Results 161 to 170 of about 13,207,162 (409)

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

Assessment of subclinical mastitis diagnostic accuracy by differential cell count in individual cow milk

open access: yesItalian Journal of Animal Science, 2019
The progressive decrease of mean SCC in dairy herds worldwide is affecting SCC accuracy as a subclinical mastitis marker. This evidence supports studies aiming to apply differential cell count (DSCC) as a tool to identify mastitis.
Alfonso Zecconi   +4 more
doaj   +1 more source

The epidemiology of mastitis in Australian dairy cattle : a dissertation submitted in partial fulfilment of the requirements for the degree of Masters of Veterinary Studies (Epidemiology) [PDF]

open access: yes, 2000
This study represents an aggregation of knowledge on mastitis within the Australian dairy industry. Aspects of the epidemiology and economics of mastitis have been collated and areas of missing knowledge identified.
Shephard, Richard William
core  

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Absolute lymphocyte count: A cost-effective method of monitoring HIV-infected individuals

open access: yesIndian Journal of Pathology and Microbiology, 2011
Aim: Depletion of CD4 cell count is a hallmark of disease progression in AIDS. CD4 cell count is essential for physicians to decide about the timing of initiation of antiretroviral therapy (ART) and for prophylaxis of opportunistic infections.
A Kakar   +6 more
doaj   +1 more source

People, Penguins and Petri Dishes: Adapting Object Counting Models To New Visual Domains And Object Types Without Forgetting [PDF]

open access: yesarXiv, 2017
In this paper we propose a technique to adapt a convolutional neural network (CNN) based object counter to additional visual domains and object types while still preserving the original counting function. Domain-specific normalisation and scaling operators are trained to allow the model to adjust to the statistical distributions of the various visual ...
arxiv  

Characteristics, Determinants, and Clinical Relevance of CD4 T Cell Recovery to <500 Cells/µL in HIV Type 1—Infected Individuals Receiving Potent Antiretroviral Therapy [PDF]

open access: yes, 2017
Background. The CD4 T cell count recovery in human immunodeficiency virus type 1 (HIV-1)—infected individuals receiving potent antiretroviral therapy (ART) shows high variability. We studied the determinants and the clinical relevance of incomplete CD4 T
Battegay, Manuel   +10 more
core  

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

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