Results 141 to 150 of about 26,893,016 (421)

Structural and mechanistic basis for the regulation of the chloroplast signal recognition particle by (p)ppGpp

open access: yesFEBS Letters, EarlyView.
LHCPs are transported to the thylakoid membrane via the (cp)SRP pathway. This process involves a transit complex of (cp)SRP43, (cp)SRP54 and LHCP, which interacts with (cp)FtsY and Alb3 at the membrane. GTP hydrolysis by (cp)SRP54 and (cp)FtsY triggers complex dissociation.
Victor Zegarra   +7 more
wiley   +1 more source

Construction of Cellular Substructure in Laser Powder Bed Fusion

open access: yesMetals, 2019
Cellular substructure has been widely observed in the sample fabricated by laser powder bed fusion, while its growth direction and the crystallographic orientation have seldom been studied.
Yafei Wang   +8 more
doaj   +1 more source

Design and Simulation of Cyclic Battery Tester

open access: yesPower Electronics and Drives, 2020
The paper presents an approach to the modelling of a cyclic battery tester and contains observations about lithium-ion (Li-ion) batteries, charging/discharging procedures, conditions and protections which must be observed during the testing process.
Bilansky Juraj, Lacko Milan
doaj   +1 more source

Global, regional, and national prevalence and mortality burden of sickle cell disease, 2000-2021: a systematic analysis from the Global Burden of Disease Study 2021. [PDF]

open access: yes
BACKGROUND: Previous global analyses, with known underdiagnosis and single cause per death attribution systems, provide only a small insight into the suspected high population health effect of sickle cell disease.
GBD 2021 Sickle Cell Disease Collaborators,
core   +1 more source

Parallel and convergent processing in grid cell, head-direction cell, boundary cell, and place cell networks. [PDF]

open access: yes, 2013
The brain is able to construct internal representations that correspond to external spatial coordinates. Such brain maps of the external spatial topography may support a number of cognitive functions, including navigation and memory.
Brandon, Mark P   +2 more
core   +2 more sources

Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment

open access: yesFEBS Letters, EarlyView.
This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause   +2 more
wiley   +1 more source

Isolation and Characterization of Exosomes from Cell Culture Supernatants and Biological Fluids

open access: yesCurrent Protocols in Cell Biology, 2006
Exosomes are small membrane vesicles found in cell culture supernatants and in different biological fluids. Exosomes form in a particular population of endosomes, called multivesicular bodies (MVBs), by inward budding into the lumen of the compartment ...
C. Théry   +3 more
semanticscholar   +1 more source

Expression of Innate Immune Response Genes in Liver and Three Types of Adipose Tissue in Cloned Pigs [PDF]

open access: yes, 2012
The pig has been proposed as a relevant model for human obesity-induced inflammation, and cloning may improve the applicability of this model. We tested the assumptions that cloning would reduce interindividual variation in gene expression of innate ...
Heegaard, Peter M. H.   +3 more
core   +1 more source

Immunoregulatory mechanisms of the arachidonic acid pathway in cancer

open access: yesFEBS Letters, EarlyView.
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine   +3 more
wiley   +1 more source

Replicator Dynamics of of Cancer Stem Cell; Selection in the Presence of Differentiation and Plasticity [PDF]

open access: yesarXiv, 2014
Stem cells have the potential to produce lineages of non-stem cell populations (differentiated cells) via a ubiquitous hierarchal division scheme. Differentiation of a stem cell into (partially) differentiated cells can happen either symmetrically or asymmetrically. The selection dynamics of a mutant cancer stem cell should be investigated in the light
arxiv  

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