Results 141 to 150 of about 19,745,596 (363)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Small cell prostate cancer: risks for metastatic disease

Frontiers in Urology
ObjectiveTo identify clinical and demographic factors associated with the presence and distribution of metastatic disease at diagnosis in patients with small cell carcinoma of the prostate (SCCP).IntroductionSmall cell carcinoma of the prostate is a rare
Essam Al-Snayyan, Jamil Qiqieh, Cameron Peres, Sharon Tan, Susan Lyons, Avery Mendelson   +5 more
doaj   +1 more source

Differentiation of Adult Mouse Olfactory Precursor Cells into Hair Cells In Vitro [PDF]

, 2006
Kharen L. Doyle, Anita Kazda, Yvonne Hort, Sarah McKay, Sharon Oleskevich   +4 more
openalex   +1 more source

Low Cost, Adhesion Strength Based Cell Sorter [PDF]

, 2017
In many in vitro experiments, primary cells are harvested from an animal species to undergo experimental manipulation and subsequent analysis. Cell sorters are a luxury to have after cell harvesting to ensure pure populations of cells.
Burtch, Emily, Kamga-Gninzeko, Franck, Mair, Devin, Saunders, Sarah   +3 more
core   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Antiapoptotic function of Bcl-2 in mast cells is dependent on its association with heat shock protein 90β [PDF]

, 2005
Cellina Cohen‐Saidon, Irit Carmi, Avishai Keren, Ehud Razin   +3 more
openalex   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Donor cell survival and repopulation after intraarticular transplantation of tendon and ligament allografts [PDF]

, 2002
Douglas W. Jackson, Timothy M. Simon
openalex   +1 more source

Dlgh1 coordinates actin polymerization, synaptic T cell receptor and lipid raft aggregation, and effector function in T cells. [PDF]

, 2005
Lipid raft membrane compartmentalization and membrane-associated guanylate kinase (MAGUK) family molecular scaffolds function in establishing cell polarity and organizing signal transducers within epithelial cell junctions and neuronal synapses. Here, we
Miceli, M Carrie, Patel, Viresh, Round, June L, Schoenberger, Stephen P, Tomassian, Tamar, Zhang, Min   +5 more
core  

Cell Fractionation

, 2017
Protein function is generally dependent on its subcellular localisation. In Gram-negative bacteria such as Escherichia coli, a protein can be targeted to five different compartments: the cytoplasm, the inner membrane, the periplasm, the outer membrane and the extracellular medium.
Petiti, Melissa, Houot, Laetitia, Duché, Denis   +2 more
openaire   +5 more sources