Results 91 to 100 of about 11,890,652 (305)

Intercellular adhesion molecule-1

Journal of molecular medicine, 2020
The intercellular adhesion molecule (ICAM) 1 is an Ig-like cell adhesion molecule expressed by several cell types, including leukocytes and endothelial cells.
A. Stolpe, P. V. D. Saag
semanticscholar   +1 more source

Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion.

Cell Motility and the Cytoskeleton, 2005
The morphology and cytoskeletal structure of fibroblasts, endothelial cells, and neutrophils are documented for cells cultured on surfaces with stiffness ranging from 2 to 55,000 Pa that have been laminated with fibronectin or collagen as adhesive ligand.
T. Yeung, Penelope C. Georges, L. Flanagan, B. Marg, Miguelina Ortiz, M. Funaki, Nastaran Zahir, W. Ming, V. Weaver, P. Janmey   +9 more
semanticscholar   +1 more source

Thrombomodulin: A Bifunctional Modulator of Inflammation and Coagulation in Sepsis

Critical Care Research and Practice, 2012
Deregulated interplay between inflammation and coagulation plays a pivotal role in the pathogenesis of sepsis. Therapeutic approaches that simultaneously target both inflammation and coagulation hold great promise for the treatment of sepsis ...
Takayuki Okamoto, Hironobu Tanigami, Koji Suzuki, Motomu Shimaoka   +3 more
doaj   +1 more source

Integrins alpha v beta 3 and alpha v beta 5 contribute to cell attachment to vitronectin but differentially distribute on the cell surface. [PDF]

, 1991
We investigated the role of the integrins alpha v beta 3 and alpha v beta 5 in mediating vitronectin adhesion of three phenotypically distinct cell types.
Cheresh, DA, Orlando, RA, Wayner, EA
core  

Effect of adhesion geometry and rigidity on cellular force distributions

, 2009
The behaviour and fate of tissue cells is controlled by the rigidity and geometry of their adhesive environment, possibly through forces localized to sites of adhesion.
Bischofs, Ilka B., Schmidt, Sebastian S., Schwarz, Ulrich S.   +2 more
core   +1 more source

A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development

Journal of Experimental Medicine, 2006
The chemokine stromal cell–derived factor (SDF-1; also known as chemokine ligand 12 [CXCL12]) regulates many essential biological processes, including cardiac and neuronal development, stem cell motility, neovascularization, angiogenesis, apoptosis, and ...
J. Burns, B. Summers, Yu Wang, A. Melikian, R. Berahovich, Z. Miao, M. Penfold, M. Sunshine, D. Littman, C. Kuo, Kevin Wei, B. Mcmaster, K. Wright, M. Howard, T. Schall   +14 more
semanticscholar   +1 more source

Adhesion of membranes via receptor-ligand complexes: Domain formation, binding cooperativity, and active processes [PDF]

, 2009
Cell membranes interact via anchored receptor and ligand molecules. Central questions on cell adhesion concern the binding affinity of these membrane-anchored molecules, the mechanisms leading to the receptor-ligand domains observed during adhesion, and ...
Albersdörfer, Alon, Arnold, Asfaw, Auth, Baksh, Bartosz Różycki, Bayas, Bell, Bell, Bershadsky, Bruinsma, Bunnell, Burroughs, Campi, Chen, Chen, Chesla, Choudhuri, Coombs, Davis, Davis, De, Delanoe-Ayari, DeMond, Discher, Dustin, Dustin, Dustin, Dustin, Dustin, Dustin, El Alaoui Faris, Figge, Fournier, Geiger, Girard, Goetz, Gov, Gov, Gov, Grakoui, Gruhn, Heinrich Krobath, Helfrich, Hu, Huang, Ichimura, Irvine, Jeppesen, Kim, Kloboucek, Komura, Krobath, Krogsgaard, Leckband, Lee, Lin, Lin, Lipowsky, Lipowsky, Lorz, Maier, Manneville, Martin, McDonnell, Mesfin Asfaw, Monks, Moore, Moreira, Mossman, Möller, Orsello, Prost, Purbhoo, Purrucker, Qi, Ramaswamy, Raychaudhuri, Reinhard Lipowsky, Reister-Gottfried, Rich, Różycki, Różycki, Różycki, Różycki, Sabra, Sako, Schuck, Schwarz, Schütz, Seifert, Selhuber-Unkel, Shenoy, Smith, Smith, Smith, Takagi, Thomas R. Weikl, Tolentino, Tordeux, Tsourkas, Tsourkas, Varma, Weikl, Weikl, Weikl, Weikl, Weikl, Williams, Winter, Wu, Yokosuka, Yokosuka, Yokosuka, Zhang, Zhu   +116 more
core   +2 more sources

Adhesion GPCRs are widely expressed throughout the subsections of the gastrointestinal tract [PDF]

, 2012
Background: G protein-coupled receptors (GPCRs) represent one of the largest families of transmembrane receptors and the most common drug target. The Adhesion subfamily is the second largest one of GPCRs and its several members are known to mediate ...
Badiali, Luca, Cedernaes, Jonathan, Nylander, Olof, Olszewski, Pawel K., Schiöth, Helgi B., Vergoni, Anna V.   +5 more
core   +3 more sources

Contact inhibition of locomotion and mechanical cross-talk between cell-cell and cell-substrate adhesion determines the pattern of junctional tension in epithelial cell aggregates

, 2016
We generated a computational approach to analyze the biomechanics of epithelial cell aggregates, either island or stripes or entire monolayers, that combines both vertex and contact-inhibition-of-locomotion models to include both cell-cell and cell ...
Caldwell, Benjamin J., Coburn, Luke, Gomez, Guillermo A., Lobaskin, Vladimir, Lopez, Hender, Moussa, Elliott, Neufeld, Zoltan, Noppe, Adrian, Priya, Rashmi, Roberts, Anthony P., Yap, Alpha S., Yap, Chloe   +11 more
core   +1 more source

Contractile forces at tricellular contacts modulate epithelial organization and monolayer integrity

Nature Communications, 2017
EpCAM is an unconventional epithelia-specific cell–cell adhesion molecule, that is mutated in the majority of cases of Congenital Tufting Enteropathy. Here the authors show that loss of EpCAM causes a concentration of contractile activity at tricellular ...
Julie Salomon, Cécile Gaston, Jérémy Magescas, Boris Duvauchelle, Danielle Canioni, Lucie Sengmanivong, Adeline Mayeux, Grégoire Michaux, Florence Campeotto, Julie Lemale, Jérôme Viala, Françoise Poirier, Nicolas Minc, Jacques Schmitz, Nicole Brousse, Benoit Ladoux, Olivier Goulet, Delphine Delacour   +17 more
doaj   +1 more source