Phosphorylation of nuclear Tau is modulated by distinct cellular pathways [PDF]
, 2018 Post-translational protein modification controls the function of Tau as a scaffold protein linking a variety of molecular partners. This is most studied in the context of microtubules, where Tau regulates their stability as well as the distribution of ...
Boersema, Paul +8 more
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Subcellular Fractionation of Cultured Human Cell Lines
Bio-Protocol, 2013 Subcellular localization is crucial for the proper functioning of a protein. Deregulation of subcellular localization may lead to pathological consequences and result in diseases like cancer.
Zhuoyou Yu, Zhiguang Huang, Maria Lung
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Cholesterol metabolism in myelin and other subcellular fractions of rat brain
Journal of Lipid Research, 1972 For many years the bulk of myelin in adult brain was believed to be metabolically stable, although some metabolic activity of a small myelin fraction, especially in the gray matter of the brain, was recognized.
Martha Spohn, A.N. Davison
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Retrograde trafficking of Argonaute 2 acts as a rate-limiting step for de novo miRNP formation on endoplasmic reticulum–attached polysomes in mammalian cells [PDF]
, 2020 microRNAs are short regulatory RNAs in metazoan cells. Regulation of miRNA activity and abundance is evident in human cells where availability of target messages can influence miRNA biogenesis by augmenting the Dicer1-dependent processing of precursors ...
Barman, Bahnisikha +4 more
core
Molecular Control of the Amount, Subcellular Location and Activity State of Translation Elongation Factor 2 (eEF-2) in Neurons Experiencing Stress [PDF]
, 2013 Eukaryotic elongation factor 2 (eEF-2) is an important regulator of the protein translation machinery wherein it controls the movement of the ribosome along the mRNA.
Argüelles-Castilla, Sandro +5 more
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Export of functional Streptomyces coelicolor alditol oxidase to the periplasm or cell surface of Escherichia coli and its application in whole-cell biocatalysis [PDF]
, 2009 Streptomyces coelicolor A3(2) alditol oxidase (AldO) is a soluble monomeric flavoprotein in which the flavin cofactor is covalently linked to the polypeptide chain.
AJ Driessen +44 more
core +8 more sources
Subcellular localization of hexadecanedioic acid activation in human liver
Journal of Lipid Research, 1974 The activation of hexadecanedioic acid has been studied in subcellular fractions of human liver. The activation capacity in a total homogenate of human liver was found to be 0.5 μmole/min/g wet wt of tissue, about 10% of that for palmitic acid ...
Jon Elling Pettersen, Magne Aas
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Инфекция и иммунитет, 2022 Immuno-serological diagnostic tools particularly identifying pathogen antigens are the most important methods of pseudotuberculosis studies. The main immunodominant and species-specific antigens located in the surface structures of the bacterial cell are
Anna V. Kryukova +9 more
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Differential Localization of G Protein βγ Subunits [PDF]
, 2014 G protein βγ subunits play essential roles in regulating cellular signaling cascades, yet little is known about their distribution in tissues or their subcellular localization.
Baucum, Anthony J. +6 more
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HMG CoA reductase of intestinal mucosa and liver of the rat
Journal of Lipid Research, 1972 Methods were developed for the determination of HMG CoA (3-hydroxy-3-methylglutaryl CoA) reductase activity in subcellular fractions of intestinal mucosa and liver of Wistar strain rats.
S. Shefer +3 more
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