Results 141 to 150 of about 17,149,914 (409)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Only complete rejoining of DNA strand breaks after UVC allows K562 cell proliferation and DMSO induction of erythropoiesis [PDF]

open access: yes, 2008
DNA strand breaks are early intermediates of the repair of UVC-induced DNA damage, however, since they severely impair cellular activities, their presence should be limited in time.
AVALLONE, BICE, FORESTI, MAGDA
core   +1 more source

Interactions Between Fibroblast Cells and Laser Beam Welded AISI 2205 Duplex Stainless Steel

open access: yesMedžiagotyra, 2018
Because of their high mechanical strength, excellent corrosion resistance and good weldability, duplex stainless steels are mostly used in industries such as oil, chemistry, petrochemistry, food and occasionally used in medical industry. These properties
Ceyhun KÖSE   +5 more
doaj   +1 more source

Cell Culture [PDF]

open access: yesMechanical Engineering, 2001
This article focuses on Tribon Bearing Co. plant in Brook Park, OH, a manufacturer of discrete carbon composite parts and shapes that had been plagued by problems that threatened its existence. The old Tribon plant was a traditional manufacturing setup, in which operations were highly compartmentalized.
openaire   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Ultraviolet microscopy aids in cytological and biomedical research [PDF]

open access: yes, 1967
Ultraviolet microscopy is used by cytologists and biochemists to study the morphological and physiological changes in the living cell under varied culture conditions.
Schlenk, F., Svihla, B.
core   +1 more source

Gene expression and immunohistochemistry analysis of ADAMTS-1 and its substrates in odontogenic keratocyst

open access: yesDiagnostic Pathology
Background Considering the significant participation of the microenvironment in the local aggressiveness of odontogenic keratocysts, this study aims to evaluate the expression of ADAMTS-1 and its substrates, versican, aggrecan and brevican in this ...
Osvaldo Rodrigues de Souza Neto   +7 more
doaj   +1 more source

Green technology meets ecotoxicology

open access: yesCroatian Journal of Food Science and Technology, 2016
By applying concept and principles of green chemistry into different technological processes, green technologies are developed. The environmental and economic benefits of “green” approach is achieved through several directions, such as the use of ...
Kristina Radošević   +4 more
doaj   +1 more source

3D Cell Culture

open access: yesMethods in Molecular Biology, 2017
3D cell culture is an invaluable tool in developmental, cell, and cancer biology. By mimicking crucial features of in vivo environment, including cell–cell and cell–extracellular matrix interactions, 3D cell culture enables proper structural architecture
Z. Koledova
semanticscholar   +1 more source

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