Results 1 to 10 of about 11,661,554 (317)

Cell Adhesion by Integrins. [PDF]

Physiological Reviews, 2019
Integrins are heterodimeric cell surface receptors ensuring the mechanical connection between cells and the extracellular matrix. In addition to the anchorage of cells to the extracellular matrix, these receptors have critical functions in intracellular ...
M. Bachmann, Sampo Kukkurainen, V. Hytönen, B. Wehrle-Haller   +3 more
semanticscholar   +6 more sources

A practical review on the measurement tools for cellular adhesion force [PDF]

Advances in Colloid and Interface Science 269,309-333 (2019), 2019
Cell cell and cell matrix adhesions are fundamental in all multicellular organisms. They play a key role in cellular growth, differentiation, pattern formation and migration. Cell-cell adhesion is substantial in the immune response, pathogen host interactions, and tumor development. The success of tissue engineering and stem cell implantations strongly
Gerecsei, Tamas, Horvath, Robert, Orgovan, Norbert, Peter, Beatrix, Szabo, Balint, Ungai-Salanki, Rita   +5 more
arxiv   +3 more sources

A biophysical model of cell adhesion mediated by immunoadhesin drugs and antibodies [PDF]

, 2010
A promising direction in drug development is to exploit the ability of natural killer cells to kill antibody-labeled target cells. Monoclonal antibodies and drugs designed to elicit this effect typically bind cell-surface epitopes that are overexpressed on target cells but also present on other cells.
A Ashkenazi, A Iannello, AF Wells, AJ da Silva, BJ Scallon, Byron Goldstein, C Anderson, C Fewtrell, C Wofsy, CN Ellis, DA Hammer, Daniel Coombs, DM Zhu, DM Zhu, E Jones, F Chamian, G Bell, G Majeau, GI Bell, H Koon, J Cooper, J Galon, JA Trapani, JY Shao, K Maenaka, L Arnould, LJ Harris, LM Friedman, Lucienne Chatenoud, M Dustin, MA Ghetie, Michael L. Dustin, MJ Rosenbluth, ML Dustin, ML Dustin, ML Dustin, RA Byrn, RA Clynes, Ryan N. Gutenkunst, S Chandrasekhar, S Preithner, SE Chesla, TA Waldmann, Toby Starr, Y Kaizuka, YT Bryceson   +45 more
arxiv   +10 more sources

Biomimetic emulsions reveal the effect of homeostatic pressure on cell-cell adhesion [PDF]

, 2012
Cell-cell contacts in tissues are continuously subject to mechanical forces due to homeostatic pressure and active cytoskeleton dynamics. While much is known about the molecular pathways of adhesion, the role of mechanics is less well understood. To isolate the role of pressure we present a dense packing of functionalized emulsion droplets in which ...
Brujic, Jasna, Jorjadze, Ivane, Pontani, Lea-Laetitia, Viasnoff, Virgile   +3 more
arxiv   +3 more sources

Effect of adhesion geometry and rigidity on cellular force distributions [PDF]

Phys Rev Lett 103, 048101 (2009), 2009
The behaviour and fate of tissue cells is controlled by the rigidity and geometry of their adhesive environment, possibly through forces localized to sites of adhesion. We introduce a mechanical model that predicts cellular force distributions for cells adhering to adhesive patterns with different geometries and rigidities.
Bischofs, Ilka B., Schmidt, Sebastian S., Schwarz, Ulrich S.   +2 more
arxiv   +3 more sources

Recent advance in surface modification for regulating cell adhesion and behaviors

Nanotechnology Reviews, 2020
Cell adhesion is a basic requirement for anchorage-dependent cells to survive on the matrix. It is the first step in a series of cell activities, such as cell diffusion, migration, proliferation, and differentiation.
Wenguang Yang, Wenfeng Liang, Haibo Yu
exaly   +2 more sources

High-resolution snapshots of the talin auto-inhibitory states suggest roles in cell adhesion and signaling [PDF]

Nature Communications
Talin regulates crucial cellular functions, including cell adhesion and motility, and affects human diseases. Triggered by mechanical forces, talin plays crucial roles in facilitating the formation of focal adhesions and recruiting essential focal ...
Erumbi S. Rangarajan, Julian L. Bois, Scott B. Hansen, Tina Izard   +3 more
doaj   +2 more sources

The role of cell-cell adhesion in wound healing [PDF]

, 2006
We present a stochastic model which describes fronts of cells invading a wound. In the model cells can move, proliferate, and experience cell-cell adhesion. We find several qualitatively different regimes of front motion and analyze the transitions between them.
A. Kolmogorov, A. R. Kerstein, Casey M. Schneider-Mizell, D. C. Walker, D. C. Walker, E. Moro, Evgeniy Khain, H. Sheardown, J. A. Sherratt, J. A. Sherratt, J. D. Murray, J. F. Gouyet, L. Onsager, Leonard M. Sander, M. Bramson, M. Plapp, P. K. Maini, R. A. Fisher, T. Callaghan   +18 more
arxiv   +3 more sources

Endothelial cell-cell adhesion and signaling

Experimental Cell Research, 2017
Endothelial cells line blood vessels and provide a dynamic interface between the blood and tissues. They remodel to allow leukocytes, fluid and small molecules to enter tissues during inflammation and infections. Here we compare the signaling networks that contribute to endothelial permeability and leukocyte transendothelial migration, focusing ...
C. Cerutti, A. Ridley
semanticscholar   +9 more sources

Criticality in Cell Adhesion [PDF]

Physical Review X, 2021
Version accepted for publication in Physical Review ...
Kristian Blom, Aljaž Godec
openaire   +6 more sources