Results 111 to 120 of about 10,542,794 (310)
Functional validation of cancer stem cell markers in primary human colorectal cancer and established cell lines [PDF]
, 2014 In an increasing number of cancers, CSCs have been defined on the basis of the self-renewal and tumor initiation capacity by functional assays. It has been also suggested that CSC populations might be responsible for chemo- and radio-therapy resistance ...
Muraro, Manuele Giuseppe
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Cell culture engineering: part 2 [Frontiers of biomedical engineering ]
, 2014 Educação Superior::Ciências Biológicas::Biologia GeralEducação Superior::Ciências Biológicas::BioquímicaEducação Superior::Engenharias::Engenharia BiomédicaPresents the lecture by Professor Saltzman.
Saltzman, W. Mark
core
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Advances in Characterization of Industrial Bioreactors for Cell Culture Process
, 2023 Aerated stirred tank reactors are widely used in the biopharmaceutical industry for cell culture applications due to their flexibility and broad range of uses.
Haase, Ingrid +5 more
core +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Cell culture engineering: part 1 [Frontiers of biomedical engineering]
, 2016 Educação Superior::Ciências Biológicas::BioquímicaEducação Superior::Engenharias::Engenharia BiomédicaEducação Superior::Ciências Biológicas::Biologia GeralEducação Superior::Ciências Biológicas::GenéticaPresents a lecture by Professor Saltzman.
Saltzman, W. Mark
core +1 more source
Assessing morpho-chemical and genetic diversity in acid limes germplasm using microsatellite markers
Notulae Botanicae Horti Agrobotanici Cluj-NapocaAcid limes are highly nutraceutical and have great market demand. In Pakistan, two lime varieties are cultivated including ‘Mexican lime’ and ‘Eustis limequat’. Hence, other potential varieties were characterized for morphogenetic variability.
Arooge FATIMA +3 more
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source