Results 381 to 390 of about 26,893,016 (421)

Microglial reprogramming: a potential new frontier in enhancing immunotherapy for melanoma brain metastasis

Molecular Oncology, EarlyView.
Microglia act as tumor suppressors during brain metastasis colonization but shift to a tumor‐promoting role after melanoma brain metastases form. NF‐κB/RelA signaling emerges as a key driver of this phenotypic shift. Targeting this pathway reprograms microglia into a pro‐inflammatory state, enhancing antitumor immunity and immune checkpoint inhibitor ...
Noam Savion‐Gaiger, Dorin Bar‐Ziv, Harriet Kluger   +2 more
wiley   +1 more source

PD-1 suppression enhances HIV reactivation and T-cell immunity via MAPK/NF-κB signaling. [PDF]

Eur J Med Res
Lin X, Song B, Cao L, Zhang L, Liu S, Wang X, Chen X, Li S.   +7 more
europepmc   +1 more source

Infiltrating B-cell subtypes and associated hub genes in nasopharyngeal carcinoma identified from integrated single-cell, bulk RNA-sequencing, and immunohistochemical data. [PDF]

Hereditas
Zhong F, Chen J, Lu T, Zhang L, Liu Z, Guan C, Xiong X, Gong X, Li J.   +8 more
europepmc   +1 more source

Knowledge and attitude of dental school faculties towards stem cell therapies and their applications. [PDF]

PeerJ
Ajlan S, Ashri N.
europepmc   +1 more source

KIF14 plays a role in the regulation of the cell cycle and has implications for prognosis in clear cell renal cell carcinoma. [PDF]

BMC Urol
Wang J, Lai X, Sun Z, Feng S, Li B, Zhao H.   +5 more
europepmc   +1 more source

Pan-KRAS Inhibitors BI-2493 and BI-2865 Display Potent Antitumor Activity in Tumors with KRAS Wild-type Allele Amplification. [PDF]

Mol Cancer Ther
Tedeschi A, Schischlik F, Rocchetti F, Popow J, Ebner F, Gerlach D, Geyer A, Santoro V, Boghossian AS, Rees MG, Ronan MM, Roth JA, Lipp J, Samwer M, Gmachl M, Kraut N, Pearson M, Rudolph D.   +17 more
europepmc   +1 more source

Naringenin impairs mitochondrial function via ROS to induce apoptosis in tamoxifen resistant MCF-7 breast cancer cells. [PDF]

PLoS One
Eanes LA, Eldeeb M, Storholt D, Patel YM.   +3 more
europepmc   +1 more source

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Cell-to-Cell Heterogeneity in Trypanosomes

Annual Review of Microbiology, 2021
Recent developments in single-cell and single-molecule techniques have revealed surprising levels of heterogeneity among isogenic cells. These advances have transformed the study of cell-to-cell heterogeneity into a major area of biomedical research, revealing that it can confer essential advantages, such as priming populations of unicellular organisms
Luzak, Vanessa, Escobar, Lara, Siegel, T. Nicolai, Figueiredo, Luisa M.   +3 more
openaire   +3 more sources

The Myeloid Cell Compartment—Cell by Cell

Annual Review of Immunology, 2019
Myeloid cells are a major cellular compartment of the immune system comprising monocytes, dendritic cells, tissue macrophages, and granulocytes. Models of cellular ontogeny, activation, differentiation, and tissue-specific functions of myeloid cells have been revisited during the last years with surprising results; for example, most tissue macrophages ...
Joachim L. Schultze, Joachim L. Schultze, Kevin Bassler, Anna C. Aschenbrenner, Anna C. Aschenbrenner, Jonas Schulte-Schrepping, Stefanie Warnat-Herresthal   +6 more
openaire   +2 more sources

Cells and cell biochemistry

Nursing Standard, 2012
This article, which forms part of the life sciences series, aims to promote understanding of the basic structure and function of cells. It assists healthcare professionals to appreciate the complex anatomy and physiology underpinning the functioning of the human body. Several introductory chemical concepts and terms are outlined.
Farley, Alistair, Hendry, Charles, McLafferty, Ella   +2 more
openaire   +3 more sources