Results 151 to 160 of about 395,472 (375)

Responses of substantia gelatinosa neurons to putative neurotransmitters in an in vitro preparation of the adult rat spinal cord [PDF]

, 1983
Extracellular recordings were performed from neurons of the substantia gelatinosa (SG) in an in vitro preparation obtained from the spinal cord of adult rats. About 40% of neurons were spontaneously active.
B. Sutor, Bennett, Cervero, Cervero, Cervero, Cervero, Coggeshall, Coggeshall, Dhanjal, Dhanjal, Dubuisson, Fry, Hentall, Hunt, Hökfelt, Kumazawa, Kumazawa, Light, Miletic, Murase, Price, Ruda, Sumal, W. Zieglgänsberger, Wall, Wall, Williams, Yoshimura, Zieglgänsberger, Zieglgänsberger   +29 more
core   +1 more source

Molecular Insights into the Specific Targeting of c-MYC G-quadruplex by Cell-Penetrating Peptides: An in silico Study

, 2023
Sen Cao, Qian Su, Yonghao Chen, Meng‐Lu Wang, Yi Xu, Lihui Wang, Yanhua Lu, Jianfeng Li, Jun Liu, Xiaojing Hong, Hongyan Wang, Junping Liu, Zhiguo Wang   +12 more
openalex   +2 more sources

Bio‐Inspired Molecular Events in Poly(Ionic Liquids)

Advanced Functional Materials, EarlyView.
Originating from dipolar and polar inter‐ and intra‐chain interactions of the building blocks, the topologies and morphologies of poly(ionic liquids) (PIL) govern their nano‐ and micro‐processibility. Modulating the interactions of cation‐anion pairs with aliphatic dipolar components enables the tunability of properties, facilitated by “bottom‐up ...
Jiahui Liu, Marek W. Urban
wiley   +1 more source

Vaccine delivery by penetratin: mechanism of antigen presentation by dendritic cells [PDF]

, 2016
Cell-penetrating peptides (CPP) or membrane-translocating peptides such as penetratin from Antennapedia homeodomain or TAT from human immunodeficiency virus are useful vectors for the delivery of protein antigens or their cytotoxic (Tc) or helper (Th) T ...
A Lenarczyk, BC Gil-Torregrosa, BP Gross, C Bechara, C Jacobs, CC Norbury, CC Norbury, Choon-Kit Tang, CM Fehres, Dodie Pouniotis, DS Pouniotis, DS Pouniotis, DT Kim, E Koren, E Vives, F Wang, G Fenteany, GA Pietersz, Geoffrey Pietersz, GG Chikh, H Umezawa, H Yang, HY Wang, I Melero, I Mellman, J Chen, J Lu, J Lu, J Pohl, JC Mai, JE Schnitzer, JP Richard, JS Blum, JS Park, K Palucka, KC Sheng, L Cohn, L Delamarre, LJ Cruz, M Kovacsovics-Bankowski, M Mansourian, MA Morse, MA West, MM Fretz, MP Schutze-Redelmeier, MP Schutze-Redelmeier, MV Dhodapkar, N Brooks, N Merzougui, N Shibagaki, NA Brooks, NA Brooks, OP Joffre, P Midoux, P Sampath, PA Orlandi, PJ Tacken, R Wallbrecher, S Kozlowski, S Sanderson, S Vassilaros, SM Farkhani, T Buhl, T Wileman, TB Potocky, V Apostolopoulos, V Apostolopoulos, V Apostolopoulos, Vasso Apostolopoulos, W Kastenmuller, WF Lo, X Wu, Y Cho, Y Jiang, Z Yang   +74 more
core   +1 more source

Biomaterials‐Based Hydrogel with Superior Bio‐Mimetic Ionic Conductivity and Tissue‐Matching Softness for Bioelectronics

Advanced Functional Materials, EarlyView.
By mimicking the ion‐accelerating effect of ion channel receptors in neuron membranes, a biomaterials‐based ionic hydrogel (BIH) is developed, which offers a high ionic conductivity of 7.04 S m−1, outperforming conventional chitosan, cellulose, agarose, starch, and gelatin based ionic hydrogels.
Baojin Chen, Renjie Yu, Jiaqi Wang, Yunxiang Feng, Yujie Zhang, Yanchao Mao, Chongxin Shan, Xudong Wang   +7 more
wiley   +1 more source

Genomic evidence for genes encoding leucine-rich repeat receptors linked to resistance against the eukaryotic extra- and intracellular Brassica napus pathogens Leptosphaeria maculans and Plasmodiophora brassicae [PDF]

, 2018
© 2018 Stotz et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Fitt, Bruce, Hossein, Borhan, Kukol, Andreas, Larkan, Nicholas, Mashanova, Alla, Parham, Haddadi, Pascoe, Harvey, Stotz, Henrik   +7 more
core   +3 more sources

Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents

Nature Communications, 2017
In vitroblood-brain barrier (BBB) models are crucial tools for screening brain-penetrating compounds. Here the authors develop a self-assembling BBB spheroid model with superior performance to the standard transwell BBB model, and use their platform to ...
Choi-Fong Cho, Justin M. Wolfe, Colin M. Fadzen, David Calligaris, Kalvis Hornburg, E. Antonio Chiocca, Nathalie Y. R. Agar, Bradley L. Pentelute, Sean E. Lawler   +8 more
doaj   +1 more source

Cell-Penetrating Peptides: Design Strategies beyond Primary Structure and Amphipathicity

Molecules, 2017
Efficient intracellular drug delivery and target specificity are often hampered by the presence of biological barriers. Thus, compounds that efficiently cross cell membranes are the key to improving the therapeutic value and on-target specificity of non ...
Daniela Kalafatovic, E. Giralt
semanticscholar   +1 more source

Selective Cell Penetrating Peptides [PDF]

, 2017
Contains fulltext : 247601.pdf (Publisher’s version ) (Open Access)
Bode, S.A., Dolstra, H., Lowik, D.W.P.M., Hest, J.C.M. van   +3 more
openaire  

Drug‐Free Thrombolysis Mediated by Physically Activated Micro/Nanoparticles

Advanced Functional Materials, EarlyView.
Overview of particle‐mediated thrombolytic effects (thermal, mechanical, and chemical) and their activating physical stimuli (light, ultrasound, and magnetic field) in drug‐free thrombolysis. ABSTRACT Thrombus‐associated disorders rank among the world's leading causes of death, with ischemic heart disease and stroke as the main contributors.
Pierre Sarfati, Yoann Lalatonne, Cédric Chauvierre   +2 more
wiley   +1 more source