Results 91 to 100 of about 12,139,065 (402)

Cultured microvascular endothelial cells derived from the bovine corpus luteum possess NCAM-140 [PDF]

open access: yes, 1992
Previously, five phenotypically different, stable types of microvascular endothelial cells (MVE) were isolated from the bovine corpus and cultured successfully. We found that three out of these five types of MVE express the neural cell adhesion molecule (
Caney   +11 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Human Microphysiological Models of Intestinal Tissue and Gut Microbiome

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
The gastrointestinal (GI) tract is a complex system responsible for nutrient absorption, digestion, secretion, and elimination of waste products that also hosts immune surveillance, the intestinal microbiome, and interfaces with the nervous system ...
Steven N. Steinway   +5 more
doaj   +1 more source

Intercellular adhesion molecule-1

open access: yesJournal of molecular medicine, 2020
The intercellular adhesion molecule (ICAM) 1 is an Ig-like cell adhesion molecule expressed by several cell types, including leukocytes and endothelial cells.
A. Stolpe, P. V. D. Saag
semanticscholar   +1 more source

Cancer-associated epithelial cell adhesion molecule (EpCAM; CD326) enables epidermal Langerhans cell motility and migration in vivo

open access: yes, 2012
After activation, Langerhans cells (LC), a distinct subpopulation of epidermis-resident dendritic cells, migrate from skin to lymph nodes where they regulate the magnitude and quality of immune responses initiated by epicutaneously applied antigens ...
Feng, X.   +7 more
core   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Loss of X-linked Protocadherin-19 differentially affects the behavior of heterozygous female and hemizygous male mice

open access: yesScientific Reports, 2017
Mutations in the X-linked gene Protocadherin-19 (Pcdh19) cause female-limited epilepsy and mental retardation in humans. Although Pcdh19 is known to be a homophilic cell-cell adhesion molecule, how its mutations bring about female-specific disorders ...
Shuichi Hayashi   +6 more
doaj   +1 more source

The Rac3 GTPase in Neuronal Development, Neurodevelopmental Disorders, and Cancer

open access: yesCells, 2019
Rho family small guanosine triphosphatases (GTPases) are important regulators of the cytoskeleton, and are critical in many aspects of cellular and developmental biology, as well as in pathological processes such as intellectual disability and cancer. Of
Ivan de Curtis
doaj   +1 more source

A role for GLUT3 in glioblastoma cell invasion that is not recapitulated by GLUT1

open access: yesCell Adhesion & Migration, 2021
The multifaceted roles of metabolism in invasion have been investigated across many cancers. The brain tumor glioblastoma (GBM) is a highly invasive and metabolically plastic tumor with an inevitable recurrence. The neuronal glucose transporter 3 (GLUT3)
Catherine J Libby   +17 more
doaj   +1 more source

A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development

open access: yesJournal of Experimental Medicine, 2006
The chemokine stromal cell–derived factor (SDF-1; also known as chemokine ligand 12 [CXCL12]) regulates many essential biological processes, including cardiac and neuronal development, stem cell motility, neovascularization, angiogenesis, apoptosis, and ...
J. Burns   +14 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy