Results 41 to 50 of about 95,299 (308)

Identification of novel rhoptry proteins in Neospora caninum by LC/MS-MS analysis of subcellular fractions

, 2011
Apicomplexan parasites possess an apical complex that is composed of two secretory organelles recognized as micronemes and rhoptries. Rhoptry contents are secreted into the parasitophorous vacuole during the host cell invasion process.
G. Álvarez-García, Alvarez-Garcia, G., A. Hemphill, Hemphill, A., Marugan-Hernandez, V., L.M. Ortega-Mora, Tomley, F., J. Regidor-Cerrillo, F. Tomley, Regidor-Cerrillo, J., V. Marugán-Hernández, Ortega-Mora, L.M.   +11 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Maladaptive response to pressure overload is associated with redistribution of microtubules into distinct subcellular fractions.

, 2013
LV lysates from WT and MACF1 KO hearts exposed to control or TAC conditions were separated into cytosolic fractions (Free), Microtubule fractions (MT), trition soluble membrane fractions (Membrane), and triton insoluble cytoskeletal fraction(CSK) Equal ...
Xiaoyu Liu (206872), Xin Xu (11989), Xinli Hu (463448), John T. Fassett (463446), Yingjie Chen (463450), Robert J. Bache (463449), Huan Wang (109286), Dongmin Kwak (463447)   +7 more
core   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Prion subcellular fractionation reveals infectivity spectrum, with a high titre-low PrP^res level disparity

Molecular Neurodegeneration, 2012
Background Prion disease transmission and pathogenesis are linked to misfolded, typically protease resistant (PrPres) conformers of the normal cellular prion protein (PrPC), with the former posited to be the principal constituent of the infectious 'prion'
Lewis Victoria, Haigh Cathryn L, Masters Colin L, Hill Andrew F, Lawson Victoria A, Collins Steven J   +5 more
doaj   +1 more source

Detoxification of diazinon by subcellular fractions of diazinon-resistant and susceptible houseflies

, 1969
RESP ...
Lewis, T.
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Protocol to determine the subcellular localization of protein interactions in murine keratinocytes

STAR Protocols, 2023
Summary: Protein activities and interactions are determined by their subcellular localization. Elucidating the network of protein-protein interactions at a spatial resolution is essential for understanding the complexity of protein functions, their ...
Lisa Müller
doaj   +1 more source

Collection of FOCUS™ SubCell Protocols For the Enrichment of Subcellular Fractions v1

, 2016
This is a collection of G-Biosciences FOCUS™ SubCell protocols for the enrichment of subcellular fractions. Please refer to the appropriate protocol depending on your application.
G-Biosciences not provided
core   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source