Kanika Bhardwaj, Uma Sridhar
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Modification of Pulsed Electric Field Conditions Results in Distinct Activation Profiles of Platelet-Rich Plasma. [PDF]
PLoS ONE, 2016 BACKGROUND:Activated autologous platelet-rich plasma (PRP) used in therapeutic wound healing applications is poorly characterized and standardized.
Andrew L Frelinger +9 more
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Long-term high fat feeding of rats results in increased numbers of circulating microvesicles with pro-inflammatory effects on endothelial cells [PDF]
, 2015 Obesity and type 2 diabetes lead to dramatically increased risks of atherosclerosis and CHD. Multiple mechanisms converge to promote atherosclerosis by increasing endothelial oxidative stress and up-regulating expression of pro-inflammatory molecules ...
Bastard +6 more
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Microparticle alpha‐2‐macroglobulin enhances pro‐resolving responses and promotes survival in sepsis
EMBO Molecular Medicine, 2013 Incorporation of locally produced signaling molecules into cell‐derived vesicles may serve as an endogenous mediator delivery system. We recently reported that levels alpha‐2‐macroglobulin (A2MG)‐containing microparticles are elevated in plasma from ...
Jesmond Dalli +8 more
doaj +1 more source
Biomass‐Derived Multilayer‐Structured Microparticles for Accelerated Hemostasis and Bone Repair
Advanced Science, 2020 It is very desirable to develop advanced sustainable biomedical materials with superior biosafety and bioactivity for clinical applications. Herein, biomass‐derived multilayer‐structured absorbable microparticles (MQxTy) composed of starches and plant ...
Jia‐Ying Liu +9 more
doaj +1 more source
Cell-derived microparticles in haemostasis and vascular medicine
Thrombosis and Haemostasis, 2009 SummaryConsiderable interest for cell-derived microparticles has emerged, pointing out their essential role in haemostatic response and their potential as disease markers, but also their implication in a wide range of physiological and pathological processes. They derive from different cell types including platelets – the main source of microparticles –
Burnier, Laurent +3 more
openaire +3 more sources
A new landscape of host–protozoa interactions involving the extracellular vesicles world [PDF]
, 2018 This version is free to view and download for private research and study only. Not for re-distribution, re-sale or use in derivative works. © Cambridge University Press 2018Extracellular vesicles (EVs) are released by a wide number of cells including ...
Bruno Gavinho +11 more
core +2 more sources