Results 81 to 90 of about 11,890,652 (305)
The cell adhesion molecule Fasciclin2 regulates brush border length and organization in Drosophila renal tubules [PDF]
Multicellular organisms rely on cell adhesion molecules to coordinate cell–cell interactions, and to provide navigational cues during tissue formation.
Davies, Shireen-Anne+7 more
core +2 more sources
Loss of contact inhibition of locomotion in the absence of JAM-A promotes entotic cell engulfment
Summary: Entosis is a cell competition process during which tumor cells engulf other tumor cells. It is initiated by metabolic stress or by loss of matrix adhesion, and it provides the winning cell with resources derived from the internalized cell. Using
Mariel F. Schwietzer+8 more
doaj
Human Microphysiological Models of Intestinal Tissue and Gut Microbiome
The gastrointestinal (GI) tract is a complex system responsible for nutrient absorption, digestion, secretion, and elimination of waste products that also hosts immune surveillance, the intestinal microbiome, and interfaces with the nervous system ...
Steven N. Steinway+5 more
doaj +1 more source
A cytoskeletal protein keratin 19 (K19) is highly expressed in breast cancer but its effects on breast cancer cell mechanics are unclear. In MCF7 cells where K19 expression is ablated, we found that K19 is required to maintain rounded epithelial-like ...
Sarah Alsharif+12 more
doaj +1 more source
YAP regulates cell mechanics by controlling focal adhesion assembly
Hippo effectors YAP/TAZ act as on–off mechanosensing switches by sensing modifications in extracellular matrix (ECM) composition and mechanics. The regulation of their activity has been described by a hierarchical model in which elements of Hippo pathway
G. Nardone+15 more
semanticscholar +1 more source
A role for GLUT3 in glioblastoma cell invasion that is not recapitulated by GLUT1
The multifaceted roles of metabolism in invasion have been investigated across many cancers. The brain tumor glioblastoma (GBM) is a highly invasive and metabolically plastic tumor with an inevitable recurrence. The neuronal glucose transporter 3 (GLUT3)
Catherine J Libby+17 more
doaj +1 more source
Cell adhesive peptides functionalized on CoCr alloy stimulate endothelialization and prevent thrombogenesis and restenosis [PDF]
Immobilization of bioactive peptide sequences on CoCr surfaces is an effective route to improve endothelialization, which is of great interest for cardiovascular stents. In this work, we explored the effect of physical and covalent immoblization of RGDS,
Castellanos, Maria Isabel+8 more
core +3 more sources
Mutations in the X-linked gene Protocadherin-19 (Pcdh19) cause female-limited epilepsy and mental retardation in humans. Although Pcdh19 is known to be a homophilic cell-cell adhesion molecule, how its mutations bring about female-specific disorders ...
Shuichi Hayashi+6 more
doaj +1 more source
The Rac3 GTPase in Neuronal Development, Neurodevelopmental Disorders, and Cancer
Rho family small guanosine triphosphatases (GTPases) are important regulators of the cytoskeleton, and are critical in many aspects of cellular and developmental biology, as well as in pathological processes such as intellectual disability and cancer. Of
Ivan de Curtis
doaj +1 more source
Role of laminin and cognate receptors in cholangiocarcinoma cell migration
Extensive desmoplasia in cholangiocarcinoma (CCA) is associated with tumor aggressiveness, indicating a need for further understanding of CCA cell–matrix interaction.
Kittiya Islam+4 more
doaj +1 more source