Results 11 to 20 of about 593 (218)
Cholesterol Depletion Alters Cardiomyocyte Subcellular Signaling and Increases Contractility. [PDF]
PLoS ONE, 2016 Membrane cholesterol levels play an important factor in regulating cell function. Sarcolemmal cholesterol is concentrated in lipid rafts and caveolae, which are flask-shaped invaginations of the plasma membrane.
Mohammed Z Haque +4 more
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Cells, 2022 Metastasis is the primary cause of colorectal cancer (CRC) death. The liver and lung, besides adjacent lymph nodes, are the most common sites of metastasis.
Guillermo Solís-Fernández +13 more
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Subcellular Fractionation of Cultured Human Cell Lines
Bio-Protocol, 2013 Subcellular localization is crucial for the proper functioning of a protein. Deregulation of subcellular localization may lead to pathological consequences and result in diseases like cancer.
Zhuoyou Yu, Zhiguang Huang, Maria Lung
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LAFITE Reveals the Complexity of Transcript Isoforms in Subcellular Fractions
Advanced Science, 2023 Characterization of the subcellular distribution of RNA is essential for understanding the molecular basis of biological processes. Here, the subcellular nanopore direct RNA‐sequencing (DRS) of four lung cancer cell lines (A549, H1975, H358, and HCC4006)
Jizhou Zhang +7 more
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Cholesterol metabolism in myelin and other subcellular fractions of rat brain
Journal of Lipid Research, 1972 For many years the bulk of myelin in adult brain was believed to be metabolically stable, although some metabolic activity of a small myelin fraction, especially in the gray matter of the brain, was recognized.
Martha Spohn, A.N. Davison
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Инфекция и иммунитет, 2022 Immuno-serological diagnostic tools particularly identifying pathogen antigens are the most important methods of pseudotuberculosis studies. The main immunodominant and species-specific antigens located in the surface structures of the bacterial cell are
Anna V. Kryukova +9 more
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Subcellular localization of hexadecanedioic acid activation in human liver
Journal of Lipid Research, 1974 The activation of hexadecanedioic acid has been studied in subcellular fractions of human liver. The activation capacity in a total homogenate of human liver was found to be 0.5 μmole/min/g wet wt of tissue, about 10% of that for palmitic acid ...
Jon Elling Pettersen, Magne Aas
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Subcellular Fractionation and Proteomics of Nuclear Envelopes [PDF]
, 2008 Because of its many connections to other cell systems, the nuclear envelope (NE)is essentially impossible to purify to homogeneity. To circumvent these problems, we developed a subtractive proteomics approach in which the fraction of interest and a fraction known to contaminate the fraction of interest are separately analyzed, and proteins identified ...
Florens, Laurence +2 more
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Preparation of Crude Subcellular Fractions by Differential Centrifugation
The Scientific World Journal, 2002 The employment of differential centrifugation to prepare crude fractions of subcellular particles from homogenates is often a necessary first step to a subsequent purification of one or more particles on a density gradient.
John Graham
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Lipid composition of subcellular particles of human blood platelets
Journal of Lipid Research, 1969 Human platelets can be fractionated into three main subcellular components: granules, membranes, and a soluble fraction. In this study we determined the phospholipid and neutral lipid content of the granules and membranes.
Aaron J. Marcus +2 more
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