Results 271 to 280 of about 61,727 (300)
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Therapeutic Potential of cell-penetrating Peptides
Therapeutic Delivery, 2013The ability of cell-penetrating peptides to cross plasma membranes has been used for various applications, including the delivery of bioactive molecules to inhibit disease-producing cellular mechanisms. Selective drug delivery into target cells improves drug distribution and decreases dosing and toxicity.
Luís, Vasconcelos +2 more
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Cell Penetrating Peptides in Drug Delivery
Pharmaceutical Research, 2004Protein transduction domains (PTDs) are small cationic peptides that can facilitate the uptake of large, biologically active molecules into mammalian cells. Recent reports have suggested that PTDs may be able to mediate the delivery of cargo to tissues throughout a living organism.
Eric L, Snyder, Steven F, Dowdy
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Peptide–glycosaminoglycan cluster formation involving cell penetrating peptides
Biopolymers, 2011AbstractGlycosaminoglycans (GAGs) affect the efficiency of cellular uptake of a wide range of cell penetrating peptides (CPPs). GAGs have been proposed to cluster with CPPs at the cell surface before uptake but little is known about the formation or stability of CPP–GAG clusters.
Anthony, Rullo, Jieshu, Qian, Mark, Nitz
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Antibacterial cell-penetrating peptides
2021The present disclosure relates to novel antibacterial cell penetrating peptides and derivatives, and methods to make and use the novel antibacterial cell-penetrating peptides and derivatives. The novel antibacterial cell-penetrating peptides of the present invention with shorter linker between a pyrrolidine ring and a guanidine group provide ...
Chmielewski, Jean, Seleem, Mohamed N.
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Therapeutic Applications of Cell-Penetrating Peptides
2010Since the discovery over 15 years ago of a protein transcription factor that possessed the ability to cross the plasma membrane, cell-penetrating peptides (CPPs) have been evaluated for the ability to transport diverse cargoes into cells, tissues, and organs.
Randolph M, Johnson +2 more
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Uptake Mechanism of Cell-Penetrating Peptides
2017Cell-penetrating peptides have been extensively used since their discovery for delivering cargoes unable to cross the cell membrane. Among other transported cargoes, they have shown very efficient delivery for oligonucleotides making cell-penetrating peptides a powerful tool for gene therapy.
Maxime, Gestin +2 more
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Cell-penetrating peptides in protein mimicry and cancer therapeutics
Advanced Drug Delivery Reviews, 2022Sarah Jones, Ülo Langel
exaly
Collagen‐like Cell‐Penetrating Peptides
Angewandte Chemie International Edition, 2013Chisato M, Yamazaki +7 more
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Cell penetrating peptides: A versatile vector for co-delivery of drug and genes in cancer
Journal of Controlled Release, 2021Muhammad Muzamil Khan +2 more
exaly