Results 141 to 150 of about 1,066,214 (229)

Cell-Free RNA from Plasma in Patients with Neuroblastoma: Exploring the Technical and Clinical Potential. [PDF]

Cancers (Basel), 2023
Lak NSM, Seijger A, van Zogchel LMJ, Gelineau NU, Javadi A, Zappeij-Kannegieter L, Bongiovanni L, Andriessen A, Stutterheim J, van der Schoot CE, de Bruin A, Tytgat GAM.   +11 more
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Gene Expression Profiling of EGFR, FGFR2, PIK3CA, PTEN, SMAD4, STK11, and TP53 in Cell-Free RNA From Exhaled Breath Condensate: Diagnostic, Prognostic, and Therapeutic Implications in Advanced Lung Adenocarcinoma. [PDF]

Cancer Rep (Hoboken)
Latifova S, Genis U, Karakus HS, Korba K, Ozgur S, Aldag C, Goksel T, Pelit L, Gunduz C, Vardarli AT.   +9 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Preservation of cell-free RNA in percutaneous core-needle biopsy specimens' supernatants from non-small cell lung cancer improves genomic testing performance. [PDF]

J Pathol Clin Res
Xu S, Ma YD, Bie ZX, Huang JY, Li YM, Wang Z, Li XG.   +6 more
europepmc   +1 more source

Proof of concept: Detection of cell free RNA from EDTA plasma in patients with lung cancer and non-cancer patients. [PDF]

Clin Biochem, 2023
Mullins KE, Seneviratne C, Shetty AC, Jiang F, Christenson R, Stass S.   +5 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Maternal plasma cell-free RNA as a predictor of early and late-onset preeclampsia throughout pregnancy. [PDF]

Nat Commun
Castillo-Marco N, Cordero T, Igual M, Muñoz-Blat I, Gómez-Álvarez C, Bernat-González N, Gaspar-Doménech Á, Ortiz-Domingo É, Vives A, Ortega-Sanchís S, Monfort-Ortiz R, Volkov P, Delgado JL, Hernandez-Hernandez L, Canovas E, Gil MDM, Santacruz B, Gonzalez-Gonzalez NL, Plasencia W, Perales-Marín A, Marcos-Puig B, Palacios-Marqués AM, Melchor Í, Martin-Martinez A, Benitez-Delgado T, PREMOM Consortium, Simón C, Garrido-Gómez T.   +27 more
europepmc   +1 more source

Identification of RNU44 as an Endogenous Reference Gene for Normalizing Cell-Free RNA in Tuberculosis. [PDF]

Open Forum Infect Dis, 2022
Gu W, Tu X, Lu W, Yin Y, Meng Q, Wang X, Zhang F, Fu Y.   +7 more
europepmc   +1 more source