Cell-type-specific subtyping of epigenomes improves prognostic stratification of cancer. [PDF]
Luo Q, Teschendorff AE.
europepmc +1 more source
The Occurrence of Intercellular Bridges in Groups of Cells Exhibiting Synchronous Differentiation
Don W. Fawcett+2 more
openalex +1 more source
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi+5 more
wiley +1 more source
MIST: An interpretable and flexible deep learning framework for single-T cell transcriptome and receptor analysis. [PDF]
Lai W, Li Y, Luo OJ.
europepmc +1 more source
Shape and Movement of Mesenchyme Cells as Functions of the Physical Structure of the Medium
Paul Weiß, Beatrice B. Garber
openalex +1 more source
The Immunologic Specificity of Antiserum for Trypsin-Treated Red Blood Cells and Its Reactions with Normal and Hemolytic Anemia Cells [PDF]
Matthew C. Dodd+5 more
openalex +1 more source
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric+11 more
wiley +1 more source
Non-muscle myosin heavy chain IIA regulates cell morphology, stress fibre structure, and cell migration in FLO-1 oesophageal adenocarcinoma cells. [PDF]
Duff D, Gargan S, Long A.
europepmc +1 more source
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen+17 more
wiley +1 more source
Single-cell transcriptional responses of T cells during microsporidia infection. [PDF]
Tang Y+10 more
europepmc +1 more source