Results 221 to 230 of about 17,196,917 (410)

Study of pharmaceutical industrial problems [PDF]

The growth of a human colon carcinoma cell line (SK-CO-1) and its production of carcinoembryonic antigen (CEA) in monolayer culture and on single layers of glass beads in unit gravity were evaluated.
Pincus, J. H.
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Successful cell culture isolation and experimental pathogenicity evaluation of porcine bocavirus G3. [PDF]

Virulence
Hu Y, Min J, Xu H, Li L, Shi Y, Wu H, Zheng J, Fu N, Xu M, Sun J, Zhou Y, Chen J, Yang T, Sun W.   +13 more
europepmc   +1 more source

FP446IN VITRO EFFECTS OF SNF472 ON OSTEOBLAST CELL CULTURE [PDF]

, 2019
Geert J. Behets, Miguel D. Ferrer, M. Mar Perez, Carolina Salcedo, Joan Perelló, Patrick C. D’Haese   +5 more
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Establishment of an Osteoblastic Osteosarcoma Cell Line and Effects of Cell Culture Conditions on Secretion of Matrix Metalloproteinases from the Cultured Osteosarcoma Cells.

, 2000
Kazuhito Minamitani
openalex   +2 more sources

Algal culture studies for CELSS [PDF]

Microalgae are well-suited as a component of a Closed Environmental Life Support System (CELSS), since they can couple the closely related functions of food production and atmospheric regeneration.
Arnett, K., Behrens, P., Cox, J., Gladue, R., Lieberman, D., Radmer, R.   +5 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Cell Culture in a Hyperbaric Chamber: A Research Model to Study the Effects of Hyperbarism (Hyperbaric Pressure) on Bone Cell Culture. [PDF]

Cells
Mariano A, Consalvi V, Marchetti E, Rodio A, Scotto d'Abusco A, Fattorini L.   +5 more
europepmc   +1 more source

Interrogating Plant Cell Culture Library for Novel Antimicrobial Agents

, 2020
John Solitro, Yong Zhang, Vanessa Bartolo, Alexander Popchuk, Sergey N. Savinov, Lin-Jun Ma, Jennifer Normanly, Tristram G. Seidler, Elizabeth Vierling   +8 more
openalex   +1 more source