Results 261 to 270 of about 10,810 (302)
cGMP Signaling in the Cardiovascular System—The Role of Compartmentation and Its Live Cell Imaging
International Journal of Molecular Sciences, 2018 The ubiquitous second messenger 3′,5′-cyclic guanosine monophosphate (cGMP) regulates multiple physiologic processes in the cardiovascular system. Its intracellular effects are mediated by stringently controlled subcellular microdomains.
Nadja I Börk +2 more
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Rapid fractionation of mitochondria from mouse liver and heart reveals in vivo metabolite compartmentation [PDF]
FEBS Letters, 2023 : The compartmentation and distribution of metabolites between mitochondria and the rest of the cell is a key parameter of cell signalling and pathology.
Ana S H Costa +2 more
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Compartmentalization of the Cell Membrane
Journal of Molecular Biology, 2016Many cell-membrane-associated processes require transient spatiotemporal separation of components on scales ranging from a couple of molecules to micrometers in size. Understanding these processes mechanistically involves understanding how lipids and proteins self-organize and interact with the cell cortex. Here, we review recent advances in dissecting
Honigmann, A., Pralle, A.
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Compartmentation of cholesterol within the cell
Current Opinion in Lipidology, 1994Mammalian cells tightly regulate their cholesterol content and the intracellular disposition of cholesterol. Most cellular free cholesterol resides in the plasma membrane, where it exists in lateral domains. Mechanisms governing cellular cholesterol levels and compartmentation are still largely unknown.
L, Liscum, J R, Faust
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Compartmentalization of Ca2+ in sickle cells
Cell Calcium, 1985Control (AA) and sickle cell anemia (SS) erythrocytes were loaded with Ca-chelator (Quin2 or Benz2) to increase the cellular exchangeable Ca2+ pool and to measure the Ca2+ exchange fluxes and the cytosolic ionized Ca2+ ([Ca]i) (Lew et al., 1982, Nature, 298, 478).
M D, Rhoda +3 more
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Compartmentalization of polyamines in mammalian cells
Biochemical and Biophysical Research Communications, 1982A rapid method for the separation of cytoplasm and nuclei has been adapted for polyamine analysis of the different compartments of BSC-1 cells. The whole cells contain putrescine, spermidine and spermine at concentrations of 7.3, 6.5, and 12.4 nmol/106 cells respectively.
M, Mach, P, Ebert, R, Popp, A, Ogilvie
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Lung Compartmentalization of Inflammatory Cells in Sepsis
Inflammation, 2000Lung injury commonly occurs in the setting of systemic inflammatory response syndrome occurring during bacterial sepsis. There has been little work quantifying different leukocytes within the different compartments of the lung and their association with overt lung injury in sepsis.
K, Yin +4 more
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Compartmentalization of regulatory proteins in the cell nucleus
The Journal of Steroid Biochemistry and Molecular Biology, 2001The cell nucleus is increasingly recognized as a spatially organized structure. In this review, the nature and controversies associated with nuclear compartmentalization are discussed. The relationship between nuclear structure and organization of proteins involved in the regulation of RNA polymerase II-transcribed genes is then discussed.
M J, Hendzel +5 more
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A stochastic compartmental model of bone cells
International Journal of Bio-Medical Computing, 1987Cellular dynamics play an important role in bone remodelling. The mesenchymal cells, osteoclasts, osteoblasts and osteocytes are the four types of bone cells, which mediate bone remodelling involving bone formation and resorption throughout the human life-span.
N P, Reddy, A M, Joshi
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Compartmentalization of human natural killer cells
Molecular Immunology, 2005Human natural killer (NK) cells are bone marrow-derived cells that are found in the bloodstream, but can extravasate into various tissue sites upon inflammation. NK cells that migrate toward inflamed sites must be activated prior to their extravasation. However, the factors responsible for NK cell compartmentalization are not clearly defined.
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