LAFITE Reveals the Complexity of Transcript Isoforms in Subcellular Fractions [PDF]
Advanced Science, 2023 Characterization of the subcellular distribution of RNA is essential for understanding the molecular basis of biological processes. Here, the subcellular nanopore direct RNA‐sequencing (DRS) of four lung cancer cell lines (A549, H1975, H358, and HCC4006)
Jizhou Zhang +7 more
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Isolation of Chromatin-bound Proteins from Subcellular Fractions for Biochemical Analysis [PDF]
Bio-Protocol, 2018 Shuttling of proteins between different cellular compartments controls their proteostasis and can contribute in some cases to regulate their activity.
Sébastien Gillotin
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Veterinary fluoroquinolones as emerging contaminants in marine environments: In vitro study of biochemical responses in subcellular fractions of the Mediterranean mussel (Mytilus galloprovincialis) [PDF]
HeliyonFluoroquinolone antibiotics (FQs) are emerging pollutants frequently detected in aquatic environments. However, their impact on marine invertebrates remains underexplored.
J. Giannessi +6 more
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Mechanical Fractionation of Cultured Neuronal Cells into Cell Body and Neurite Fractions
Bio-Protocol, 2021 Many cells contain spatially defined subcellular regions that perform specialized tasks enabled by localized proteins. The subcellular distribution of these localized proteins is often facilitated by the subcellular localization of the RNA molecules that
Ankita Arora +3 more
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Application of RNA subcellular fraction estimation method to explore RNA localization regulation
G3: Genes, Genomes, Genetics, 2021 RNA localization is involved in multiple biological processes. Recent advances in subcellular fractionation-based sequencing approaches uncovered localization pattern on a global scale. Most of existing methods adopt relative localization ratios (such as
Xiaomin Dai +8 more
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Scientific Reports, 2022 Subcellular organelles have long been an interest in biochemical research and drug development as the isolation of those organelles can help to probe protein functions and elucidate drug disposition within the cell.
Xiazi Qiu +2 more
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Subcellular partitioning of protein kinase activity revealed by functional kinome profiling
Scientific Reports, 2022 Protein kinases and their substrates form signaling networks partitioned across subcellular compartments to facilitate critical biological processes. While the subcellular roles of many individual kinases have been elucidated, a comprehensive assessment ...
Lauren Wegman-Points +6 more
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Biomedicines, 2021 Alzheimer’s disease (AD) is characterized by the accumulation of extracellular plaques composed by amyloid-β (Aβ) and intracellular neurofibrillary tangles of hyperphosphorylated tau.
Tânia Fernandes +8 more
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Distinct Intracellular Compartments Involved in Invariant Chain Degradation and Antigenic Peptide Loading of Major Histocompatibility Complex (MHC) Class II Molecules [PDF]
, 1997 Major histocompatibility complex (MHC) class II molecules are transported to intracellular MHC class II compartments via a transient association with the invariant chain (Ii).
Ferrari, G. +3 more
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Uterine Endoplasmic Reticulum Stress and Its Unfolded Protein Response May Regulate Caspase 3 Activation in the Pregnant Mouse Uterus [PDF]
, 2013 We have previously proposed that uterine caspase-3 may modulate uterine contractility in a gestationally regulated fashion. The objective of this study was to determine the mechanism by which uterine caspase-3 is activated and consequently controlled in ...
Condon, Jennifer C. +5 more
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