Results 21 to 30 of about 1,406,940 (355)
Sharpin suppresses β1-integrin activation by complexing with the β1 tail and kindlin-1
Cell Communication and Signaling, 2019 Background Previously sharpin has been identified as an endogenous inhibitor of β1-integrin activation by directly binding to a conserved region in the cytoplasmic tails (CTs) of the integrin β1-associated α subunits. Methods Here we employed biochemical
Juan Gao +12 more
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Frontiers in Cell and Developmental Biology, 2020 Integrins are transmembrane proteins that mediate cellular adhesion and migration to neighboring cells or the extracellular matrix, which is essential for cells to undertake diverse physiological and pathological pathways.
Eun Jeong Park +8 more
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Annual Review of Cell and Developmental Biology, 2010 Rolling adhesion on vascular surfaces is the first step in recruiting circulating leukocytes, hematopoietic progenitors, or platelets to specific organs or to sites of infection or injury. Rolling requires the rapid yet balanced formation and dissociation of adhesive bonds in the challenging environment of blood flow.
Rodger P, McEver, Cheng, Zhu
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Biomedicines, 2021 Thrombomodulin is a molecule with anti-coagulant and anti-inflammatory properties. Recently, thrombomodulin was reported to be able to bind extracellular matrix proteins, such as fibronectin and collagen; however, whether thrombomodulin regulates the ...
Eiji Kawamoto +16 more
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Cardiosphere-derived cells demonstrate metabolic flexibility that Is influenced by adhesion status [PDF]
, 2017 Adult stem cells demonstrate metabolic flexibility that is regulated by cell adhesion status. The authors demonstrate that adherent cells primarily utilize glycolysis, whereas suspended cells rely on oxidative phosphorylation for their ATP needs.
Abraham, M. Roselle +13 more
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Circulating LPS from gut microbiota leverages stenosis-induced deep vein thrombosis in mice
Thrombosis Journal, 2023 Objective and design An accumulating body of evidence has shown that gut microbiota is involved in regulating inflammation; however, it remains undetermined if and how gut microbiota plays an important role in modulating deep venous thrombosis (DVT ...
Cheng Liu +9 more
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International Journal of Cell Biology, 2012 During cancer progression, cells lose their original tissue contacts, move through the extracellular matrix (ECM), enter into the lymphatic and/or blood system, extravasate, and ultimately form new tumors. Therefore, tumor cells inevitably experience alterations in cell-cell and cell-ECM adhesion and the transformation activities of tumor cells are ...
Eok-Soo Oh +3 more
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On the adhesion of vesicles by cell adhesion molecules
Biophysical Journal, 1985 This paper gives a detailed analysis of experiments on the kinetics of aggregation of lipid vesicles containing neural cell adhesion molecules (N-CAM). An explanation for the dependence of the "initial aggregation rate," kagg, on the square of the vesicle concentration is given, accounting both for Brownian motion of the vesicles and shear effects.
Bell, G.I., Torney, D.C.
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Measuring cell adhesion forces with the atomic force microscope at the molecular level [PDF]
, 2002 In the past 25 years many techniques have been developed to characterize cell adhesion and to quantify adhesion forces. Atomic force microscopy (AFM) has been used to measure forces in the pico-newton range, an experimental technique known as force ...
Benoit, M., Gaub, H. E.
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A Method to Culture GABAergic Interneurons Derived from the Medial Ganglionic Eminence
Frontiers in Cellular Neuroscience, 2018 Understanding the mechanisms guiding interneuron development is a central aspect of the current research on cortical/hippocampal interneurons, which is highly relevant to brain function and pathology.
Sira A. Franchi +8 more
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